Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jerry C H Tam"'
Autor:
Carl Graham, Thomas Lechmere, Aisha Rehman, Jeffrey Seow, Ashwini Kurshan, Isabella Huettner, Thomas J A Maguire, Jerry C H Tam, Daniel Cox, Christopher Ward, Mariusz Racz, Anele Waters, Christine Mant, Michael H Malim, Julie Fox, Katie J Doores
Publikováno v:
PLoS Pathogens, Vol 18, Iss 10, p e1010882 (2022)
COVID-19 vaccines are playing a vital role in controlling the COVID-19 pandemic. As SARS-CoV-2 variants encoding mutations in the surface glycoprotein, Spike, continue to emerge, there is increased need to identify immunogens and vaccination regimens
Externí odkaz:
https://doaj.org/article/38e17544a9d446ba9acc595cb5f39fb8
Publikováno v:
PLoS Pathogens, Vol 11, Iss 10, p e1005253 (2015)
Encapsidation is a strategy almost universally employed by viruses to protect their genomes from degradation and from innate immune sensors. We show that TRIM21, which targets antibody-opsonized virions for proteasomal destruction, circumvents this p
Externí odkaz:
https://doaj.org/article/b86ace7174324237b3feeb9bbf05ff47
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8902 (2010)
Streptococcus pneumoniae is a common cause of infection in both HIV positive patients and those with complement deficiencies. We hypothesised that HIV positive individuals might exhibit reduced opsonisation of pneumococcus with complement due to redu
Externí odkaz:
https://doaj.org/article/69bbe49562b4456a9199f2b7e249cb09
Autor:
Douglas L Fink, Helen Callaby, Akish Luintel, William Beynon, Helena Bond, Eleanor Y Lim, Effrossyni Gkrania-Klotsas, Jospeh Heskin, Margherita Bracchi, Balram Rathish, Iain Milligan, Geraldine O'Hara, Stephanie Rimmer, Joanna R Peters, Lara Payne, Nisha Mody, Bethany Hodgson, Penny Lewthwaite, Rebecca Lester, Stephen D Woolley, Ann Sturdy, Ashley Whittington, Leann Johnson, Nathan Jacobs, John Quartey, Brendan AI Payne, Stewart Crowe, Ivo AM Elliott, Thomas Harrison, Joby Cole, Katie Beard, Tomas-Paul Cusack, Imogen Jones, Rishi Banerjee, Tommy Rampling, Jake Dunning, Iain D Milligan, Alison J Rodger, Sanjay R Bhagani, Lucy E Lamb, Rachel C Moores, Simon F K Lee, Colin S Brown, Susan Hopkins, Stephen Mepham, Simon Warren, Aoife Molloy, Ian Cropley, Alex Kew, Natasha Karunaharan, Antonia Scobie, Jennifer Hart, Dianne Irish, Tanzina Haque, Hamid Jalal, Robin Smith, Damien Mack, Tristan Barber, Fiona Burns, Robert Miller, Eleanor Hamlyn, Pedro Simoes, Breda Athan, Jennifer Abrahamsen, Jessica Joyce, Caroline Taylor, Sally Reddecliffe, Chloe Miller, Brooke Reeve, Hugh Kingston, Tim Crocker-Buque, Nicolas Massie, Ankush Dhariwal, Angelina Jayakumar, Robert Hammond, Alexandra Bramley, Tanmay Kanitkar, Laura Maynard-Smith, Eliza Gil, Cavan O'Connor, Derek Cocker, Wendy Spicer, Marisa Lanzman, Meera Thacker, Zoe O Anorson, Dharmesh Patel, Alan Williams, Catherine F Houlihan, Dominic Wakerley, Claire N Gordon, Daniel J Bailey, Jenna Furneaux, Abbie M Bown, Elizabeth J Truelove, Marian J Killip, David Jackson, Tracy L B Beetar-King, Ulrike M V Arnold, Rhea M Strachan, Jones Matthew, Hannah J Matthew, Jane C Osborne, Richard Vipond, Barry Gibney, Jodie Owen, Will Beynon, Michael Hunter, Louise McCorry, Carol Emerson, Say Quah, Suzanne Todd, Emma McCarty, Eoin Walker, Susan Feeney, Tanya Curran, Kathy Li, JD Mullan, Kate Jackson, Peter Nelson, Kevin Lewis, Mark McNicol, Marcus Pratt, Anna Smith, Erin Vos, Fahad Alsalemee, Daniel O Leary, John Canny, Katherine