Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Jerome Lowenstein"'
Publikováno v:
Toxins, Vol 16, Iss 5, p 227 (2024)
Uremia, also known as uremic syndrome, refers to the clinical symptoms in the final stage of renal failure. The definition of the term has changed over time due to an improved comprehension of the kidney’s function and the advancement of dialysis t
Externí odkaz:
https://doaj.org/article/dedb038766d841f68b339e6705d6593c
Autor:
Jerome Lowenstein, Sanjay K. Nigam
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Many putative uremic toxins—like indoxyl sulfate, p-cresol sulfate, kynurenic acid, uric acid, and CMPF—are organic anions. Both inter-organ and inter-organismal communication are involved. For example, the gut microbiome is the main source of in
Externí odkaz:
https://doaj.org/article/72612db021a24d16aec64bab278ea0ac
Autor:
Bjorn Meijers, Jerome Lowenstein
Publikováno v:
Toxins, Vol 14, Iss 4, p 274 (2022)
Indoxyl sulfate, closely related to indigo, a dye valued for it binding to cloth, has been recognized as a protein-bound solute bound to albumin, present in increased concentration in the serum of patients with impaired glomerular filtration (13). Th
Externí odkaz:
https://doaj.org/article/37f8d346c9954e65a15302f034b689be
Publikováno v:
Toxins, Vol 14, Iss 3, p 210 (2022)
Sodium–glucose cotransporter (SGLT) inhibitors are a class of oral hypoglycemic agents, which, in recent years, have been shown to improve renal and cardiovascular outcomes in patients with diabetic and non-diabetic chronic kidney disease. There re
Externí odkaz:
https://doaj.org/article/612b3789eafc41a59436f112665ec0c8
Autor:
Rohit Kumar, Avinash Adiga, Joshua Novack, Alex Etinger, Lawrence Chinitz, James Slater, Henriette deLoor, Bjorn Meijers, Robert S. Holzman, Jerome Lowenstein
Publikováno v:
Physiological Reports, Vol 8, Iss 4, Pp n/a-n/a (2020)
Abstract Measurement of the concentration of hippurate in the inferior vena cava and renal blood samples performed in 13 subjects with normal or near‐normal serum creatinine concentrations confirmed the prediction that endogenous hippurate was clea
Externí odkaz:
https://doaj.org/article/e63e2632af6b4768bb037e4a496de80a
Autor:
Aleksey Etinger, Sumit R Kumar, William Ackley, Leland Soiefer, Jonathan Chun, Prabjhot Singh, Eric Grossman, Albert Matalon, Robert S Holzman, Bjorn Meijers, Jerome Lowenstein
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192770 (2018)
BACKGROUND:There is growing evidence that the accumulation of protein- bound uremic retention solutes, such as indoxyl sulfate, p-cresyl sulfate and kynurenic acid, play a role in the accelerated cardiovascular disease seen in patients undergoing chr
Externí odkaz:
https://doaj.org/article/d74c7ffaa8b34685bb0efc34ca86418c
Autor:
Aleksey Etinger, Sumit R Kumar, William Ackley, Leland Soiefer, Jonathan Chun, Prabjhot Singh, Eric Grossman, Albert Matalon, Robert S Holzman, Bjorn Meijers, Jerome Lowenstein
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200980 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0192770.].
Externí odkaz:
https://doaj.org/article/ca9512d928bc481ca5ec2c9665845c7c
Autor:
Sachin Jhawar, Prabhjot Singh, Daniel Torres, Francisco Ramirez-Valle, Hania Kassem, Trina Banerjee, Igor Dolgalev, Adriana Heguy, Jiri Zavadil, Jerome Lowenstein
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118703 (2015)
Chronic renal failure is characterized by progressive renal scarring and accelerated arteriosclerotic cardiovascular disease despite what is considered to be adequate hemodialysis or peritoneal dialysis. In rodents with reduced renal mass, renal scar
Externí odkaz:
https://doaj.org/article/8887cc23a89149948fd31d4123f87ac0
Autor:
Lama Nazzal, Melody Ho, Nadim Zaidan, Menghan Liu, Zhan Gao, John R. Asplin, Robert Holzman, Ze Chen, Jerome Lowenstein, Chan Wang, Huilin Li, David S. Goldfarb, Martin J. Blaser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e60917c8301253d868f170d0ff21d69
https://doi.org/10.2139/ssrn.4382768
https://doi.org/10.2139/ssrn.4382768
Autor:
James Slater, Henriette de Loor, Björn Meijers, Joshua Novack, Jerome Lowenstein, Alex Etinger, Robert S. Holzman, Avinash Adiga, Rohit Kumar, Lawrence Chinitz
Publikováno v:
Physiological Reports
Physiological Reports, Vol 8, Iss 4, Pp n/a-n/a (2020)
Physiological Reports, Vol 8, Iss 4, Pp n/a-n/a (2020)
Measurement of the concentration of hippurate in the inferior vena cava and renal blood samples performed in 13 subjects with normal or near‐normal serum creatinine concentrations confirmed the prediction that endogenous hippurate was cleared on a