Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jerome Busserolles"'
Autor:
George Shapovalov, Dimitra Gkika, Maily Devilliers, Artem Kondratskyi, Dmitri Gordienko, Jerome Busserolles, Alexandre Bokhobza, Alain Eschalier, Roman Skryma, Natalia Prevarskaya
Publikováno v:
Cell Reports, Vol 4, Iss 3, Pp 504-515 (2013)
Stimulation of μ-opioid receptors (OPRMs) brings powerful pain relief, but it also leads to the development of tolerance and addiction. Ensuing withdrawal in abstinent patients manifests itself with severe symptoms, including cold hyperalgesia, ofte
Externí odkaz:
https://doaj.org/article/8a36bed6f4564b81a08c9c9cfd1dd452
Autor:
Mélissa Delanne-Cuménal, Sylvain Lamoine, Mathieu Meleine, Youssef Aissouni, Laetitia Prival, Mathilde Fereyrolles, Julie Barbier, Christine Cercy, Ludivine Boudieu, Julien Schopp, Michel Lazdunski, Alain Eschalier, Stéphane Lolignier, Jérôme Busserolles
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 176, Iss , Pp 116887- (2024)
Background: The metastasis of tumors into bone tissue typically leads to intractable pain that is both very disabling and particularly difficult to manage. We investigated here whether riluzole could have beneficial effects for the treatment of prost
Externí odkaz:
https://doaj.org/article/fba694993c0445fda652c636373e8655
Autor:
David Balayssac, Jérôme Busserolles, Catherine Broto, Cristelle Dalbos, Laetitia Prival, Sylvain Lamoine, Damien Richard, Mercedes Quintana, Aurélia Herbet, Sandrine Hilairet, Yang Hu, Irena Loryan, Warren E. Glaab, Laura Micheli, Carla Ghelardini, Lorenzo Di Cesare Mannelli, Olivier Perrault, Mohamed Slaoui
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 167, Iss , Pp 115535- (2023)
Identifying compounds that are neurotoxic either toward the central or the peripheral nervous systems (CNS or PNS) would greatly benefit early stages of drug development by derisking liabilities and selecting safe compounds. Unfortunately, so far ass
Externí odkaz:
https://doaj.org/article/efd0b2fddcb7403794d7295e4d4dd042
Autor:
David Balayssac, Julie Durif, Céline Lambert, Cristelle Dalbos, Eric Chapuy, Monique Etienne, Claire Demiot, Jérôme Busserolles, Vincent Martin, Vincent Sapin
Publikováno v:
Toxics, Vol 11, Iss 12, p 1004 (2023)
Blood biomarkers, including neurofilament light chain (NfL), have garnered attention as potential indicators for chemotherapy-induced peripheral neuropathy (CIPN), a dose-limiting adverse effect of neurotoxic anticancer drugs. However, no blood bioma
Externí odkaz:
https://doaj.org/article/28b835c8e1d84e2888d8a6ec346ad5c3
Autor:
Marie Selvy, Catherine Mattévi, Cristelle Dalbos, Youssef Aissouni, Eric Chapuy, Pierre-Yves Martin, Aurore Collin, Damien Richard, Charles Dumontet, Jérôme Busserolles, Sakahlé Condé, David Balayssac
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 149, Iss , Pp 112915- (2022)
Background: Donepezil, a cholinesterase inhibitor approved in Alzheimer’s disease, has demonstrated analgesic and preventive effects in animal models of oxaliplatin-induced neuropathy. To improve the clinical interest of donepezil for the managemen
Externí odkaz:
https://doaj.org/article/4a3c89020b1444e2ae268de916d99bee
Autor:
Nicolas Kerckhove, Marie Selvy, Céline Lambert, Coralie Gonneau, Gabrielle Feydel, Caroline Pétorin, Agnès Vimal-Baguet, Sergey Melnikov, Sharif Kullab, Mohamed Hebbar, Olivier Bouché, Florian Slimano, Vincent Bourgeois, Valérie Lebrun-Ly, Frédéric Thuillier, Thibault Mazard, David Tavan, Kheir Eddine Benmammar, Brigitte Monange, Mohamed Ramdani, Denis Péré-Vergé, Floriane Huet-Penz, Ahmed Bedjaoui, Florent Genty, Cécile Leyronnas, Jérôme Busserolles, Sophie Trévis, Vincent Pinon, Denis Pezet, David Balayssac
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Oxaliplatin, a pivotal drug in the management of colorectal cancer, causes chemotherapy-induced peripheral neuropathy (CIPN) in a third of cancer survivors. Based on a previous cross-sectional study assessing oxaliplatin-related sensory CIPN in color
Externí odkaz:
https://doaj.org/article/2b597ee8a3434985a82d29f25ae2a813
Autor:
Marie Selvy, Nicolas Kerckhove, Bruno Pereira, Fantine Barreau, Daniel Nguyen, Jérôme Busserolles, Fabrice Giraudet, Aurélie Cabrespine, Carine Chaleteix, Martin Soubrier, Jacques-Olivier Bay, Richard Lemal, David Balayssac
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Bortezomib is a pivotal drug for the management of multiple myeloma. However, bortezomib is a neurotoxic anticancer drug responsible for chemotherapy-induced peripheral neuropathy (CIPN). CIPN is associated with psychological distress and a decrease
Externí odkaz:
https://doaj.org/article/c75b1e63fec145cca6c61e7e53c3319c
Autor:
David Balayssac, Bruno Pereira, Nicolas Kerckhove, Jérome Busserolles, Trevor Stanbury, Valérie Plence, Franck Bonnetain, Ivan Krakowski, Alain Eschalier
Publikováno v:
BMJ Open, Vol 9, Iss 6 (2019)
IntroductionMost patients (>70%) experience acute neuropathic symptoms shortly after oxaliplatin infusions. These symptoms are not always resolved between infusions. Overall, 30%–50% of patients suffer from chronic oxaliplatin-induced peripheral ne
Externí odkaz:
https://doaj.org/article/6f10730f80144045960004d0e6509bbf
Autor:
Stéphane Lolignier, Caroline Bonnet, Christelle Gaudioso, Jacques Noël, Jérôme Ruel, Muriel Amsalem, Jérémy Ferrier, Lise Rodat-Despoix, Valentine Bouvier, Youssef Aissouni, Laetitia Prival, Eric Chapuy, Françoise Padilla, Alain Eschalier, Patrick Delmas, Jérôme Busserolles
Publikováno v:
Cell Reports, Vol 11, Iss 7, Pp 1067-1078 (2015)
Cold-triggered pain is essential to avoid prolonged exposure to harmfully low temperatures. However, the molecular basis of noxious cold sensing in mammals is still not completely understood. Here, we show that the voltage-gated Nav1.9 sodium channel
Externí odkaz:
https://doaj.org/article/b41660b502d941c294543319bb5331b1
Autor:
Stéphane Lolignier, Muriel Amsalem, François Maingret, Françoise Padilla, Mélanie Gabriac, Eric Chapuy, Alain Eschalier, Patrick Delmas, Jérôme Busserolles
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23083 (2011)
Inflammation is known to be responsible for the sensitization of peripheral sensory neurons, leading to spontaneous pain and invalidating pain hypersensitivity. Given its role in regulating neuronal excitability, the voltage-gated Nav1.9 channel is a
Externí odkaz:
https://doaj.org/article/fdd502ad8c7744639fcd1d797028d43d