Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Jerome O Cantor"'
Publikováno v:
International Journal of COPD, Vol 2008, Iss Issue 3, Pp 477-481 (2008)
Tapan Bhavsar, Xing Jian Liu, Hardik Patel, Ralph Stephani, Jerome O CantorSt John’s University, School of Pharmacy and Allied Health Sciences, New York, USAAbstract: This study examined the role of endothelin-1 (ET-1) in recruiting inflammatory ce
Externí odkaz:
https://doaj.org/article/8567114452104242b3b4e76706777b79
Autor:
Jerome O. Cantor, Gerard M. Turino
Publikováno v:
Chest. 155:266-271
Developing an effective treatment for COPD, and especially pulmonary emphysema, will require an understanding of how fundamental changes at the molecular level affect the macroscopic structure of the lung. Currently, there is no accepted model that e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44064d996081ad27487983fa5d495cc1
https://doi.org/10.1016/j.chest.2018.07.030
https://doi.org/10.1016/j.chest.2018.07.030
Autor:
Sherif G. El Bayadi, Gerard M. Turino, C Strange, Randolph J. Lipchik, James M. Stocks, Michael Campos, Robert A. Sandhaus, Xingjian Liu, Shuren Ma, Megan S. Devine, Jerome O. Cantor
Publikováno v:
Respiratory medicine. 182
Introduction A previous 2-week clinical trial of aerosolized hyaluronan (HA) in COPD showed a rapid reduction in lung elastic fiber breakdown, as measured by sputum levels of the unique elastin crosslinks, desmosine and isodesmosine (DID). To further
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5457e5ee30bfb9e665d7bb721c595f8f
https://pubmed.ncbi.nlm.nih.gov/33906126
https://pubmed.ncbi.nlm.nih.gov/33906126
Publikováno v:
Chest. 153:792-798
Insights into the clinical course of COPD indicate the need for new therapies for this condition. The discovery of alpha-1 antitrypsin deficiency (AATD) led to the protease-antiprotease imbalance hypothesis, which was applied to COPD related to AATD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95e553299f2f8cee27a5c4350a1711c5
https://doi.org/10.1016/j.chest.2017.12.016
https://doi.org/10.1016/j.chest.2017.12.016
Publikováno v:
International Journal of Chronic Obstructive Pulmonary Disease
Jerome Cantor,1 Shuren Ma,2 Gerard Turino2 1Department of Pharmaceutical Sciences, St John’s University, 2Department of Medicine, St Luke’s MountSinai Hospital Center, NewYork, NY, USA Abstract: A novel therapy for COPD involving the use of aeros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b46a7a63df14f89b51f9ccb28f2911fd
https://doi.org/10.2147/copd.s142156
https://doi.org/10.2147/copd.s142156
Publikováno v:
C63. MECHANISTIC STUDIES IN COPD.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a101d9b706f995ee1cb926506da0d88b
https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7432
https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7432
Publikováno v:
Lung. 195:93-99
Desmosine and isodesmosine (DID) are unique elastin crosslinks that may serve as biomarkers for elastic fiber degradation in chronic obstructive pulmonary disease. Previously, our laboratory found that the ratio of free to peptide-bound DID in bronch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f3e585fa818f9e3ebb2edfbb1d6b2c3
https://doi.org/10.1007/s00408-016-9956-2
https://doi.org/10.1007/s00408-016-9956-2
Publikováno v:
Annals of the American Thoracic Society. 13:S336-S340
Biomarkers of pathogenesis in chronic obstructive pulmonary disease (COPD) can significantly accelerate drug development. In COPD related to alpha-1 antitrypsin deficiency, the role of neutrophil elastase and its inhibition by alpha-1 antitrypsin pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54a4f0115aae08a9f42cf2b46eee3356
https://doi.org/10.1513/annalsats.201509-574kv
https://doi.org/10.1513/annalsats.201509-574kv
