Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jeromy J Digiacomo"'
Autor:
Timothy N. Phoenix, Pratiti Bandopadhayay, David T.W. Jones, Henry Long, Claudia L. Kleinman, Volker Hovestadt, Keith L. Ligon, Stefan M. Pfister, Olaf Witt, Nada Jabado, François Aguet, Gad Getz, James M. McFarland, Jinghui Zhang, Suzanne J. Baker, Stefan Bielack, Michaela Nathrath, Christof M. Kramm, Gnana Prakash Balasubramanian, Natalie Jager, Uta Dirksen, David S. Ziegler, Maria Tsoli, J'Ya Hunter, Dana Novikov, Rushil Kumbhani, Jeromy J. Digiacomo, Madison S. Chacon, Elizabeth M. Gonzalez, Sophie D. Lu, Kevin N. Zhou, Sarah E. Dixon-Clarke, Alexandra L. Condurat, Xiaolong Chen, Audrey Baguette, Cecilia Sousa, Jayne Vogelzang, Kristine Pelton, Alexander Crane, Frank P.B. Dubois, Sudeepa Syamala, Ningxuan Zhou, Xin Wei, Phonepasong Arounleut, David W. Wu, Smruti Patel, Dayle K. Wang, Paloma Cejas, Jessica W. Tsai
Forkhead box R2 (FOXR2) is a forkhead transcription factor located on the X chromosome whose expression is normally restricted to the testis. In this study, we performed a pan-cancer analysis of FOXR2 activation across more than 10,000 adult and pedi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::741da86f253c6e42c0401531e9509b90
https://doi.org/10.1158/0008-5472.c.6514136.v1
https://doi.org/10.1158/0008-5472.c.6514136.v1
Autor:
Timothy N. Phoenix, Pratiti Bandopadhayay, David T.W. Jones, Henry Long, Claudia L. Kleinman, Volker Hovestadt, Keith L. Ligon, Stefan M. Pfister, Olaf Witt, Nada Jabado, François Aguet, Gad Getz, James M. McFarland, Jinghui Zhang, Suzanne J. Baker, Stefan Bielack, Michaela Nathrath, Christof M. Kramm, Gnana Prakash Balasubramanian, Natalie Jager, Uta Dirksen, David S. Ziegler, Maria Tsoli, J'Ya Hunter, Dana Novikov, Rushil Kumbhani, Jeromy J. Digiacomo, Madison S. Chacon, Elizabeth M. Gonzalez, Sophie D. Lu, Kevin N. Zhou, Sarah E. Dixon-Clarke, Alexandra L. Condurat, Xiaolong Chen, Audrey Baguette, Cecilia Sousa, Jayne Vogelzang, Kristine Pelton, Alexander Crane, Frank P.B. Dubois, Sudeepa Syamala, Ningxuan Zhou, Xin Wei, Phonepasong Arounleut, David W. Wu, Smruti Patel, Dayle K. Wang, Paloma Cejas, Jessica W. Tsai
Supplementary Figure from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08c77d20498973705d006fee266ee01a
https://doi.org/10.1158/0008-5472.22432439.v1
https://doi.org/10.1158/0008-5472.22432439.v1
Autor:
Timothy N. Phoenix, Pratiti Bandopadhayay, David T.W. Jones, Henry Long, Claudia L. Kleinman, Volker Hovestadt, Keith L. Ligon, Stefan M. Pfister, Olaf Witt, Nada Jabado, François Aguet, Gad Getz, James M. McFarland, Jinghui Zhang, Suzanne J. Baker, Stefan Bielack, Michaela Nathrath, Christof M. Kramm, Gnana Prakash Balasubramanian, Natalie Jager, Uta Dirksen, David S. Ziegler, Maria Tsoli, J'Ya Hunter, Dana Novikov, Rushil Kumbhani, Jeromy J. Digiacomo, Madison S. Chacon, Elizabeth M. Gonzalez, Sophie D. Lu, Kevin N. Zhou, Sarah E. Dixon-Clarke, Alexandra L. Condurat, Xiaolong Chen, Audrey Baguette, Cecilia Sousa, Jayne Vogelzang, Kristine Pelton, Alexander Crane, Frank P.B. Dubois, Sudeepa Syamala, Ningxuan Zhou, Xin Wei, Phonepasong Arounleut, David W. Wu, Smruti Patel, Dayle K. Wang, Paloma Cejas, Jessica W. Tsai
Supplementary Table from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010b86034115df2220900de572ba0818
https://doi.org/10.1158/0008-5472.22432385
https://doi.org/10.1158/0008-5472.22432385
FOXR2 is an epigenetically regulated pan-cancer oncogene that activates ETS transcriptional circuits
