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of 8
pro vyhledávání: '"Jerome, Harms"'
Autor:
Marina Durward, Girish Radhakrishnan, Jerome Harms, Claire Bareiss, Diogo Magnani, Gary A Splitter
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34925 (2012)
Brucellosis is a common zoonotic disease that remains endemic in many parts of the world. Dissecting the host immune response during this disease provides insight as to why brucellosis is often difficult to resolve. We used a Brucella epitope specifi
Externí odkaz:
https://doaj.org/article/2a596dd87c1b4ed084c88869d5d49405
Publikováno v:
Journal of visualized experiments : JoVE. (45)
Carboxyfluorescein diacetate succinimidyl ester (CFSE) can be used to easily and quickly label a cell population of interest for in vivo investigation. This labeling has classically been used to study proliferation and migration. In the method presen
Publikováno v:
Journal of Visualized Experiments.
Autor:
Mike Khan, Jerome Harms, Leah Armon, Linda Eskra, Cherisse Hall, Menachem Banai, Judith Smith, Gary Splitter
Publikováno v:
The Journal of Immunology. 194:202.3-202.3
With greater than 500,000 new infections per year, brucellosis is the most prevalent zoonosis worldwide. Brucella melitensis are intracellular bacteria that invade and replicate within macrophages and dendritic cells. The bacterial second messenger c
Autor:
Mike Khan, Diogo Magnani, Jerome Harms, Girish Radhakrishnan, Marina Durward, Yi-Ping Liu, Gary Splitter, Judith Smith
Publikováno v:
The Journal of Immunology. 190:186.5-186.5
Brucella melitensis is a facultative intracellular bacterium that invades and replicates within macrophages and dendritic cells. With greater than 500,000 new infections per year, brucellosis is the most prevalent zoonosis worldwide. Currently, a saf
Publikováno v:
The Journal of Immunology. 188:55.14-55.14
Brucella melitensis is a facultative intracellular bacterium that causes brucellosis, the most prevalent zoonosis worldwide. As no current vaccine is available, and current therapy suboptimal, a better understanding of how Brucella establishes an int
Publikováno v:
The Journal of Immunology. 184:94.17-94.17
Brucella spp are highly infective human intracellular pathogens that cause the most prevalent worldwide zoonotic disease, with over 500,000 human infections yearly. No human vaccine exists. Since killed and subunit vaccines present limited efficacy a
Publikováno v:
The Journal of Immunology. 184:40.24-40.24
In areas of endemic brucellosis, prevention of infection via vaccine would be far more cost-effective than the World Health Organization suggested regimen of antibiotics. As with other intracellular organisms, subunit or killed vaccines present very