McGinnity, Carly Culbert, Conor McDowell, Cathy McQuillan, Eunjin Jeong, Lynsey Glass, Jessica Dyche, Paula McClean, Rebecca Stewart, Harold Ursolino, Melissa Perry, Hannah McCormick, Joseph Heskin, Nicklas Brown, Thomas Juniper, Borja Mora-Peris, Alessia Dalla-Pria, Nicola Mackie, Lucy Garvey, Alan Winston, Graham Cooke, Mark Nelson, Emer Kilbride, Ala Elbishi, William Kerrigan, Joshua Silva, Jesal Gohil, Sasha Payagala, Yasmin Walters, Joanna Smith, Jonathan Goodfellow, Kitty Lyons, Hsiu Tung, Kinjal Patel, Merle Henderson, Michael Butler, Edu Peres, Taiana Silva Carvalho, Antoine Joly, Molly Dickinson, Luke S P Moore, Nabeela Mughal, Stephen Hughes, Shrada Chitlangia, Priyanka Viramgana, Ruth Byrne, Paul Randell, Luigi Strangis, Nicola Poveda, Deborah Bovey, Poppy Richardson, Vivian Heaslip, Christopher Higgs, Marta Boffito, Nicolo Girometti, Gary Whitlock, Victoria Tittle, Rachel Jones, Michael Rayment, Christopher Scott, David Asboe, Marcus Pond, David Muir, Movin Abeywickrema, Sarah-Lou Bailey, Sara E Boyd, Dayana Da Silva Fontoura, Anna Daunt, Claire Y Mason, Jamie Murphy, Vasanth V Naidu, Aatish Patel, Caitlin Pley, Ethan Redmore, Katherine Sharrocks, Luke B Snell, Rohan Sundramoorthi, Jerry C H Tam, Aisling Brown, Sam Douthwaite, Anna Goodman, Gaia Nebbia, William Newsholme, Nicholas Price, Emily Shaw, Alex Salam, Claire van Nispen tot Pannerden, Helen Winslow, Julia Bilinska, Sarah Keegan, Harry Coleman, Jessica Doctor, Nasreen Moini, Daniella Chilton, Golaleh Haidari, Rebecca Simons, Rajababu Kulasegaram, Nick Larbalestier, Achyuta Nori, Jack R Potter, Cecilia Tuudah, Paul Wade, Alexandra Travers, Sarah Dunford, Joshua Greenwood, Georgina Oledimmah, Lesley Gyampo, Pedro SA Pinto, AbdulKadir Muse, Zoe Parker, Charlotte Alexander, Alexander Khan, Medinat Ajayi, Abigail Baltazar, Davis Sharella, Nasra Hersi, Thuy Nguyen, Rugiatu Timbo, Ismail Jalloh, Susan Bryan, Patricia Clarke, Marcia Kerr, Fidelis Amedu, Maria BohoBonaba, Sarah Haque, Michelle Howson, Norbai Tambilawan, Soledad Yupanqui Estay, Hawanatu Bangura, Tseday Gideon, Damilola Jerome-oboh, Linda Tetteh, Chioma Nwagu, Viwoalo Agbaglah, Nona Narag, Mahima Zaveri, Maedhbh Ni Luanaigh, Peggy Keane, Aula Abbara, Olamide Dosekun, Mhairi Bolland, Adam Stafford, Dina Saleh, Rhianna Sheridan, Ella Davies, Kristi Sun, Mark Gilchrist, Priti Kukadia, Muhammed Embrahimsa, Christopher Chiu, Lauren Taylor, Charlotte Short, Jasmini Alagratnam, Iresh Jayaweera, Kavitha Gundugola, Lara V S Payne, Killian Quinn, Caoimhe Nic Fhogartaigh, Nivenjit Kaur, Salmaan Bholah, Kajann Kantha, Jonathan Youngs, Temi Lampejo, Nicholas Pitto, David S Lawrence, Holly Middleditch, Lourdes Dominguez-Dominguez, Ayoma Ratnappuli, Sara Al-Hashimi, Amelia Oliveira, Zoe Ottaway, Larissa Mulka, Anne M Neary, Michael R Downey, Danielle C Lucy, Craig I McCallum, Michael Beadsworth, Libuse Ratcliffe, Tom E Fletcher, Gerry Davies, Nicholas Wong, Stephen Aston, Thomas E Wingfield, Thomas Blanchard, Paul Hine, Susie Gould, Christopher Smith, Michael Abouyannis, Abolaji Atomode, James Cruise, Merna Samual, Nicola Scott, Vino Srirathan, Joseph Lewis, Lauren Richards, Mary-Ann Cummings, Emily Gillan, Rebecca Peers, Amy Tickle, Grace Keating, Tendi Chinyanda, Mav Sanchez, Daniel Harrison, null Hoyle, Ben Metcalfe, Jennifer Taylor, Nicky Johnson, Neil Kelle, Kirsty McDowell, Ian Richardson, Monette Saguidan, Nicky Farmer, Angella Gillespie, Shay Willoughby, Samantha Parker, Shamseena Avulan, Shazia