Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Jerome M. Seyer"'
Autor:
M. A. Cremer, Linda K. Myers, Andrew H. Kang, Laura D Carbone, Grant W. Somes, Juan Bustillo, Elaine Steere, Stanley B. Kaplan, Kristine M. Lohr, Gurjit Kaeley, Miguel González, Arnold E. Postlethwaite, Jacob A. Aelion, Jerome M. Seyer, Kevin McKown
Publikováno v:
Arthritis & Rheumatism. 42:1204-1208
Objective To investigate the efficacy of oral type II collagen (CII) in the treatment of rheumatoid arthritis (RA), when added to existing therapy. Methods Patients with active RA (n = 190) were randomized into a 6-month, double-blind, placebo-contro
Publikováno v:
Immunology. 90:161-164
DBA/1 mice were administered type II collagen (CII) or collagen peptides intranasally before systemic immunization to determine whether tolerance could be induced and autoimmune arthritis suppressed. Although prior experiments have demonstrated that
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 271:R101-R108
Interleukin-1 (IL-1) is hypothesized to be involved in physiological sleep regulation and in sleep responses occurring during infectious disease. If this hypothesis is correct, then inhibition of endogenous IL-1 should reduce both normal sleep and N-
Publikováno v:
NeuroReport. 7:642-646
The involvement of tumor necrosis factor (TNF) in sleep regulation was investigated by blocking TNF using a synthetic TNF receptor fragment (TNFRF) in rabbits. Intracerebroventricular injection of 50 micrograms TNFRF decreased spontaneous non-rapid-e
Publikováno v:
Virology. 208(1):408-413
Phosphorylation status of the Sendai virus P protein was examined during virus infection and compared with cell-free phosphorylation. P protein from Sendai virus-infected (VI) and P/C gene-transfected (PT) mammalian cells and from purified virions (P
Autor:
Andrew H. Kang, Linda K. Myers, Jerome M. Seyer, John M. Stuart, Kuniaki Terato, Steven W. Cooper
Publikováno v:
Clinical Immunology and Immunopathology. 75:33-38
The murine model of collagen-induced arthritis is characterized by the development of an immune response against joint cartilage. Arthritis can be significantly suppressed by the administration of type II collagen (CII) or one of the CNBr peptides, C
Publikováno v:
Proceedings of the National Academy of Sciences. 92:2229-2233
Epidermal growth factor (EGF) stimulates adenylyl cyclase in the heart via activation of the stimulatory GTP-binding protein Gs. Therefore, employing peptides corresponding to regions in the cytosolic domain of the EGF receptor, we have investigated
Autor:
Yoshifumi Ninomiya, Megumi Kagawa, Manabu Sugimoto, Jerome M. Seyer, Yumiko Kishiro, Ichiro Naito, Toshitaka Oohashi, Ken Ichi Iyama, Yoshikazu Sado
Publikováno v:
The Journal of Cell Biology
Genes for the human alpha 5(IV) and alpha 6(IV) collagen chains have a unique arrangement in that they are colocalized on chromosome Xq22 in a head-to-head fashion and appear to share a common bidirectional promoter. In addition we reported a novel o
Autor:
Rajendra Raghow, Jerome M. Seyer, C. P. Simkevich, Juan Armendáriz-Borunda, Andrew H. Kang, N. Roy
Publikováno v:
Biochemical Journal. 304:817-824
Activation of liver Ito cells is characterized by increased proliferation, fibrogenesis, loss of cellular retinoid and change of cell-shape. Here, we have described fundamental differences between freshly isolated Ito cells (FIC) and long-term cultur
Autor:
Jerome M. Seyer, James F. Hainfeld, Mona T. Norcum, David M. Tillman, Deborah A. Wilkinson, Gerald M. Carlson, Tony N. Marion
Publikováno v:
Journal of Molecular Biology. 235:974-982
An epitope of the alpha-subunit of phosphorylase kinase from fast-twitch skeletal muscle was localized to the tips of the bilobal kinase molecule by two types of immunoelectron microscopy. This is the first direct evidence identifying the location of