Autor:
Jessica W. Tsai, Paloma Cejas, Dayle K. Wang, Smruti Patel, David W. Wu, Phonepasong Arounleut, Xin Wei, Ningxuan Zhou, Sudeepa Syamala, Frank P.B. Dubois, Alexander Crane, Kristine Pelton, Jayne Vogelzang, Cecilia Sousa, Audrey Baguette, Xiaolong Chen, Alexandra L. Condurat, Sarah E. Dixon-Clarke, Kevin N. Zhou, Sophie D. Lu, Elizabeth M. Gonzalez, Madison S. Chacon, Jeromy J. Digiacomo, Rushil Kumbhani, Dana Novikov, J'Ya Hunter, Maria Tsoli, David S. Ziegler, Uta Dirksen, Natalie Jager, Gnana Prakash Balasubramanian, Christof M. Kramm, Michaela Nathrath, Stefan Bielack, Suzanne J. Baker, Jinghui Zhang, James M. McFarland, Gad Getz, François Aguet, Nada Jabado, Olaf Witt, Stefan M. Pfister, Keith L. Ligon, Volker Hovestadt, Claudia L. Kleinman, Henry Long, David T.W. Jones, Pratiti Bandopadhayay, Timothy N. Phoenix
Publikováno v:
Cancer Res
Forkhead box R2 (FOXR2) is a forkhead transcription factor located on the X chromosome whose expression is normally restricted to the testis. In this study, we performed a pan-cancer analysis of FOXR2 activation across more than 10,000 adult and pedi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b04fde1eafeb27aba2cd478be2c63a8
https://europepmc.org/articles/PMC9437574/
https://europepmc.org/articles/PMC9437574/
Autor:
Jessica W. Tsai, Paloma Cejas, Marissa Coppola, Dayle K. Wang, Smruti Patel, David W. Wu, Phonepasong Arounleut, Xin Wei, Ningxuan Zhou, Sudeepa Syamala, Frank P. Dubois, Kristine Pelton, Jayne Vogelzang, Cecilia Sousa, Audrey Baguette, Xiaolong Chen, Alexandra L. Condurat, Sarah E. Dixon-Clarke, Annarah Charles, Kevin N. Zhou, Sophie D. Lu, Elizabeth M. Gonzalez, Madison S. Chacon, Jeromy J. Digiacomo, Rushil Kumbhani, Dana Novikov, Maria Tsoli, David S. Ziegler, Uta Dirksen, Natalie Jager, Gnana Prakash Balasubramanian, Christof M. Kramm, Michaela Nathrath, Stefan Bielack, Suzanne J. Baker, Jinghui Zhang, James M. McFarland, Gad Getz, Francois Aguet, Nada Jabado, Olaf Witt, Stefan M. Pfister, Keith L. Ligon, Volker Hovestadt, Claudia Kleinman, Henry Long, David T. Jones, Pratiti Bandopadhayay, Timothy N. Phoenix
Publikováno v:
Cancer Research. 83:3562-3562
Background: Diffuse midline gliomas (DMGs) are a universally fatal brain tumor of childhood. While histone mutations are a critical tumor initiating event, they are insufficient to drive gliomagenesis. Histone mutations co-occur with somatic alterati
Autor:
Jessica W Tsai, Paloma Cejas, Dayle K Wang, Smruti Patel, David W Wu, Phonepasong Arounleut, Xin Wei, Ningxuan Zhou, Sudeepa Syamala, Frank P B Dubois, Alexander Crane, Kristine Pelton, Jayne Vogelzang, Cecilia Sousa, Audrey Baguette, Xiaolong Chen, Alexandra L Condurat, Sarah E Dixon-Clarke, Kevin N Zhou, Sophie D Lu, Elizabeth M Gonzalez, Madison S Chacon, Jeromy J Digiacomo, Rushil Kumbhani, Dana Novikov, J'Ya Hunter, Maria Tsoli, David S Ziegler, Uta Dirksen, Natalie Jager, Gnana Prakash Balasubramanian, Christof M Kramm, Michaela Nathrath, Stefan Bielack, Suzanne J Baker, Jinghui Zhang, James M McFarland, Gad Getz, Francois Aguet, Nada Jabado, Olaf Witt, Stefan M Pfister, Keith L Ligon, Claudia L Kleinman, Henry Long, David T W Jones, Pratiti Bandopadhayay, Timothy N Phoenix
BACKGROUND: Understanding how aberrant transcription factors (TFs) hijack normal development to induce oncogenesis is a critical question in oncology. Forkhead box (FOX) proteins are a superfamily of transcriptional regulators characterized by a fork
