Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jerome Boisbouvier"'
Autor:
Faustine Henot, Elisa Rioual, Adrien Favier, Pavel Macek, Elodie Crublet, Pierre Josso, Bernhard Brutscher, Matthias Frech, Pierre Gans, Claire Loison, Jerome Boisbouvier
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
To refold client proteins, HSP90 chaperone undergoes large structural rearrangements. Here the authors use NMR and molecular simulation and reveal structure and dynamics of a key functionally relevant metastable state of human HSP90α N-terminal doma
Externí odkaz:
https://doaj.org/article/a0e415192adb4a8f825b0f4fa98dd24f
Autor:
Ricarda Törner, Tatsiana Kupreichyk, Lothar Gremer, Elisa Colas Debled, Daphna Fenel, Sarah Schemmert, Pierre Gans, Dieter Willbold, Guy Schoehn, Wolfgang Hoyer, Jerome Boisbouvier
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Integrated kinetic and structural investigations reveal that the ubiquitous co-chaperonin prefoldin interacts with its coiled-coil helices on the islet amyloid polypeptide fibril surface and fibril ends to inhibit fibril elongation and secondary nucl
Externí odkaz:
https://doaj.org/article/4aaef45c98db4785a8b8bb52bd795ee5
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
The oligomerization of monomeric proteins into large, elongated, β-sheet-rich fibril structures (amyloid), which results in toxicity to impacted cells, is highly correlated to increased age. The concomitant decrease of the quality control system, co
Externí odkaz:
https://doaj.org/article/bf8d803a13c14d1698ee1ba3aa2ee670
Autor:
Diego F. Gauto, Leandro F. Estrozi, Charles D. Schwieters, Gregory Effantin, Pavel Macek, Remy Sounier, Astrid C. Sivertsen, Elena Schmidt, Rime Kerfah, Guillaume Mas, Jacques-Philippe Colletier, Peter Güntert, Adrien Favier, Guy Schoehn, Paul Schanda, Jerome Boisbouvier
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
NMR structure determination is challenging for proteins with a molecular weight above 30 kDa and atomic-resolution structure determination from cryo-EM data is currently not the rule. Here the authors describe an integrated structure determination ap
Externí odkaz:
https://doaj.org/article/b46e113a51c845d98317d17073be2ebe
Autor:
Barbara Zambelli, Priyanka Basak, Heidi Hu, Mario Piccioli, Francesco Musiani, Valquiria Broll, Lionel Imbert, Jerome Boisbouvier, Michael J Maroney, Stefano Ciurli
Publikováno v:
Metallomics
Metallomics, 2023, 15 (3), ⟨10.1093/mtomcs/mfad003⟩
Metallomics, 2023, 15 (3), ⟨10.1093/mtomcs/mfad003⟩
The maturation pathway for the nickel-dependent enzyme urease utilizes the protein UreE as a metallochaperone to supply Ni(II) ions. In Helicobacter pylori urease maturation also requires HypA and HypB, accessory proteins that are commonly associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27cd2b6e5ed1d1760ddf69f20a666865
https://doi.org/10.1093/mtomcs/mfad003
https://doi.org/10.1093/mtomcs/mfad003
Autor:
Lionel, Imbert, Rachel, Lenoir-Capello, Elodie, Crublet, Alicia, Vallet, Rida, Awad, Isabel, Ayala, Celine, Juillan-Binard, Hubert, Mayerhofer, Rime, Kerfah, Pierre, Gans, Emeric, Miclet, Jerome, Boisbouvier
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2199
The cell-free synthesis is an efficient strategy to produce in large scale protein samples for structural investigations. In vitro synthesis allows for significant reduction of production time, simplification of purification steps and enables product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::37d531a56a1554e295f105a8add5ac08
https://pubmed.ncbi.nlm.nih.gov/33125648
https://pubmed.ncbi.nlm.nih.gov/33125648
Autor:
Diego F, Gauto, Pavel, Macek, Alessandro, Barducci, Hugo, Fraga, Audrey, Hessel, Tsutomu, Terauchi, David, Gajan, Yohei, Miyanoiri, Jerome, Boisbouvier, Roman, Lichtenecker, Masatsune, Kainosho, Paul, Schanda
Publikováno v:
J Am Chem Soc
Aromatic residues are located at structurally important sites of many proteins. Probing their interactions and dynamics can provide important functional insight but is challenging in large proteins. Here, we introduce approaches to characterize dynam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8a1e6b7f001d24c67df9e4061194bcdd
https://pubmed.ncbi.nlm.nih.gov/31199882
https://pubmed.ncbi.nlm.nih.gov/31199882
Publikováno v:
Journal of biomolecular NMR. 27(2)
Rotational diffusion properties have been derived for the DNA dodecamer d(CGCGAATTCGCG)(2) from (13)C R(1rho) and R(1) measurements on the C(1'), C(3'), and C(4') carbons in samples uniformly enriched in (13)C. The narrow range of C-H bond vector ori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::82bd7872dfdc17dc43d75a1dcc094621
https://pubmed.ncbi.nlm.nih.gov/12913409
https://pubmed.ncbi.nlm.nih.gov/12913409