Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Jerry C P Yin"'
Autor:
Peter Serrano, Eugenia L Friedman, Jana Kenney, Stephen M Taubenfeld, Joshua M Zimmerman, John Hanna, Cristina Alberini, Ann E Kelley, Stephen Maren, Jerry W Rudy, Jerry C P Yin, Todd C Sacktor, André A Fenton
Publikováno v:
PLoS Biology, Vol 6, Iss 12, Pp 2698-2706 (2008)
How long-term memories are stored is a fundamental question in neuroscience. The first molecular mechanism for long-term memory storage in the brain was recently identified as the persistent action of protein kinase Mzeta (PKMzeta), an autonomously a
Externí odkaz:
https://doaj.org/article/1bfbe7a0f11e48f285b78ebd5198a9c3
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e45130 (2012)
cAMP response element-binding protein (CREB) and nuclear factor kappa-B (NF-κB) are two ubiquitous transcription factors involved in a wide number of cellular processes, including the circadian system. Many previous studies on these factors use cell
Externí odkaz:
https://doaj.org/article/f0248369d0fa4407ac0131d5d2701ca7
Fatty-acid binding proteins modulate sleep and enhance long-term memory consolidation in Drosophila.
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e15890 (2011)
Sleep is thought to be important for memory consolidation, since sleep deprivation has been shown to interfere with memory processing. However, the effects of augmenting sleep on memory formation are not well known, and testing the role of sleep in m
Externí odkaz:
https://doaj.org/article/112166b9cd2c44b88ed210e8d2de0986
Publikováno v:
PLoS Biology, Vol 5, Iss 10, p e265 (2007)
Tolerance to drugs that affect neural activity is mediated, in part, by adaptive mechanisms that attempt to restore normal neural excitability. Changes in the expression of ion channel genes are thought to play an important role in these neural adapt
Externí odkaz:
https://doaj.org/article/20683790ed0246c192be776995c1edd6
Autor:
Daniel J Kelley, Richard J Davidson, Jamie L Elliott, Garet P Lahvis, Jerry C P Yin, Anita Bhattacharyya
Publikováno v:
PLoS ONE, Vol 2, Iss 9, p e931 (2007)
Fragile X syndrome (FX), the most common heritable cause of mental retardation and autism, is a developmental disorder characterized by physical, cognitive, and behavioral deficits. FX results from a trinucleotide expansion mutation in the fmr1 gene
Externí odkaz:
https://doaj.org/article/7bb58cd129b64a66ad3a9cdddfc8848b
Publikováno v:
Frontiers in Systems Neuroscience. 17
The role of the circadian system in memory formation is an important question in neurobiology. Despite this hypothesis being intuitively appealing, the existing data is confusing. Recent work in Drosophila has helped to clarify certain aspects of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ed805a4b66c17ee87e34d1d43c6058a
Circadian regulation is a conserved phenomenon across the animal kingdom, and its disruption can have severe behavioral and physiological consequences. Core circadian clock proteins are likewise well conserved from Drosophila to humans. While the mol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67a654509f2c521c1ef1c06fdca3e9e2
https://europepmc.org/articles/PMC6064670/
https://europepmc.org/articles/PMC6064670/
Publikováno v:
Human Molecular Genetics. 25:837-852
Huntington's disease (HD) is a progressive neurological disorder whose non-motor symptoms include sleep disturbances. Whether sleep and activity abnormalities are primary molecular disruptions of mutant Huntingtin (mutHtt) expression or result from n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a07e9921a99b1a36d05cfa67c1e94b90
https://doi.org/10.1093/hmg/ddv482
https://doi.org/10.1093/hmg/ddv482
Publikováno v:
Neurobiology of Learning and Memory. 118:80-88
CREB (cAMP response element-binding protein) is an evolutionarily conserved transcription factor, playing key roles in synaptic plasticity, intrinsic excitability and long-term memory (LTM) formation. The Drosophila homologue of mammalian CREB, dCREB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57f52782aa37d35fbefaedc1cd97ed31
https://doi.org/10.1016/j.nlm.2014.11.010
https://doi.org/10.1016/j.nlm.2014.11.010
Autor:
Jason R. Gerstner, Samantha M. Riedy, Allan I. Pack, Takeo Yoshikawa, Marcos G. Frank, Raymond J. Galante, Isaac J. Perron, Hans P. A. Van Dongen, Yuji Owada, Jerry C. P. Yin, Hiroshi Kadotani, Kaitlin Dickinson
Publikováno v:
Science Advances
The astrocyte brain-type fatty acid binding protein FABP7 regulates sleep consolidation across phylogeny.
Sleep is found widely in the animal kingdom. Despite this, few conserved molecular pathways that govern sleep across phyla have been descri
Sleep is found widely in the animal kingdom. Despite this, few conserved molecular pathways that govern sleep across phyla have been descri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62fe8f477728011dd9f5144f4b767049
http://europepmc.org/articles/PMC5381954
http://europepmc.org/articles/PMC5381954