Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Jerome L. Moniot"'
Autor:
Joseph Wurdinger, Theodor Denzel, Janak Singh, Chris G. Papaioannou, Richard H. Mueller, Rita Fox, Rolf Herter, Peter Schierling, Thomas P. Kissick, Jerome L. Moniot, Christopher M. Cimarusti
Publikováno v:
Organic Process Research & Development. 6:863-868
An efficient synthesis of the monobactam aztreonam [[2S-[2α,3β(Z)]]-3[[(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-methyl-4-oxo-1-azetidinesulfonic acid] (1) by acylation of α-aminoazetidinone 22 with the regioselectively
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d886af18b59af7bb47f35d3554c9f40
https://doi.org/10.1021/op025572d
https://doi.org/10.1021/op025572d
Autor:
Jack Z. Gougoutas, John C. Harris, and Donald L. Wedding, David A. Thurston, Gus A. Kodersha, David A. Lust, William Early, Dennis Ronald D, Daniel H. Kim, Atul S. Kotnis, Dominique Thoraval, William J. Winter, James L. Berg, Merrill L. Davies, Peter J. Bernot, James H. Simpson, Jerome L. Moniot, Neal G. Anderson, Paul A. Jass, Douglas W. Phillipson, Kai Tse, Droghini Roberto, Andrew Nguyen, Thomas D. Ary, Lajeunesse Jean, John D. Dimarco, Venkatapuram A. Palaniswamy, Hoang D. Do, Gary D. Madding, Oscar W. Haas, Yeung Y. Chan, Polomski Robert E, Rajan P. Deshpande, Chien-Kuang Chen, John A. Grosso, Sandeep P. Modi
Publikováno v:
Organic Process Research & Development. 1:300-310
5-Fluoro-3-[3-[4-(5-methoxy-4-pyrimidinyl)-1-piperazinyl]propyl]-1H-indole dihydrochloride (1) facilitates 5-HT neurotransmission and was an antidepressant drug candidate. The development of a safe, rugged process for the large-scale, chromatography-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e6663a3ce15b3152d0cb3b0548517d9
https://doi.org/10.1021/op970213h
https://doi.org/10.1021/op970213h
Autor:
Barbara M. Ciaramella, David A. Lust, and Robert E. Polomski, Alan F Feldman, Neal G. Anderson, Steven S. Y. Wang, Linda Moran, Jerome L. Moniot
Publikováno v:
Organic Process Research & Development. 1:211-216
A safe, rugged process for the manufacture of a Monopril intermediate using a trimethylsilyl-mediated Arbuzov reaction was developed. The problems encountered and overcome in iterations from pilot plant to manufacturing are described. The final proce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56326a78acef707fe6576cbae54c2465
https://doi.org/10.1021/op970202o
https://doi.org/10.1021/op970202o
Publikováno v:
The Journal of Organic Chemistry. 51:3140-3143
La (S)-hydroxymethyl-5 pyrrolidone-2 (preparee a partir de l'acide L-glutamique est condensee avec le benzaldehyde en perhydro phenyl-3 pyrrolo [1,2-c] oxazolone-5; apres alkylation par le bromo-3 cyclohexene puis reduction, on obtient le trans-cyclo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95334371ab37e3953b07a563fd4fdab6
https://doi.org/10.1021/jo00366a011
https://doi.org/10.1021/jo00366a011
Preparation of phosphinic acids: Michael additions of phosphonous acids/esters to conjugated systems
Publikováno v:
Tetrahedron Letters. 25:4741-4744
A very mild and facile method for the preparation of phosphinic acids via Michael addition of phosphonous acids as well as esters, through an intermediate silyl alkyl phosphonite, to activated conjugated systems is described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abeb9fb1b3d22d93a03c7253adfd9d56
https://doi.org/10.1016/s0040-4039(01)81507-0
https://doi.org/10.1016/s0040-4039(01)81507-0
Publikováno v:
Tetrahedron Letters. 19:4617-4620
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb08b3935e00c043ca161ed26e13a15f
https://doi.org/10.1016/s0040-4039(01)85686-0
https://doi.org/10.1016/s0040-4039(01)85686-0
Autor:
Mary F. Malley, Jack Z. Gougoutas, Thomas P. Kissick, O. Kocy, Jerome L. Moniot, Fox Rita T, Janak Singh, Michael Wong
Publikováno v:
The Journal of Organic Chemistry. 53:205-208
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9261e469b9bd0707537db8c2b5807da
https://doi.org/10.1021/jo00236a046
https://doi.org/10.1021/jo00236a046
Publikováno v:
Tetrahedron Letters. 25:4737-4740
A very mild and simple method for the preparation of phosphinic acids from phosphonous acids through the intermediacy of silylalkyl phosphonites is described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9762e0b76690e218c76be820aae4b11
https://doi.org/10.1016/s0040-4039(01)81506-9
https://doi.org/10.1016/s0040-4039(01)81506-9
Publikováno v:
The Journal of Organic Chemistry. 44:4343-4346
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76da3c91828760ae02d6335868ed7364
https://doi.org/10.1021/jo01338a021
https://doi.org/10.1021/jo01338a021