Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Jerry A Stitzel"'
Autor:
Luke M Evans, Christopher H Arehart, Andrew D Grotzinger, Travis J Mize, Maizy S Brasher, Jerry A Stitzel, Marissa A Ehringer, Charles A Hoeffer
Publikováno v:
PLoS Genetics, Vol 19, Iss 5, p e1010693 (2023)
It remains unknown to what extent gene-gene interactions contribute to complex traits. Here, we introduce a new approach using predicted gene expression to perform exhaustive transcriptome-wide interaction studies (TWISs) for multiple traits across a
Externí odkaz:
https://doaj.org/article/7d8582f0fd6c466aa6c491b1ac55b416
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63699 (2013)
Common genetic factors strongly contribute to both nicotine, the main addictive component of tobacco, and alcohol use. Several lines of evidence suggest nicotinic acetylcholine receptors as common sites of action for nicotine and alcohol. Specificall
Externí odkaz:
https://doaj.org/article/c4cd5f153a284934a89657fdccbd91d0
Autor:
Helen Wong, Jordan M. Buck, Curtis Borski, Jessica T. Pafford, Bailey N. Keller, Ryan A. Milstead, Jessica L. Hanson, Jerry A. Stitzel, Charles A. Hoeffer
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 14, Iss 1, Pp 1-23 (2022)
Abstract Background Regulator of calcineurin 1 (RCAN1) is overexpressed in Down syndrome (DS), but RCAN1 levels are also increased in Alzheimer’s disease (AD) and normal aging. AD is highly comorbid among individuals with DS and is characterized in
Externí odkaz:
https://doaj.org/article/5bb79d8910314ac5a630b405cad468f8
Autor:
Julie Routhier, Stéphanie Pons, Mohamed Lamine Freidja, Véronique Dalstein, Jérôme Cutrona, Antoine Jonquet, Nathalie Lalun, Jean-Claude Mérol, Mark Lathrop, Jerry A. Stitzel, Gwenola Kervoaze, Muriel Pichavant, Philippe Gosset, Jean-Marie Tournier, Philippe Birembaut, Valérian Dormoy, Uwe Maskos
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Human polymorphisms in nicotinic acetylcholine receptor genes have been linked to both smoking and lung diseases like Chronic Obstructive Pulmonary Disease (COPD) or lung cancer. Here the authors identify a direct role for a human coding polymorphism
Externí odkaz:
https://doaj.org/article/beb4aa7e77234ba9bf33270113914c9a
Publikováno v:
Epigenetics & Chromatin, Vol 13, Iss 1, Pp 1-15 (2020)
Abstract Background Maternal smoking of traditional or electronic cigarettes during pregnancy, which constitutes developmental nicotine exposure (DNE), heightens the risk of neurodevelopmental disorders including ADHD, autism, and schizophrenia in ch
Externí odkaz:
https://doaj.org/article/98157f68141d42a4a5cc0e4b0d8280f8
Autor:
Erin Meyers, Zachary Werner, David Wichman, Hunter L. Mathews, Richard A. Radcliffe, Joseph H. Nadeau, Jerry A. Stitzel
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
The gene CHRNA5 is strongly associated with the level of nicotine consumption in humans and manipulation of the expression or function of Chrna5 similarly alters nicotine consumption in rodents. In both humans and rodents, reduced or complete loss of
Externí odkaz:
https://doaj.org/article/047a09140d1e4fe3a9f18115d9175c50
Autor:
Travis J Mize, Scott A Funkhouser, Jordan M Buck, Jerry A Stitzel, Marissa A Ehringer, Luke M Evans
Publikováno v:
Nicotine & Tobacco Research. 25:1030-1038
Introduction Smoking behaviors are partly heritable, yet the genetic and environmental mechanisms underlying smoking phenotypes are not fully understood. Developmental nicotine exposure (DNE) is a significant risk factor for smoking and leads to gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5924b793534671c8f509796f0be5cd80
https://doi.org/10.1093/ntr/ntac269
https://doi.org/10.1093/ntr/ntac269
Autor:
Luke M. Evans, Christopher H. Arehart, Andrew D. Grotzinger, Travis J. Mize, Maizy S. Brasher, Jerry A. Stitzel, Marissa A. Ehringer, Charles A. Hoeffer
It remains unknown to what extent gene-gene interactions contribute to complex traits. Here, we introduce a new approach using predicted gene expression to perform exhaustive transcriptome-wide interaction studies (TWISs) for multiple traits across a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::588d6940f3afc22727ff4d0e65e3f3f2
https://doi.org/10.1101/2022.08.16.504187
https://doi.org/10.1101/2022.08.16.504187
Autor:
Bailey N. Keller, Jessica Pafford, Curtis Borski, Charles A. Hoeffer, Jordan M. Buck, Jerry A. Stitzel, Helen Wong
Background: Regulator of calcineurin 1 (RCAN1) is overexpressed in Down syndrome (DS), but RCAN1 levels are also increased in Alzheimer's disease (AD) and normal aging. AD is highly comorbid among individuals with DS and is characterized in part by p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::666fa1707857566b5c3ef6fb8f46f55d
https://doi.org/10.21203/rs.3.rs-1032228/v1
https://doi.org/10.21203/rs.3.rs-1032228/v1
Autor:
Helen Wong, Jordan M. Buck, Curtis Borski, Jessica T. Pafford, Bailey N. Keller, Ryan A. Milstead, Jessica L. Hanson, Jerry A. Stitzel, Charles A. Hoeffer
Publikováno v:
Journal of neurodevelopmental disorders. 14(1)
Background Regulator of calcineurin 1 (RCAN1) is overexpressed in Down syndrome (DS), but RCAN1 levels are also increased in Alzheimer’s disease (AD) and normal aging. AD is highly comorbid among individuals with DS and is characterized in part by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::742dc474652a106ed39150cf078a2f1c
https://pubmed.ncbi.nlm.nih.gov/35610565
https://pubmed.ncbi.nlm.nih.gov/35610565