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07d62d7fc7e751a4d28899955a247a5d
Autor:
Jessica W. Tsai, Paloma Cejas, Dayle K. Wang, Smruti Patel, David W. Wu, Phonepasong Arounleut, Xin Wei, Ningxuan Zhou, Sudeepa Syamala, Frank P. Dubois, Kristine Pelton, Jayne Vogelzang, Cecilia Sousa, Audrey Baguette, Xiaolong Chen, Alexandra L. Condurat, Sarah E. Dixon-Clarke, Kevin N. Zhou, Sophie D. Lu, Elizabeth M. Gonzalez, Madison S. Chacon, Jeromy J. Digiacomo, Rushil Kumbhani, Dana Novikov, J'Ya Hunter, Maria Tsoli, David S. Ziegler, Uta Dirksen, Natalie Jager, Gnana Prakash Balasubramanian, Christof M. Kramm, Michaela Nathrath, Stefan Bielack, Suzanne J. Baker, Jinghui Zhang, James M. McFarland, Gad Getz, Francois Aguet, Nada Jabado, Olaf Witt, Stefan M. Pfister, Keith L. Ligon, Claudia Kleinman, Henry Long, David T. Jones, Pratiti Bandopadhayay, Timothy N. Phoenix
Publikováno v:
Cancer Research. 82:5730-5730
Background: Understanding how aberrant transcription factors (TFs) hijack normal development to induce oncogenesis is a critical question in oncology. Forkhead box (FOX) proteins are a superfamily of transcriptional regulators characterized by a fork
Autor:
Khadka P; Department of Cancer Biology, Dana Farber Cancer Institute, Boston, MA, 02215, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Harvard Biological and Biomedical Sciences PhD Program, Harvard University, Cambridge, MA, 02138, USA., Reitman ZJ; Department of Radiation Oncology, Duke University, Durham, NC, 27710, USA.; Duke Cancer Institute, Duke University, Durham, NC, 27710, USA.; The Preston Robert Tisch Brain Tumor Center at Duke, Duke University, Durham, NC, 27710, USA., Lu S; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, 02215, USA., Buchan G; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, 02215, USA., Gionet G; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, 02215, USA., Dubois F; Department of Cancer Biology, Dana Farber Cancer Institute, Boston, MA, 02215, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Carvalho DM; Division of Molecular Pathology, Institute of Cancer Research, London, UK., Shih J; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Zhang S; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Greenwald NF; Department of Cancer Biology, Dana Farber Cancer Institute, Boston, MA, 02215, USA., Zack T; Department of Cancer Biology, Dana Farber Cancer Institute, Boston, MA, 02215, USA., Shapira O; Department of Cancer Biology, Dana Farber Cancer Institute, Boston, MA, 02215, USA., Pelton K; Department of Oncologic Pathology, Dana Farber Cancer Institute, Boston, MA, 02215, USA., Hartley R; Division of Pharmaceutical Sciences, James L. Winkle College of Pharmacy, University of Cincinnati, Cincinnati, OH, 45267, USA., Bear H; Research in Patient Services, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45267, USA., Georgis Y; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, 02215, USA., Jarmale S; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, 02215, USA., Melanson R; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Bonanno K; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Schoolcraft K; Department of Oncologic Pathology, Dana Farber Cancer Institute, Boston, MA, 02215, USA., Miller PG; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA., Condurat AL; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, 02215, USA., Gonzalez EM; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, 