Výsledky vyhledávání - "Jerry DiSalvo"

Discovery of structurally diverse natural product antagonists of chemokine receptor CXCR3

Autor: Weerachai Nanakorn, Hiranthi Jayasuriya, Michael J. Balick, Marc Slattery, Cori M. Morenberg, Jon D. Polishook, John G. Ondeyka, Ziqiang Guan, Anne W. Dombrowski, Jerry DiSalvo, Marina Mojena, Gregory E. Koch, Dennis W. Stevenson, Robert P. Borris, Kithsiri Herath, Julie A. DeMartino, Gerald F. Bills, Sheo B. Singh

Publikováno v: Molecular Diversity. 9:123-129

The chemokines (CXCL9, CXCL10 and CXCL11) and associated CXCR3 receptor are expressed during the inflammatory process from multiple sclerosis, atherosclerosis or organ transplantation resulting in the recruitment of lymphocytes leading to tissue dama

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d870205eb6edb51ba1765b5b95f3e0e
https://doi.org/10.1007/s11030-005-1296-8

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CCR5, CXCR4, and CD4 Are Clustered and Closely Apposed on Microvilli of Human Macrophages and T Cells

Autor: S Scott, Sandra L. Gould, Jayne Chin, Lorraine Malkowitz, Janet Lineberger, Salvatore J. Siciliano, Julie A. DeMartino, Hollis R. Williams, Lyndon J. Mitnaul, Michael D. Miller, Jerry DiSalvo, Mary Jo Staruch, Douglas W. Kawka, Irwin I. Singer, H J Zweerink, Martin S. Springer, Bruce L. Daugherty

Publikováno v: Journal of Virology. 75:3779-3790

The chemokine receptors CCR5 and CXCR4 act synergistically with CD4 in an ordered multistep mechanism to allow the binding and entry of human immunodeficiency virus type 1 (HIV-1). The efficiency of such a coordinated mechanism depends on the spatial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fd8dc807c3480fd27282da4d0af59a7
https://doi.org/10.1128/jvi.75.8.3779-3790.2001

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In vitro studies on L-771,688 (SNAP 6383), a new potent and selective α1A-adrenoceptor antagonist

Autor: Mark G. Bock, Charles Gluchowski, Sriram Tyagarajan, Quanrong Shen, Tsing-Bau Chen, Mohammad R. Marzabadi, Carlos Forray, Dhanapalan Nagarathnam, Wai C. Wong, Stacey O'Malley, Barbara Francis, Dhar T G Murali, Douglas J. Pettibone, Jerry DiSalvo, Roger M. Freidinger, Miao Shou Wu, Raymond S.L. Chang, Bharat Lagu

Publikováno v: European Journal of Pharmacology. 409:301-312

L-771,688 (SNAP 6383, methyl(4S)-4-(3, 4-difluorophenyl)-6-[(methyloxy)methyl]-2-oxo-3-[(?3-[4-(2-pyridin yl)-1-piperidinyl]propyl?amino)carbonyl]-1,2,3, 4-tetrahydro-5-pyrimidine carboxylate) had high affinity (Ki less than or = 1 nM) for [3H]prazos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9435f2baa4a2313af28f3841b322f801
https://doi.org/10.1016/s0014-2999(00)00854-2

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Characterization of specific binding of L-762,459, a selective α1A-adrenoceptor radioligand to rat and human tissues

Autor: Dhanapalan Nagarathnam, Stacey O'Malley, Tsing B Chen, Charles Gluchowski, H. Donald Burns, Raymond E. Gibson, John M. Wetzel, Jerry DiSalvo, Raymond S.L. Chang, Barbara Francis, Mohammad R. Marzabadi, Marvin L. Bayne

Publikováno v: European Journal of Pharmacology. 348:287-295

L-762,459 ((±)1-(3-{[5-carbamoyl-2-{2-[(4-hydroxy-3-iodobenzimidoyl)-amino]-ethoxy-methyl}-6-methyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3-carbonyl]-amino}-propyl)-4-phenyl-1-piperidine-4-carboxylic acid methyl ester), an analog of a series of dihy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eaf5e7de7f2ac6ae529120605aaa7655
https://doi.org/10.1016/s0014-2999(98)00149-6

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Conversion of cysteine to serine residues alters the activity, stability, and heparin dependence of acidic fibroblast growth factor

Autor: Sagrario Ortega, Denis D. Soderman, Jerry DiSalvo, Guillermo Giménez-Gallego, David L. Linemeyer, Marie-Therese Schaeffer, Kenneth A. Thomas

Publikováno v: Journal of Biological Chemistry. 266:5842-5846

Acidic fibroblast growth factor (aFGF) is a broad spectrum mitogen that is stabilized by complexation with heparin and heparan proteoglycans. The monomeric human protein contains 3 reduced cysteine residues of unknown function, the first 2 of which a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f83ce25a85a54907ab87693f80f2df64
https://doi.org/10.1016/s0021-9258(19)67674-x

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X-ray crystal structure of human acidic fibroblast growth factor

Autor: Michael Blaber, Jerry DiSalvo, Kenneth A. Thomas

Publikováno v: Biochemistry. 35(7)

Fibroblast growth factors (FGFs) are mitogenic and chemotactic agents for a wide variety of cell types and play a primary role in the regulation of angiogenesis. Angiogenesis is involved in a variety of critical physiological events including organog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::243fa6740978e2e0bfd11db637709d9f
https://pubmed.ncbi.nlm.nih.gov/8652550

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Purification and characterization of a naturally occurring vascular endothelial growth factor.placenta growth factor heterodimer

Autor: Perry W. Kwok, Denis D. Soderman, Greg Conn, Marvin L. Bayne, Thomas M. Palisi, Kenneth A. Thomas, Jerry DiSalvo, Prashant Trivedi, Kathleen A. Sullivan

Publikováno v: The Journal of biological chemistry. 270(13)

Vascular endothelial growth factor (VEGF) is a potent and selective mitogen for endothelial cells that is angiogenic in vivo and induced by hypoxia. A homologous protein, placenta growth factor (PlGF), is also reported to be mitogenic for endothelial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c199d262687e984729edcff9e5bcf68b
https://pubmed.ncbi.nlm.nih.gov/7706320

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Acidic fibroblast growth factor accelerates dermal wound healing

Autor: Theodore N. Mellin, Robert J. Mennie, Doreen E. Cashen, John J. Ronan, Joanna Capparella, Mary Lou James, Jerry Disalvo, John Frank, David Linemeyer, Guillermo Gimenez-Gallego, Kenneth A. Thomas

Publikováno v: Growth factors (Chur, Switzerland). 7(1)

Acidic fibroblast growth factor (aFGF) is a potent mitogen in vitro for many cells of ectodermal and mesodermal embryonic origin including skin-derived epidermal keratinocytes, dermal fibroblasts and vascular endothelial cells. Based on the mitogenic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a5961b1ab625eaee3705e92614459fb
https://pubmed.ncbi.nlm.nih.gov/1380253

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