Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jerrica L. Breindel"'
Autor:
Jerrica L. Breindel, Adam Skibinski, Maja Sedic, Ania Wronski-Campos, Wenhui Zhou, Patricia J. Keller, Joslyn Mills, James Bradner, Tamer Onder, Charlotte Kuperwasser
Publikováno v:
Stem Cell Reports, Vol 9, Iss 3, Pp 943-955 (2017)
Organogenesis and tissue development occur through sequential stepwise processes leading to increased lineage restriction and loss of pluripotency. An exception to this appears in the adult human breast, where rare variant epithelial cells exhibit pl
Externí odkaz:
https://doaj.org/article/15112164c4b44467a40b1d0c89dc317d
Autor:
Kayla M. Gross, Wenhui Zhou, Jerrica L. Breindel, Jian Ouyang, Dexter X. Jin, Ethan S. Sokol, Piyush B. Gupta, Kathryn Huber, Lee Zou, Charlotte Kuperwasser
Publikováno v:
Cell Reports, Vol 28, Iss 2, Pp 394-407.e6 (2019)
Summary: DNA damage activates checkpoints that limit the replicative potential of stem cells, including differentiation. These checkpoints protect against cancer development but also promote tissue aging. Because mice lacking Slug/Snai2 exhibit limit
Externí odkaz:
https://doaj.org/article/00f5bc3ed8f84bf6aea39db96aacf13a
Autor:
Adam Skibinski, Jerrica L. Breindel, Aleix Prat, Patricia Galván, Elizabeth Smith, Andreas Rolfs, Piyush B. Gupta, Joshua LaBaer, Charlotte Kuperwasser
Publikováno v:
Cell Reports, Vol 6, Iss 6, Pp 1059-1072 (2014)
Lineage-committed cells of many tissues exhibit substantial plasticity in contexts such as wound healing and tumorigenesis, but the regulation of this process is not well understood. We identified the Hippo transducer WWTR1/TAZ in a screen of transcr
Externí odkaz:
https://doaj.org/article/7fb373accf174eabb69d43e14236433c
Autor:
David F. Stern, Don X. Nguyen, Minghui Zhao, Elizabeth P. Cowell, Jonathan W. Haskins, Jerrica L. Breindel
PDF file - 2053K, MET knockdown and cell migration in PC9 and PC9-BrM3 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dacfa9ddc607dfbaf66fcf0d7de673d4
https://doi.org/10.1158/0008-5472.22401110.v1
https://doi.org/10.1158/0008-5472.22401110.v1
Autor:
David F. Stern, Don X. Nguyen, Minghui Zhao, Elizabeth P. Cowell, Jonathan W. Haskins, Jerrica L. Breindel
PDF file - 1952K, EGFR activation of MET in 32D cells is dependent on transcription, translation, and intermediary signaling.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::240b10bb1d5294ac42eaee352fa2e806
https://doi.org/10.1158/0008-5472.22401119.v1
https://doi.org/10.1158/0008-5472.22401119.v1
Autor:
David F. Stern, Don X. Nguyen, Minghui Zhao, Elizabeth P. Cowell, Jonathan W. Haskins, Jerrica L. Breindel
MET amplification as a mechanism of acquired resistance to EGF receptor (EGFR)-targeted therapies in non–small cell lung carcinoma (NSCLC) led to investigation of novel combinations of EGFR and MET kinase inhibitors. However, promiscuous interactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56d51cea34b7c542c554b26d3934766d
https://doi.org/10.1158/0008-5472.c.6505763
https://doi.org/10.1158/0008-5472.c.6505763
Autor:
David F. Stern, Don X. Nguyen, Minghui Zhao, Elizabeth P. Cowell, Jonathan W. Haskins, Jerrica L. Breindel
PDF file - 886K, MET promotes EGF-induced migration and invasion of NSCLC cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a6b5ff7a82cd4c2dcc39c8b69b40836
https://doi.org/10.1158/0008-5472.22401113
https://doi.org/10.1158/0008-5472.22401113
Autor:
David F. Stern, Don X. Nguyen, Minghui Zhao, Elizabeth P. Cowell, Jonathan W. Haskins, Jerrica L. Breindel
PDF file - 1350K, Ligand-dependent phosphorylation of MET and EGFR in 32D cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::991b0aeff61a051b3d8b6cad9a991663
https://doi.org/10.1158/0008-5472.22401125.v1
https://doi.org/10.1158/0008-5472.22401125.v1
Autor:
David F. Stern, Don X. Nguyen, Minghui Zhao, Elizabeth P. Cowell, Jonathan W. Haskins, Jerrica L. Breindel
PDF file - 502K, EGFR modulates MET phosphorylation, protein, and mRNA levels in PC9 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dee09a1b2fbf8e45c69d8029bc06096
https://doi.org/10.1158/0008-5472.22401116
https://doi.org/10.1158/0008-5472.22401116