02215, USA., Qian K; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, 02215, USA., Morin E; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, 02215, USA., Langhnoja J; Division of Pharmaceutical Sciences, James L. Winkle College of Pharmacy, University of Cincinnati, Cincinnati, OH, 45267, USA., Lupien LE; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, 02215, USA., Rendo V; Department of Cancer Biology, Dana Farber Cancer Institute, Boston, MA, 02215, USA., Digiacomo J; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, 02215, USA., Wang D; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, 02215, USA., Zhou K; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, 02215, USA., Kumbhani R; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, 02215, USA., Guerra Garcia ME; Duke Cancer Institute, Duke University, Durham, NC, 27710, USA., Sinai CE; Department of Oncologic Pathology, Dana Farber Cancer Institute, Boston, MA, 02215, USA., Becker S; Department of Oncologic Pathology, Dana Farber Cancer Institute, Boston, MA, 02215, USA., Schneider R; Department of Oncologic Pathology, Dana Farber Cancer Institute, Boston, MA, 02215, USA., Vogelzang J; Department of Oncologic Pathology, Dana Farber Cancer Institute, Boston, MA, 02215, USA., Krug K; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Goodale A; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Abid T; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Kalani Z; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Piccioni F; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Beroukhim R; Department of Cancer Biology, Dana Farber Cancer Institute, Boston, MA, 02215, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Persky NS; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Root DE; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Carcaboso AM; Department of Pediatric Hematology and Oncology, Hospital Sant Joan de Deu, Institut de Recerca Sant Joan de Deu, Barcelona, 08950, Spain., Ebert BL; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, 20815, USA., Fuller C; Department of Pathology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45267, USA., Babur O; College of Science and Mathematics, University of Massachusetts Boston, Boston, MA, 02125, USA., Kieran MW; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, 02215, USA.; Bristol Myers Squibb, Boston, Devens, MA, 01434, USA., Jones C; Division of Molecular Pathology, Institute of Cancer Research, London, UK., Keshishian H; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Ligon KL; Department of Oncologic Pathology, Dana Farber Cancer Institute, Boston, MA, 02215, USA., Carr SA; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Phoenix TN; Division of Pharmaceutical Sciences, James L. Winkle College of Pharmacy, University of Cincinnati, Cincinnati, OH, 45267, USA. phoenity@ucmail.uc.edu.; Research in Patient Services, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45267, USA. phoenity@ucmail.uc.edu., Bandopadhayay P; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA. Pratiti_bandopadhayay@dfci.harvard.edu.; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, 02215, USA. Pratiti_bandopadhayay@dfci.harvard.edu.; Department of Pediatrics, Harvard Medical School, Boston, MA, 02215, USA. Pratiti_bandopadhayay@dfci.harvard.edu.
Publikováno v:
Nature communications [Nat Commun] 2022 Feb 01; Vol. 13 (1), pp. 604. Date of Electronic Publication: 2022 Feb 01.