Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Jerome, Schaack"'
Autor:
Derek Strassheim, Vijaya Karoor, Hala Nijmeh, Philip Weston, Martin Lapel, Jerome Schaack, Timothy Sullivan, Edward C. Dempsey, Kurt R. Stenmark, Evgenia Gerasimovskaya
Publikováno v:
Cells, Vol 9, Iss 2, p 416 (2020)
Angiogenic vasa vasorum (VV) expansion plays an essential role in the pathogenesis of hypoxia-induced pulmonary hypertension (PH), a cardiovascular disease. We previously showed that extracellular ATP released under hypoxic conditions is an autocrine
Externí odkaz:
https://doaj.org/article/abc704ecf8194e7ba7592da666e8312c
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 4, Pp 668-673 (2003)
Adipophilin (ADPH), a prominent protein component of lipid storage droplets (LSDs), is postulated to be necessary for the formation and cellular function of these structures. The presence of significant sequence similarities within an ∼100 amino ac
Externí odkaz:
https://doaj.org/article/733d79984185440fa5cf2eb11aa2a4fc
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 6, Pp 910-915 (2001)
3T3-L1 cells have been used as a model to study the differentiation and physiology of adipocytes. Exogenous expression of proteins in these cells offers the prospect of understanding the protein's function(s) in adipose tissue. Viral vectors, in part
Externí odkaz:
https://doaj.org/article/3fa5cf5827d446d3affa4722f33afc8a
Autor:
David J. Orlicky, Jerome Schaack
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 3, Pp 460-466 (2001)
3T3-L1 cells offer an excellent model system for studies of differentiation and biochemistry of fat cells. However, these cells are limited in their utility by the low efficiency with which DNA can be introduced by transfection. Gene delivery by vira
Externí odkaz:
https://doaj.org/article/5c6b6baab70a4afbbd009a34d11fd432
Autor:
Xiaoping Yang, Francisco G La Rosa, Elizabeth Erin Genova, Kendra Huber, Jerome Schaack, James Degregori, Natalie J Serkova, Yuan Li, Lih-Jen Su, Elizabeth Kessler, Thomas W Flaig
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74809 (2013)
The development of the Cre recombinase-controlled (Cre/LoxP) technique allows the manipulation of specific tumorigenic genes, temporarily and spatially. Our original intention of this study was to investigate the role of Kras and p53 in the developme
Externí odkaz:
https://doaj.org/article/bd468581c8724f83b549b912ddc5e754
Autor:
Evgenia V. Gerasimovskaya, Derek Strassheim, Martin Lapel, Hala Nijmeh, T. Sullivan, Philip Weston, Edward C. Dempsey, Jerome Schaack, Vijaya Karoor, Kurt R. Stenmark
Publikováno v:
Cells
Volume 9
Issue 2
Cells, Vol 9, Iss 2, p 416 (2020)
Volume 9
Issue 2
Cells, Vol 9, Iss 2, p 416 (2020)
Angiogenic vasa vasorum (VV) expansion plays an essential role in the pathogenesis of hypoxia-induced pulmonary hypertension (PH), a cardiovascular disease. We previously showed that extracellular ATP released under hypoxic conditions is an autocrine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33afabdd551a2ea4bc37b75e044f79a6
http://europepmc.org/articles/PMC7072142
http://europepmc.org/articles/PMC7072142
Publikováno v:
PLoS ONE, Vol 4, Iss 9, p e7095 (2009)
BACKGROUND:Mitochondrial oxidative stress is a contributing factor in the etiology of numerous neuronal disorders. However, the precise mechanism(s) by which mitochondrial reactive oxygen species (ROS) modify cellular targets to induce the death of n
Externí odkaz:
https://doaj.org/article/9f4f9692487149f996a89a6776e49962
Autor:
Liping Qiao, Jerome Schaack, Amanda Nguyen, William W. Hay, Jianhua Shao, Samuel Lee, Jean-Sebastien Wattez
Publikováno v:
Diabetes, vol 66, iss 5
Hypoadiponectinemia has been widely observed in patients with gestational diabetes mellitus (GDM). To investigate the causal role of hypoadiponectinemia in GDM, adiponectin gene knockout (Adipoq−/−) and wild-type (WT) mice were crossed to produce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13bd113455bdce4e65e7dc33e9e20719
https://doi.org/10.2337/db16-1096
https://doi.org/10.2337/db16-1096
Autor:
Jaime F. Modiano, Donald Bellgrau, Ron T. McElmurry, Colleen L. Forster, Beth A. Lindborg, Jerome Schaack, Edward A. Zamora, Timothy O'Brien, Mitzi Lewellen, Jakub Tolar
Publikováno v:
Cancer Immunology, Immunotherapy. 64:1449-1460
The potential of mesenchymal stromal cells (MSCs) to inhibit anti-tumor immunity is becoming increasingly well recognized, but the precise steps affected by these cells during the development of an anti-tumor immune response remain incompletely under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9283fa3f8862e607d401f0cd3934f75
https://doi.org/10.1007/s00262-015-1749-6
https://doi.org/10.1007/s00262-015-1749-6
Autor:
Bonggi Lee, Min Lu, Hyung sun Yoo, Robert H. Mak, Nai-Wen Chi, Jianhua Shao, Gen-Sheng Feng, Wai W. Cheung, Liping Qiao, Jerome Schaack, Jerrold M. Olefsky
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 306:E1144-E1154
Macrophage infiltration plays an important role in obesity-induced insulin resistance. CCAAT enhancer-binding protein-α (C/EBPα) is a transcription factor that is highly expressed in macrophages. To examine the roles of C/EBPα in regulating macrop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63ccf30299e83d4526877a208cee6726
https://doi.org/10.1152/ajpendo.00002.2014
https://doi.org/10.1152/ajpendo.00002.2014