Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jerry E. Mellem"'
Autor:
Dayton J. Goodell, Frank G. Whitby, Jerry E. Mellem, Ning Lei, Penelope J. Brockie, Aleksander J. Maricq, Debra M. Eckert, Christopher P. Hill, David M. Madsen, Andres V. Maricq
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113694- (2024)
Summary: N-methyl-D-aspartate (NMDA)-type ionotropic glutamate receptors have essential roles in neurotransmission and synaptic plasticity. Previously, we identified an evolutionarily conserved protein, NRAP-1, that is required for NMDA receptor (NMD
Externí odkaz:
https://doaj.org/article/0e71df12b48a4b31bdc42865b9f71de6
Autor:
Frédéric J. Hoerndli, Penelope J. Brockie, Rui Wang, Jerry E. Mellem, Angy Kallarackal, Rachel L. Doser, Dayton M. Pierce, David M. Madsen, Andres V. Maricq
Publikováno v:
Cell Reports. 38:110577
Synaptic plasticity depends on rapid experience-dependent changes in the number of neurotransmitter receptors. Previously, we demonstrated that motor-mediated transport of AMPA receptors (AMPARs) to and from synapses is a critical determinant of syna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe5a6865fe5d671195a7a37d50dbaf8e
https://doi.org/10.1016/j.celrep.2022.110577
https://doi.org/10.1016/j.celrep.2022.110577
Autor:
Rui Wang, Frédéric J. Hoerndli, David M. Madsen, Colin Thacker, Penelope J. Brockie, Andres V. Maricq, Jerry E. Mellem, Angy J. Kallarackal
Publikováno v:
Neuron. 86:457-474
Summary Excitatory glutamatergic synaptic transmission is critically dependent on maintaining an optimal number of postsynaptic AMPA receptors (AMPARs) at each synapse of a given neuron. Here, we show that presynaptic activity, postsynaptic potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10c13fab1f8cbcf7bd7d669c820cb6ad
https://doi.org/10.1016/j.neuron.2015.03.011
https://doi.org/10.1016/j.neuron.2015.03.011
Autor:
Frédéric J. Hoerndli, Dane Maxfield, Andres V. Maricq, Jerry E. Mellem, David M. Madsen, Penelope J. Brockie, Rui Wang, Erica Jensen
Publikováno v:
Neuron. 80:1421-1437
Summary A primary determinant of the strength of neurotransmission is the number of AMPA-type glutamate receptors (AMPARs) at synapses. However, we still lack a mechanistic understanding of how the number of synaptic AMPARs is regulated. Here, we sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a6a019b4f140fa3ba4d9e69ec1f9202
https://doi.org/10.1016/j.neuron.2013.10.050
https://doi.org/10.1016/j.neuron.2013.10.050
Autor:
Frédéric J. Hoerndli, David M. Madsen, Penelope J. Brockie, Dane Maxfield, Colin Thacker, Andres V. Maricq, Tokiwa Yamasaki, Patrick Dunn, Erica Jensen, Jerry E. Mellem, Rui Wang, Michael K. Jensen, Susumu Tomita
Publikováno v:
Neuron. 80:129-142
SummaryThe strength of synaptic communication at central synapses depends on the number of ionotropic glutamate receptors, particularly the class gated by the agonist AMPA (AMPARs). Cornichon proteins, evolutionarily conserved endoplasmic reticulum c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbc2cd231a67a42d25d1b213375b6db7
https://doi.org/10.1016/j.neuron.2013.07.028
https://doi.org/10.1016/j.neuron.2013.07.028
Autor:
Linda Hauth, Craig S. Walker, Michael K. Jensen, Penelope J. Brockie, Rui Wang, Jerry E. Mellem, Frédéric J. Hoerndli, Andres V. Maricq, David M. Madsen
Publikováno v:
Neuron. 75(5):838-850
Summary The neurotransmitter glutamate mediates excitatory synaptic transmission by gating ionotropic glutamate receptors (iGluRs). AMPA receptors (AMPARs), a subtype of iGluR, are strongly implicated in synaptic plasticity, learning, and memory. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21475364d053b54f410717b1406e234f
Autor:
Andres V. Maricq, Penelope J. Brockie, Craig S. Walker, Rui Wang, David M. Madsen, Jerry E. Mellem, Michael M. Francis
Publikováno v:
Neuron. 59:997-1008
SummaryNeurotransmission in the brain is critically dependent on excitatory synaptic signaling mediated by AMPA-class ionotropic glutamate receptors (AMPARs). AMPARs are known to be associated with Transmembrane AMPA receptor Regulatory Proteins (TAR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b702ced78bd0fa8b5e214d8105b002d6
https://doi.org/10.1016/j.neuron.2008.07.023
https://doi.org/10.1016/j.neuron.2008.07.023
Autor:
Penelope J. Brockie, David M. Madsen, Craig S. Walker, Andres V. Maricq, Jerry E. Mellem, Michael M. Francis, Yi Zheng
Publikováno v:
Proceedings of the National Academy of Sciences. 103:1100-1105
Most rapid excitatory synaptic signaling in the brain is mediated by postsynaptic ionotropic glutamate receptors (iGluRs) that are gated open by the neurotransmitter glutamate. In Caenorhabditis elegans , sol-1 encodes a CUB-domain transmembrane prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a41355a2bc262a1b361f4fb1a1d6af5
https://doi.org/10.1073/pnas.0504612103
https://doi.org/10.1073/pnas.0504612103
Publikováno v:
Proceedings of the National Academy of Sciences. 101:3190-3195
Chronic changes in neural activity trigger a variety of compensatory homeostatic mechanisms by which neurons maintain a normal level of synaptic input. Here we show that chronic activity blockade triggers a compensatory change in the abundance of GLR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b02588f1bd86711965e8434d493db3ac
https://doi.org/10.1073/pnas.0306156101
https://doi.org/10.1073/pnas.0306156101
Publikováno v:
Neuron. 31(4):617-630
The N-methyl-D-aspartate (NMDA) subtype of glutamate receptor is important for synaptic plasticity and nervous system development and function. We have used genetic and electrophysiological methods to demonstrate that NMR-1, a Caenorhabditis elegans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4de442b133ead3e6595604929b1e2d43