Arif, Suzanne Marshall, David Carlisle, Mohsen Rezaei, Angela Booth, Joanne Watts, Lauren Tremarco, Priyanga Jeyanayagam, Odinaka Ubochi, Daniel Vagianos, Mark Richardson, Anthony Jarvis, Kyra Gow, Jade Walmsley, Adam O'keefe, Anna Smielewska, Mark Hopkins, Fatima Balane, Sarah Bradley, Tumena Corrah, Venus Daquiz, Christopher Dugan, Joshua Elliot, Fiona Foley, Dawn Friday, May Gamit, David Garner, Karishma Gokani, Laurence John, Deepa Joseph, Nuzhath Khan, Cherifer Mamuyac, Alastair McGregor, John McSorley, Victoria Parris, Luciana Rubinstein, Julian Rycroft, Kelcy Salinas, Jason Salinas, Jency Sebatian, Melanie Smith, Marina Tejero Garcia, Uchenna Ume, Margarete Vicentine, Gabriel Wallis, Alec Bonington, Alison Uriel, Andrew Ustianowski, Balazs Dancso, Celia Hogan, Clare van Halsema, F Javier Vilar, Karen Devine, Katherine Ajdukiewicz, Rajesh Rajendran, Samit Ghosh, Michael Riste, Nicholas Machin, Chitra Babu, Shazaad Ahmad, Dorcas Obeng, Farnaz Dave, Gavin Conolley, Joseph Thompson, Maya Tickell-Painter, Prasun Chakravorty, Rachel Pringle, Mohammad R Zafar, Sarah Lawrence, Amada Sanchez-Gonzalez, Cristina Fernandez, Lynsey Goodwin, David Carey, Molly Howarth-Maddison, Samuel Moody, Rebecca Upton, Christina Apthorp, Charlotte Murray, Kirstie Salthouse, Sabah Nadeem, Grant Ridley, Francesca White, Andrew Brown, Michael Lawless, Mohamed Mohamed, Robert Mulligan, Amy Belfield, Jacob Brolly, Maria Calderon, James Cheveau, Milo Cullinan, Sophie Garrad, Will Griffiths, Aidan Ireland, Peter Ireland, Charlotte Milne, Paul Nwajiugo, Bijan Ghavami-Kia, Chris Duncan, Adam Evans, Ewan Hunter, Ashley Price, Matthias Schmid, Uli Schwab, Yusri Taha, Brendan Payne, Ivo A M Elliott, Charles J Woodrow, Drosos E Karageorgopoulos, Peter J Davis, Emily Lord, Oliver J Bannister, Andrew B Dagens, Anne Tunbridge, Saher Choudry, Adam Telfer, Ihsan Jhibril, Syed N Atta, Ben Stone, Cariad Evans, Mike Ankcorn, Suha Akili, Mehmet Yavuz, Vicky Goodall, Sam Farrow, Georgina Mountford, Kate Beard, Julian Sutton, Tristan Clark, Annette Mason, Mike Vickers, Derek Macallan, Tihana Bicanic, Angela Houston, Cassie Pope, NgeeKeong Tan, Christopher Ward, Jonathan Cohen, Marieke Emonts-le Clercq, David Porter, Andrew Riordan, Ruchi Sinha, Elizabeth Whittaker
Publikováno v:
The Lancet Infectious Diseases. 23:589-597
Background:The scale of the 2022 global mpox (formerly known as monkeypox) outbreak has been unprecedented. In less than 6 months, non-endemic countries have reported more than 67 000 cases of a disease that had previously been rare outside of Afri
Autor:
Hannah Rafferty, Matthew J Murray, Jerry C H Tam, Alastair Macfarlane, Colette Smith, Sheila F Lumley, Sowsan Atabani, Jane A McKeating, Dinesh Sharma, Matthew Reeves, David Whitmore, Paul Griffiths
Publikováno v:
The Journal of Infectious Diseases. 226:357-365
Background Cytomegalovirus (CMV) is an important opportunistic pathogen after transplantation. Some virological variation in transplant recipients is explained by donor and recipient CMV serostatus, but not all. Circadian variability of herpesviruses
Autor:
Ashwini Kurshan, Luke B Snell, Lucie Prior, Jerry C H Tam, Carl Graham, Rajeni Thangarajah, Jonathan D Edgeworth, Gaia Nebbia, Katie J Doores
Publikováno v:
Oxford Open Immunology. 4
Neutralizing monoclonal antibodies (mAbs) targeting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Spike glycoprotein have been developed for the treatment of COVID-19. Whilst antibody therapy has been shown to reduce the risk of COVID-
