Výsledky vyhledávání - "Jerry A, Katzmann"

Risk of MGUS in Relatives of Multiple Myeloma Cases by Clinical and Tumor Characteristics

Autor: Aaron D. Norman, Abdul Rishi, Susan L. Slager, Shaji Kumar, Celine M. Vachon, Dirk R. Larson, Alexandra J. Greenberg, Alyssa I. Clay-Gilmour, Jerry A. Katzmann, S. Vincent Rajkumar, David L. Murray, Megan M. O’Byrne, Robert A. Kyle

We and others have shown increased risk of monoclonal gammopathy of undetermined significance (MGUS) in first-degree relatives of patients with multiple myeloma (MM). Whether familial risk of MGUS differs by the MM proband's age at onset, tumor or cl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::329d44b6ef56c0c517a19a4ef9c83f55
https://europepmc.org/articles/PMC6371786/

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Elevation of Serum Immunoglobulin Free Light Chains During the Preclinical Period of Rheumatoid Arthritis

Autor: S. Vincent Rajkumar, Eric L. Matteson, John M. Davis, Dirk R. Larson, Jerry A. Katzmann, Robert A. Kyle, Terry M. Therneau, Xiaoli Deng, Cynthia S. Crowson, Angela Dispenzieri, Sherine E. Gabriel

Publikováno v: The Journal of Rheumatology. 42:181-187

Objective.Immunoglobulin free light chains (FLC) represent biomarkers of B cell activity in rheumatoid arthritis (RA) and are associated with all-cause mortality in the general population. Our objective was to evaluate the relationships of serum FLC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::af547afed43d2ab8a2ea9a24b46adead
https://doi.org/10.3899/jrheum.140543

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Elevated monoclonal and polyclonal serum immunoglobulin free light chain as prognostic factors in B- and T-cell non-Hodgkin lymphoma

Autor: Mamta Gupta, Brian K. Link, Svetomir N. Markovic, Yi Lin, Grzegorz S. Nowakowski, David J. Inwards, Thomas M. Habermann, Joseph P. Colgan, Stephen M. Ansell, Carrie A. Thompson, Matthew J. Maurer, Thomas E. Witzig, Patrick B. Johnston, Luis F. Porrata, Jerry A. Katzmann, James R. Cerhan, Ivana N. Micallef

Publikováno v: American Journal of Hematology. 89:1116-1120

The serum immunoglobulin free light chain (FLC) assay quantitates free kappa (κ) and lambda (λ) light chains. FLC elevations in patients with diffuse large B-cell lymphoma (DLBCL), Hodgkin lymphoma (HL), and chronic lymphocytic leukemia (CLL) are a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::786f68d43388f34d9c4a0c8d4f352f87
https://doi.org/10.1002/ajh.23839

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Phenotyping Polyclonal Kappa and Lambda Light Chain Molecular Mass Distributions in Patient Serum Using Mass Spectrometry

Autor: David L. Murray, Maria Alice V. Willrich, David R. Barnidge, Surendra Dasari, Renee C. Tschumper, Diane F. Jelinek, Melissa R. Snyder, Marina Ramirez-Alvarado, Adrian Fontan, Jerry A. Katzmann, Angela Dispenzieri

Publikováno v: Journal of Proteome Research. 13:5198-5205

We previously described a microLC-ESI-Q-TOF MS method for identifying monoclonal immunoglobulins in serum and then tracking them over time using their accurate molecular mass. Here we demonstrate how the same methodology can be used to identify and c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d38c7bb8eeed1c8e0e3878e2cc0e9d2
https://doi.org/10.1021/pr5005967

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Monitoring M-Proteins in Patients with Multiple Myeloma Using Heavy-Chain Variable Region Clonotypic Peptides and LC–MS/MS

Autor: David L. Murray, Renee C. Tschumper, David R. Barnidge, Jerry A. Katzmann, Diane F. Jelinek, Angela Dispenzieri, Melissa R. Snyder, Jason D. Theis

Publikováno v: Journal of Proteome Research. 13:1905-1910

Multiple myeloma is a disease characterized by a clonal expansion of plasma cells that secrete a monoclonal immunoglobulin also referred to as an M-protein. In the clinical laboratory, protein electrophoresis (PEL), immunofixation electrophoresis (IF

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b01cb2d8fe0b6b84ceb51ffeccf96177
https://doi.org/10.1021/pr5000544

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Elevated serum monoclonal and polyclonal free light chains and interferon inducible protein-10 predicts inferior prognosis in untreated diffuse large B-cell lymphoma

Autor: Mary Stenson, Brian K. Link, Thomas E. Witzig, Mamta Gupta, Cristine Allmer, William R. Macon, Jerry A. Katzmann, Matthew J. Maurer

Publikováno v: American Journal of Hematology. 89:417-422

The detection of serum free light (FLC) is useful in the diagnosis of several hematological diseases. The role and biological relevance of monoclonal or polyclonal FLC elevations in predicting long-term outcome in diffuse large B-cell lymphoma (DLBCL

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::12f85ca665db1d9ca57206d7ccc955e7
https://doi.org/10.1002/ajh.23658

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Racial disparities in the prevalence of monoclonal gammopathies: a population-based study of 12 482 persons from the National Health and Nutritional Examination Survey

Autor: G M McQuillan, Neil E. Caporaso, L. J. Melton, Shaji Kumar, I Ahmadizadeh, B I Graubard, R Costello, Neha Korde, Robert A. Kyle, Mark Roschewski, Angela Dispenzieri, Terry M. Therneau, Alexandra J. Greenberg, Raynell J. Clark, Jerry A. Katzmann, S V Rajkumar, Ola Landgren

Publikováno v: Leukemia. 28:1537-1542

Multiple myeloma (MM) incidence is markedly higher in blacks compared with whites, which may be related to a higher prevalence of monoclonal gammopathy of undetermined significance (MGUS). Our objective was to define the prevalence and risk factors o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::600f9ec1df3f7c594b3973c6789a4248
https://doi.org/10.1038/leu.2014.34

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Restricted IgG-Kappa and Free Alpha-Heavy-Chain Bands in an Asymptomatic 62-Year-Old Man

Autor: Lawrence M. Silverman, Jerry A. Katzmann, David E. Bruns, David L. Murray, Min Yu

Publikováno v: Clinical chemistry. 64(2)

A 62-year-old Virginia man in good health was found on routine testing to have a decreased platelet count of 124k/μL (reference interval: 150–450k/μL). There was no evidence of bruising or bleeding, and there was no family history of thrombocytop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc924fa689d5e2f639777d5330440e2b
https://pubmed.ncbi.nlm.nih.gov/29378744

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Suppression of uninvolved immunoglobulins defined by heavy/light chain pair suppression is a risk factor for progression of MGUS

Autor: Joanne T. Benson, L. J. Melton, Ola Landgren, Dirk R. Larson, S V Rajkumar, Robert A. Kyle, Shaji Kumar, James R. Cerhan, Raynell J. Clark, Jerry A. Katzmann, Terry M. Therneau, Angela Dispenzieri, Colin L. Colby, Arthur R. Bradwell

Publikováno v: Leukemia. 27:208-212

We hypothesized that the suppression of uninvolved immunoglobulin in monoclonal gammopathy of undetermined significance (MGUS) as detected by suppression of the isotype-specific heavy and light chain (HLC-pair suppression) increases the risk of progr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7162f0d2453fec35dc313e18110eb4e
https://doi.org/10.1038/leu.2012.189

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