Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jerome Bressi"'
Autor:
Eric Sung, Jason ORourke, Raedun Clarke, Thomas H. Lee, Isabelle Riviere, Bi-Huei Yang, Rebecca Magdaleno, Gloria Hsia, Dell Farnan, Sjoukje J. C. van der Stegen, Stephanie Moreno, Chia-Wei Chang, Brigitte Senechal, Xu Yuan, Alma Gutierrez, Mark Plavsic, Meghan Eberhart, Bahram Valamehr, Abubakar Jalloh, Xiuyan Wang, Helena Shaked, Jerome Bressi, Yi-Shin Lai, Betsy Rezner, Devanjan S. Sikder, Ramzey Abujarour
Publikováno v:
Blood. 138:1766-1766
FT819 is a first-of-kind, allogeneic, off-the-shelf CAR T-cell therapy derived from a clonal master induced pluripotent stem cell (iPSC) line precisely engineered to insert a novel 1XX anti-CD19 chimeric antigen receptor (CAR) under the regulation of
Autor:
Chia-Wei Chang, Svetlana Gaidarova, Natalie Marquez-Solorzano, Sajid Mahmood, Robert Blum, Yijia Pan, Raedun Clarke, Rina M Mbofung, Soheila Shirinbak, Christine Chen, Fernanda Rodrigues Cugola, Bi-Huei Yang, Kai W. Wucherpfennig, Janel Huffman, Andrew Burns, Lucas Ferrari de Andrade, Antonio Fernandez-Perez, John Goulding, Martin Hosking, Karina Palomares, Mochtar Pribadi, Lauren Fong, Brian Groff, Thomas Dailey, Tom Lee, Ramzey Abujarour, Wen-I Yeh, Joy Grant, Moyar Ge, Samvel Nazaretyan, Miguel Meza, Jason O’Rouke, Paul Rogers, Nicholas Brookhouser, Bryan Hancock, Pei-Fang Tsai, Riya Kanherkar, Hui-yi Chu, Bahram Valamehr, Ryan Bjordahl, Jerome Bressi, Shohreh Sikaroodi, Aidan Keefe
Publikováno v:
Journal for ImmunoTherapy of Cancer. 9:A126-A126
BackgroundChimeric antigen receptor (CAR)-T cell therapy has revolutionized cancer treatment, but it is associated with significant dose-limiting toxicities, restricted tumor targeting (limited by specific antigen expression), and, notably, a lack of