Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jerome Wilborn"'
Autor:
Robert M. Strieter, Jerome Wilborn, Marie D. Burdick, Steven L. Kunkel, Marc Peters-Golden, Leslie J. Crofford
Publikováno v:
Journal of Clinical Investigation. 95:1861-1868
Prostaglandin E2 (PGE2) inhibits fibroblast proliferation and collagen synthesis. In this study, we compared lung fibroblasts isolated from patients with idiopathic pulmonary fibrosis (F-IPF) and from patients undergoing resectional surgery for lung
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 268:L294-L301
Prostaglandin synthesis represents one means by which macrophages modulate inflammation. The initial enzyme in the metabolism of arachidonic acid to prostaglandins is cyclooxygenase (COX). Both constitutive (COX-1) and inducible (COX-2) isoforms are
Autor:
Jerome Wilborn, Marie D. Burdick, Marc B. Bailie, Robert M. Strieter, Marc Peters-Golden, Michael J. Coffey
Publikováno v:
The Journal of clinical investigation. 97(8)
Idiopathic pulmonary fibrosis (IPF) is a progressive disorder characterized by inflammation, fibroblast proliferation, and accumulation of extracellular matrix proteins. Leukotrienes (LTs) are pro-inflammatory and pro-fibrogenic mediators derived fro