Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Jerome C. Nwachukwu"'
Autor:
William H. Hudson, Ian Mitchelle S. de Vera, Jerome C. Nwachukwu, Emily R. Weikum, Austin G. Herbst, Qin Yang, David L. Bain, Kendall W. Nettles, Douglas J. Kojetin, Eric A. Ortlund
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Glucocorticoid receptor (GR) regulates immunity and inflammation but the mechanisms by which GR represses proinflammatory genes are still being debated. Here the authors use a multidisciplinary approach and show that GR binds to a cryptic site within
Externí odkaz:
https://doaj.org/article/4e26ab6d87a84291886bf3c3f88bfcfb
Autor:
Susan K. Logan, Michael J. Garabedian, William L. Gerald, Myles Brown, Samir S. Taneja, S. Joseph Huang, Qianben Wang, Susan Ha, Rachel Ruoff, Paolo Mita, Jerome C. Nwachukwu
The androgen receptor (AR) directs diverse biological processes through interaction with coregulators such as AR trapped clone-27 (ART-27). Our results show that ART-27 is recruited to AR-binding sites by chromatin immunoprecipitation analysis. In ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc9db14f25f3740a287b2963e3fe9252
https://doi.org/10.1158/0008-5472.c.6499736.v1
https://doi.org/10.1158/0008-5472.c.6499736.v1
Autor:
Herbert H. Samuels, Kathleen W. Kinnally, Sonia Martinez-Caballero, Anthony I. Vulin, Dangsheng Li, Jerome C. Nwachukwu, Sharmistha Das
We previously reported that amino acids 20 to 50 of nuclear receptor interacting factor-3 mediates rapid apoptosis in breast cancer cell lines but not in cells derived from other tissues. We refer to this short region as death domain-1 (DD1). Small i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7765752130fde6e12388b34c4988de35
https://doi.org/10.1158/0008-5472.c.6496497.v1
https://doi.org/10.1158/0008-5472.c.6496497.v1
Autor:
Susan K. Logan, Michael J. Garabedian, William L. Gerald, Myles Brown, Samir S. Taneja, S. Joseph Huang, Qianben Wang, Susan Ha, Rachel Ruoff, Paolo Mita, Jerome C. Nwachukwu
Supplementary Figure 1 from Genome-Wide Impact of Androgen Receptor Trapped clone-27 Loss on Androgen-Regulated Transcription in Prostate Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f5a0211bf1e72bc5caa74446d6d01fd
https://doi.org/10.1158/0008-5472.22381034
https://doi.org/10.1158/0008-5472.22381034
Autor:
Susan K. Logan, Michael J. Garabedian, William L. Gerald, Myles Brown, Samir S. Taneja, S. Joseph Huang, Qianben Wang, Susan Ha, Rachel Ruoff, Paolo Mita, Jerome C. Nwachukwu
Supplementary Table 1B from Genome-Wide Impact of Androgen Receptor Trapped clone-27 Loss on Androgen-Regulated Transcription in Prostate Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56748bfd5b7417c247ab8ee5de35d5c7
https://doi.org/10.1158/0008-5472.22381019
https://doi.org/10.1158/0008-5472.22381019
Autor:
Susan K. Logan, Michael J. Garabedian, William L. Gerald, Myles Brown, Samir S. Taneja, S. Joseph Huang, Qianben Wang, Susan Ha, Rachel Ruoff, Paolo Mita, Jerome C. Nwachukwu
Supplementary Figure 2 from Genome-Wide Impact of Androgen Receptor Trapped clone-27 Loss on Androgen-Regulated Transcription in Prostate Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1df5527703b7cea58070fbdc79eea41d
https://doi.org/10.1158/0008-5472.22381031.v1
https://doi.org/10.1158/0008-5472.22381031.v1
Autor:
Susan K. Logan, Michael J. Garabedian, William L. Gerald, Myles Brown, Samir S. Taneja, S. Joseph Huang, Qianben Wang, Susan Ha, Rachel Ruoff, Paolo Mita, Jerome C. Nwachukwu
Supplementary Figure 3 from Genome-Wide Impact of Androgen Receptor Trapped clone-27 Loss on Androgen-Regulated Transcription in Prostate Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa25fd9e554d2af540a2ebfd6f5cb9f6
https://doi.org/10.1158/0008-5472.22381028.v1
https://doi.org/10.1158/0008-5472.22381028.v1
Autor:
Susan K. Logan, Michael J. Garabedian, William L. Gerald, Myles Brown, Samir S. Taneja, S. Joseph Huang, Qianben Wang, Susan Ha, Rachel Ruoff, Paolo Mita, Jerome C. Nwachukwu
Supplementary Figure and Table Legends from Genome-Wide Impact of Androgen Receptor Trapped clone-27 Loss on Androgen-Regulated Transcription in Prostate Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::560b2cc54c7af8a73e9a28b08485b891
https://doi.org/10.1158/0008-5472.22381025.v1
https://doi.org/10.1158/0008-5472.22381025.v1
Autor:
Herbert H. Samuels, Kathleen W. Kinnally, Sonia Martinez-Caballero, Anthony I. Vulin, Dangsheng Li, Jerome C. Nwachukwu, Sharmistha Das
Supplementary Movie 1 from The Nuclear Receptor Interacting Factor-3 Transcriptional Coregulator Mediates Rapid Apoptosis in Breast Cancer Cells through Direct and Bystander-Mediated Events
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00db696571c27ee3d118d2e01d4a7116
https://doi.org/10.1158/0008-5472.22370700.v1
https://doi.org/10.1158/0008-5472.22370700.v1
Autor:
Sean W Fanning, Rinath Jeselsohn, Venkatasubramanian Dharmarajan, Christopher G Mayne, Mostafa Karimi, Gilles Buchwalter, René Houtman, Weiyi Toy, Colin E Fowler, Ross Han, Muriel Lainé, Kathryn E Carlson, Teresa A Martin, Jason Nowak, Jerome C Nwachukwu, David J Hosfield, Sarat Chandarlapaty, Emad Tajkhorshid, Kendall W Nettles, Patrick R Griffin, Yang Shen, John A Katzenellenbogen, Myles Brown, Geoffrey L Greene
Publikováno v:
eLife, Vol 7 (2018)
Acquired resistance to endocrine therapy remains a significant clinical burden for breast cancer patients. Somatic mutations in the ESR1 (estrogen receptor alpha (ERα)) gene ligand-binding domain (LBD) represent a recognized mechanism of acquired re
Externí odkaz:
https://doaj.org/article/582b84ec644248bbb6fb9af5a9be5532