Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jerome Roy Semakula"'
Autor:
Andrea L Jorgensen, Catherine Orrell, Catriona Waitt, Cheng-Hock Toh, Christine Sekaggya-Wiltshire, Dyfrig A Hughes, Elizabeth Allen, Emmy Okello, Gayle Tatz, Giovanna Culeddu, Innocent G Asiimwe, Jerome Roy Semakula, Johannes P Mouton, Karen Cohen, Marc Blockman, Mohammed Lamorde, Munir Pirmohamed
Publikováno v:
JMIR Research Protocols, Vol 12, p e46710 (2023)
BackgroundThe quality of warfarin anticoagulation among Sub-Saharan African patients is suboptimal. This is due to several factors, including a lack of standardized dosing algorithms, difficulty in providing timely international normalized ratio (INR
Externí odkaz:
https://doaj.org/article/8aa9d5caf1144261bbc13fcb1b01ef6e
Autor:
Pauline Byakika-Kibwika, Christine Sekaggya-Wiltshire, Jerome Roy Semakula, Jane Nakibuuka, Joseph Musaazi, James Kayima, Cornelius Sendagire, David Meya, Bruce Kirenga, Sarah Nanzigu, Arthur Kwizera, Fred Nakwagala, Ivan Kisuule, Misaki Wayengera, Henry G. Mwebesa, Moses R. Kamya, William Bazeyo
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background Several repurposed drugs such as hydroxychloroquine (HCQ) have been investigated for treatment of COVID-19, but none was confirmed to be efficacious. While in vitro studies have demonstrated antiviral properties of HCQ, data from
Externí odkaz:
https://doaj.org/article/998396d7775341c2858f30f8d62468b8
Autor:
Jerome Roy Semakula, Johannes P Mouton, Andrea Jorgensen, Claire Hutchinson, Shaazia Allie, Lynn Semakula, Neil French, Mohammed Lamorde, Cheng-Hock Toh, Marc Blockman, Christine Sekaggya-Wiltshire, Catriona Waitt, Munir Pirmohamed, Karen Cohen
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0227458 (2020)
INTRODUCTION:Warfarin is the most commonly prescribed oral anticoagulant in sub-Saharan Africa and requires ongoing monitoring. The burden of both infectious diseases and non-communicable diseases is high and medicines used to treat comorbidities may
Externí odkaz:
https://doaj.org/article/d501d1f8c9fe4eb6b772a772396b4760
Autor:
Jonathan Walubembe, Mike Engola Aremo, Conrad Tumwine, Florence Nabaale, Andrew Twinomasiko, Isaac Tukesiga, Phillip Ssenyomo, Apollo Mugaiga, Jerome Roy Semakula, Derrick Amone Olwedo, David Lagoro Kitara
Publikováno v:
The Pan African Medical Journal, Vol 33, Iss 161 (2019)
We present a histologically proven mucinous adenocarcinoma of the colon in a 40 year old female from Gulu, Northern Uganda. Her elder sister died at 25 years with advanced adenocarcinoma of colon similarly with her mother who died of the same illness
Externí odkaz:
https://doaj.org/article/3741da81021b4178bc3a4b0f89288867
Autor:
Andrea Jorgensen, Catherine Orrell, Catriona Waitt, Cheng-Hock Toh, Christine Sekaggya, Dyfrig Hughes, Elizabeth Allen, Emmy Okello, Gayle Tatz, Giovanna Celuddu, Innocent G Asiimwe, Jerome Roy Semakula, Johannes P Mouton, Karen Cohen, Marc Blockman, Mohammed Lamorde, Munir Pirmohamed
BACKGROUND The quality of warfarin anticoagulation among sub-Saharan African patients is sub-optimal. This is due to several factors including lack of standardized dosing algorithms; difficulty in providing timely INR results; lack of patient feedbac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::684c2af048698ed5e45e09845dcc0d96
https://doi.org/10.2196/preprints.46710
https://doi.org/10.2196/preprints.46710
Autor:
Munir Pirmohamed, Karen Cohen, Johannes P. Mouton, Catriona Waitt, Christine Sekaggya-Wiltshire, Marc Blockman, Jerome Roy Semakula
Publikováno v:
British Journal of Clinical Pharmacology
Patients in sub‐Saharan Africa generally have poor anticoagulation control. We review the potential reasons for this poor control, as well as the potential solutions. Challenges include the affordability and centralisation of anticoagulation care,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbcf4cdf3de7b4236315bdc81cc7e33e
https://doi.org/10.1111/bcp.14768
https://doi.org/10.1111/bcp.14768
Autor:
Andrea L. Jorgensen, Innocent G Asiimwe, Catriona Waitt, Karen Cohen, Eunice J. Zhang, Munir Pirmohamed, Johannes P. Mouton, Christine Sekaggya-Wiltshire, Marc Blockman, Emmy Okello, Claire Hutchinson, Jerome Roy Semakula, Mohammed Lamorde
Publikováno v:
CLINICAL PHARMACOLOGY & THERAPEUTICS
Warfarin remains the oral anticoagulant of choice in sub-Saharan Africa. However, dosing is challenging due to a highly variable clinical response for a given dose. This study aimed to develop and validate a clinical warfarin dose-initiation model in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68fea90364bb0c43c732924db7eb8f25
https://doi.org/10.1002/cpt.2128
https://doi.org/10.1002/cpt.2128
Autor:
Arthur Kwizera, Jane Nakibuuka, Misaki Wayengera, Henry Mwebesa, Ivan Kisuule, Cornelius Sendagire, Christine Sekaggya-Wiltshire, Joseph Musaazi, Pauline Byakika-Kibwika, James Kayima, Jerome Roy Semakula, Bruce Kirenga, William Bazeyo, Sarah Nanzigu, Fred Nakwagala, David B. Meya, Moses R. Kamya
BackgroundSeveral repurposed drugs such as hydroxychloroquine (HCQ) have been investigated for treatment of COVID-19, but none was confirmed to be efficacious. While in vitro studies have demonstrated antiviral properties of HCQ, data from clinical t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ddcb5190045ab954f4aaa3928c0ed29
https://doi.org/10.21203/rs.3.rs-506195/v1
https://doi.org/10.21203/rs.3.rs-506195/v1
Autor:
Geraldine Kisa, Catriona Waitt, Christine Sekaggya-Wiltshire, Marc Blockman, Karen Cohen, Jerome Roy Semakula, Johannes P. Mouton, Munir Pirmohamed
Publikováno v:
British journal of clinical pharmacologyREFERENCES. 87(10)
Warfarin has existed for >7 decades and has been the anticoagulant of choice for many thromboembolic disorders. The recent introduction of direct-acting oral anticoagulants (DOACs) has, however, caused a shift in preference by healthcare professional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2163cf5cae42afb84ae1d2745fe09d88
https://pubmed.ncbi.nlm.nih.gov/33624331
https://pubmed.ncbi.nlm.nih.gov/33624331
Publikováno v:
Research and Reports in Tropical Medicine
Nodding syndrome is an enigmatic neuropsychiatric and epileptiform disorder associated with psychomotor, mental, and physical growth retardation. The disorder affects otherwise previously normal children aged 3-18 years, with a slight preponderance f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43c1e91c570af319c279769b6d378aeb
http://europepmc.org/articles/PMC6049047
http://europepmc.org/articles/PMC6049047