Autor:
Luke Blagdon Snell, Prijay Bakrania, Tom G S Williams, Jerry C H Tam, Dayana Da Silva Fontoura, Emily Shaw, Anna Daunt, Jonathan D Edgeworth, Carolyn J Hemsley, Paul Fields, Sangita Agarwal, Boris Lams, Helen Cahill, Iain Milligan, Alina Botgros, Gaia Nebbia, Sam T Douthwaite, Emma Aarons
Publikováno v:
Snell, L B, Bakrania, P, Williams, T G S, Tam, J, Da Silva Fontoura, D, Shaw, E, Daunt, A, Edgeworth, J, Hemsley, C J, Fields, P, Agarwal, S, Lams, B, Cahill, H, Milligan, I, Botgros, A, Nebbia, G, Douthwaite, S & Aarons, E J 2022, ' Severe COVID-19 caused by persistent SARS-CoV-2 infection successfully treated with dual direct acting antivirals ', preprint .
We report the successful use of combination therapy with two direct acting antivirals for treatment of chronic COVID-19. An immunocompromised 60 year old male with persistent SARS-CoV-2 infection over 4 months had chronic, progressive COVID-19 requir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab394ef4d4020b29733538dd129f31a7
https://kclpure.kcl.ac.uk/ws/files/186271727/Severe_COVID_19_caused_by_SNELL_2022_GREEN_AAM.pdf
https://kclpure.kcl.ac.uk/ws/files/186271727/Severe_COVID_19_caused_by_SNELL_2022_GREEN_AAM.pdf
Autor:
Aatish Patel, Julia Bilinska, Jerry C H Tam, Dayana Da Silva Fontoura, Claire Y Mason, Anna Daunt, Luke B Snell, Jamie Murphy, Jack Potter, Cecilia Tuudah, Rohan Sundramoorthi, Movin Abeywickrema, Caitlin Pley, Vasanth Naidu, Gaia Nebbia, Emma Aarons, Alina Botgros, Sam T Douthwaite, Claire van Nispen tot Pannerden, Helen Winslow, Aisling Brown, Daniella Chilton, Achyuta Nori
Publikováno v:
Patel, A, Bilinska, J, Tam, J, Da Silva Fontoura, D, Mason, C, Daunt, A, Snell, L B, Murphy, J, Potter, J, Tuudah, C, Sundramoorthi, R, Abeywickrema, M, Pley, C, Naidu, V, Nebbia, G, Aarons, E, Botgros, A, Douthwaite, S, van Nispen tot Pannerden, C, Winslow, H, Brown, A, Chilton, D & Nori, A 2022, ' Clinical features and novel presentations of human monkeypox in a central London centre during the 2022 outbreak: descriptive case series ', BMJ, vol. 378, e072410 . https://doi.org/10.1136/bmj-2022-072410
ObjectiveTo characterise the clinical features of monkeypox infection in humans.DesignDescriptive case series.SettingA regional high consequences infectious disease centre with associated primary and secondary care referrals, and affiliated sexual he
Publikováno v:
Clinical Infection in Practice
Clinical Infection in Practice, Vol 9, Iss, Pp 100059-(2021)
Clinical Infection in Practice, Vol 9, Iss, Pp 100059-(2021)
Highlights • Thrombosis associated with COVID-19 can occur at diverse sites. • Arterial as well as venous thrombosis can complicate COVID-19. • Thromboprophylaxis is advised for COVID-19 patients with thrombosis risk factors. • More evidence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4135b2b251e0da3980572e2ab3f3e0ab
https://doi.org/10.1016/j.clinpr.2020.100059
https://doi.org/10.1016/j.clinpr.2020.100059
Autor:
Jerry C. H. Tam, David A. Jacques
Publikováno v:
Journal of Leukocyte Biology
Review of how cells can sense their own infection, and their attempts to eliminate pathogens.
Historically, once a cell became infected, it was considered to be beyond all help. By this stage, the invading pathogen had breached the innate defens
Historically, once a cell became infected, it was considered to be beyond all help. By this stage, the invading pathogen had breached the innate defens