Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jerome Audoux"'
Autor:
Florence Rufflé, Jerome Audoux, Anthony Boureux, Sacha Beaumeunier, Jean-Baptiste Gaillard, Elias Bou Samra, Andre Megarbane, Bruno Cassinat, Christine Chomienne, Ronnie Alves, Sebastien Riquier, Nicolas Gilbert, Jean-Marc Lemaitre, Delphine Bacq-Daian, Anne Laure Bougé, Nicolas Philippe, Therese Commes
Publikováno v:
F1000Research, Vol 6 (2017)
Background: High-throughput next generation sequencing (NGS) technologies enable the detection of biomarkers used for tumor classification, disease monitoring and cancer therapy. Whole-transcriptome analysis using RNA-seq is important, not only as a
Externí odkaz:
https://doaj.org/article/6830ab11a0e74f8ea902dcb6f6467b31
Autor:
Kevin Yauy, François Lecoquierre, Stéphanie Baert-Desurmont, Detlef Trost, Aicha Boughalem, Armelle Luscan, Jean-Marc Costa, Vanna Geromel, Laure Raymond, Pascale Richard, Sophie Coutant, Mélanie Broutin, Raphael Lanos, Quentin Fort, Stenzel Cackowski, Quentin Testard, Abdoulaye Diallo, Nicolas Soirat, Jean-Marc Holder, Nicolas Duforet-Frebourg, Anne-Laure Bouge, Sacha Beaumeunier, Denis Bertrand, Jerome Audoux, David Genevieve, Laurent Mesnard, Gael Nicolas, Julien Thevenon, Nicolas Philippe
Publikováno v:
Genetics in Medicine. 24:1316-1327
Retrospective interpretation of sequenced data in light of the current literature is a major concern of the field. Such reinterpretation is manual and both human resources and variable operating procedures are the main bottlenecks.Genome Alert! metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b75e49ffcf32629d36974d0136e6d597
https://doi.org/10.1016/j.gim.2022.02.008
https://doi.org/10.1016/j.gim.2022.02.008
Autor:
Julien Thevenon, Kevin Yauy, Nicolas Duforet-Frebourg, Quentin Testard, Sacha Beaumeunier, Jerome Audoux, Benoit Simard, DImitri Larue, Michael Blum, VIrginie Bernard, David Geneviève, Denis Bertrand, Nicolas Philippe
Observing phenotyping practices from an international cohort of 1,686 cases revealed heterogeneity of phenotype reporting among clinicians. Heterogeneity limited their exploitation for diagnosis as only 43% of symptom-gene associations in the cohort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a22ed594c89e1a46ac9e01dfc7b612d7
https://doi.org/10.21203/rs.3.rs-2152267/v1
https://doi.org/10.21203/rs.3.rs-2152267/v1
Publikováno v:
Journal of Heterocyclic Chemistry. 43:1497-1503
Using a regioselective metallation in connection with Stille cross-coupling reaction, we report here an original synthetic route to obtain in few steps various flat tetra- or pentaheterocyclic compounds which could be potential intercalating DNA agen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c1d41890e303e0fefba80aef1f3d576
https://doi.org/10.1002/jhet.5570430612
https://doi.org/10.1002/jhet.5570430612
Publikováno v:
ChemInform. 38
Using a regioselective metallation in connection with Stille cross-coupling reaction, we report here an original synthetic route to obtain in few steps various flat tetra- or pentaheterocyclic compounds which could be potential intercalating DNA agen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edd40f5cde1ceb878a1f3bf564469dd5
https://doi.org/10.1002/chin.200713164
https://doi.org/10.1002/chin.200713164
Publikováno v:
ChemInform. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9928ec1eee9f3a00b100e8039adeadd9
https://doi.org/10.1002/chin.200445177
https://doi.org/10.1002/chin.200445177
Autor:
Gérald Guillaumet, Bruno Lebret, Eric Pasquinet, Jerome Audoux, Didier Poullain, Franck Suzenet, Ethel Garnier
Publikováno v:
The Journal of organic chemistry. 69(23)
In this paper, N-arylations between two heteroaryl compounds were studied. Conditions were found to generate selectively either 3- or 5-heteroarylamino-1,2,4-triazines by investigating anionic processes (use of bases such as 2,2',6,6'-tetramethylpipe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7abc24e3a28e2f970f2e338ab047b7ed
https://pubmed.ncbi.nlm.nih.gov/15527255
https://pubmed.ncbi.nlm.nih.gov/15527255
Publikováno v:
ChemInform. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69750d111f06858e22e81c0c699eb2d2
https://doi.org/10.1002/chin.200440158
https://doi.org/10.1002/chin.200440158
Publikováno v:
ChemInform. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::612be087be1a1e3752f43280d27adb56
https://doi.org/10.1002/chin.200434171
https://doi.org/10.1002/chin.200434171
Autor:
Jérôme Audoux, Nicolas Philippe, Rayan Chikhi, Mikaël Salson, Mélina Gallopin, Marc Gabriel, Jérémy Le Coz, Emilie Drouineau, Thérèse Commes, Daniel Gautheret
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-15 (2017)
Abstract We introduce a k-mer-based computational protocol, DE-kupl, for capturing local RNA variation in a set of RNA-seq libraries, independently of a reference genome or transcriptome. DE-kupl extracts all k-mers with differential abundance direct
Externí odkaz:
https://doaj.org/article/a0fa2c7cae7041fdacc12c1b15ebcd61