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pro vyhledávání: '"Jerry Andrew Taylor"'
Autor:
Joe Clemas, Jerry Andrew Taylor, Feroze Ujjainwalla, Jim Tata, Doris F. Cully, Tom Wisniewski, Wei Tang, Charlene Bopp, Clare London, Andreas Verras, Scott B. Hoyt, Andrea Sok, Elaine Tung, Douglas J. MacNeil, Gaochao Zhou, Amjad Ali, Qing Chen, Gino Salituro, Yusheng Xiong, Daniel R. McMasters, Mary Struthers, Ning Ren, Ruth A. Duffy
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 27:2384-2388
We report the discovery and hit-to-lead optimization of a structurally novel indazole series of CYP11B2 inhibitors. Benchmark compound 34 from this series displays potent inhibition of CYP11B2, high selectivity versus related steroidal and hepatic CY
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8f9a114775b2eff2c4ce3ec96aa4668
https://doi.org/10.1016/j.bmcl.2017.04.021
https://doi.org/10.1016/j.bmcl.2017.04.021
