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pro vyhledávání: '"Jerrod L. Wigal"'
Autor:
Jan Pohl, Peter E. Jensen, Dominique A. Weber, Jerrod L. Wigal, Antoine Attinger, Ellis L. Reinherz, Mitchell Kronenberg, Hilde Cheroutre, Yi Xiong, Christopher C. Kemball
Publikováno v:
The Journal of Immunology. 169:5708-5714
The nonclassical class I molecule, thymic leukemia (TL), has been shown to be expressed on intestinal epithelial cells and to interact with CD8+ intraepithelial T lymphocytes. We generated recombinant soluble TL (T18d) H chains in bacteria as inclusi
Publikováno v:
The Journal of Immunology. 167:5167-5174
HLA-DM catalyzes peptide loading and exchange reactions by MHC class II molecules. Soluble recombinant DM, lacking transmembrane and cytoplasmic domains, was observed to have 200- to 400-fold less activity compared with the full-length protein in ass