Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jerome Becot"'
Publikováno v:
Bioinformatics. 33:3658-3660
Motivation Identification of small molecules that could be interesting starting points for drug discovery or to investigate a biological system as in chemical biology endeavours is both time consuming and costly. In silico approaches that assist the
Autor:
Pierre Tufféry, Olivier Sperandio, Maria A. Miteva, Jerome Becot, Marek Vavrusa, Julien Rey, Bruno O. Villoutreix, David Lagorce, Céline M. Labbé
Publikováno v:
Nucleic Acids Research
Open screening endeavors play and will play a key role to facilitate the identification of new bioactive compounds in order to foster innovation and to improve the effectiveness of chemical biology and drug discovery processes. In this line, we devel
Autor:
Jerome Becot, Nicolas Bosc, Adrien H. Cerdan, Mélaine A. Kuenemann, Marek Vavrusa, Olivier Sperandio
Publikováno v:
Journal of chemical information and modeling. 57(10)
Given the difficulties to identify chemical probes that can modulate protein–protein interactions (PPIs), actors in the field have started to agree on the necessity to use PPI-tailored screening chemical collections. However, which type of scaffold