Safety and efficacy of pioglitazone for the delay of cognitive impairment in people at risk of Alzheimer's disease (TOMMORROW): a prognostic biomarker study and a phase 3, randomised, double-blind, placebo-controlled trial

Autor: Carl Chiang, Jacquelynn Copeland, Vanessa Raymont, Peter Connelly, Reto Kressig, Guy G. Potter, Daniel K. Burns, Stephen Pearson, Manish Saxena, Ann M. Saunders, Debra Fleischman, DeRen Huang, Thomas Leyhe, Gabriel Leger, Gigi Lefebvre, Mardik Donikyan, Natalie Denburg, Alex Knopman, Nancy Voight, James Burke, Philip Moore, James R. Burke, Margaret Newson, Stephen Haneline, Adam J. Schwarz, George Demakis, Joseph Butchart, Robert Mitchell, Mark Leibowitz, Michael Woodward, Robert Alexander, Concetta Forchetti, Emiliangelo Ratti, Andreas U. Monsch, Lon S. Schneider, Aaron Ritter, Joscelyn Agron-Figueroa, Fraser Inglis, Craig Curtis, Judith Neugroschl, Geraint Price, Mark Brody, Clark Johnson, Clive Ballard, Stephen Thein, Meredith Culp, Kristine Yaffe, Ahad Sabet, Walter Braude, Gregory Kirk, David Krefetz, Rupert Noad, Omid Omidvar, John Sass, Brenda L. Plassman, James Bergthold, Arne Klostermann, Haydn Till, Aaron Ellenbogen, Patrick Harrigan, Heinz-Peter Herbst, Joseph Kass, Lorna Wallace, Jennifer Robinson, Elliot Henderson, Felicia Goldstein, Christopher McWilliam, R. Clarnette, Jerry Halsten, Dan Rujescu, Silvana Micallef, Nestor Galvez-Jimenez, Jeffrey Ross, Dag Aarsland, Hugh Miller, Theresa Campbell, Jingtao Wu, Allan Levey, Liebhild Stratmann, Rosalyn Lai, Agnes Flöel, Richard Shingleton, Steve Higham, Pierre N. Tariot, Esteban Olivera, Sandra Carusa, Amanda Olley, Ricky Mofsen, Kathryn Goozee, Kara Lyons, Richard J. Brown, Marwan N. Sabbagh, Virginia De Sanctis, Jerome Goldstein, Hamid R. Sohrabi, Lefkos T. Middleton, Eugen Schlegel, Donna Munic-Miller, Sylvia Robinson, David Watson, Oda Ackermann, Ralph Votolato, Peter Bailey, Paul Massman, Daniel Gruener, Robert Perneczky, Frederick Schaerf, Craig W. Ritchie, Scott Losk, Christina Zimmerman, Mario Parra, Jill Crusey, Edward Zamrini, Christine Belden, Thomas Arnold, Alexander White, Linda Rice, Elizabeth Coulthard, Jane Martin, Anne Koplin, Rebecca Evans, Janet O'Neil, Oliver Peters, Raj Shah, Marshall Nash, Ronald Bradley, Kathleen A. Welsh-Bohmer, Howard Hassman, Scott Barton, Robert Cohen, Robert Stephenson, Jacobo Mintzer, Michael W. Lutz, Wendy Bond, Rachelle S. Doody, Ronald Hofner, Laura Samson

Publikováno v: The Lancet Neurology. 20:537-547

Background: The identification of people at risk of cognitive impairment is essential for improving recruitment in secondary prevention trials of Alzheimer's disease. We aimed to test and qualify a biomarker risk assignment algorithm (BRAA) to identi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::257db405d4f97f3e8da4448459b3c956
https://doi.org/10.1016/s1474-4422(21)00043-0

Spontaneous coronary artery dissection

Autor: Selvanayagam Niranjan, Saheb Al-Daher, Jerome Goldstein, Alexander Dashwood

Publikováno v: Singapore medical journal. 58(2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a775c0ea888606c42b5175158bbabe1
https://pubmed.ncbi.nlm.nih.gov/28210745

Sumatriptan/naproxen sodium for the acute treatment of probable migraine without aura: A randomized study

Autor: Jane Saiers, Frederick J. Derosier, Stephen D. Silberstein, Jonathan White, Susan A. McDonald, Richard B. Lipton, Sheena K. Aurora, Jerome Goldstein, Shelly E. Lener, Michael C Runken

Publikováno v: Cephalalgia. 34:268-279

Objective Probable migraine is a common, disabling migraine subtype fulfilling all but one of the diagnostic criteria for migraine. This study was conducted to evaluate the efficacy and tolerability of sumatriptan/naproxen sodium for the acute treatm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ee5f169ad1c2e399b981b77fe88577e
https://doi.org/10.1177/0333102413508242

Safety and efficacy of peripheral nerve stimulation of the occipital nerves for the management of chronic migraine: Results from a randomized, multicenter, double-blinded, controlled study

Autor: Stephen D Silberstein, David W Dodick, Joel Saper, Billy Huh, Konstantin V Slavin, Ashwini Sharan, Ken Reed, Samer Narouze, Alon Mogilner, Jerome Goldstein, Terrence Trentman, Julien Vaisman, Joseph Ordia, Peter Weber, Timothy Deer, Robert Levy, Roni L Diaz, Stephanie N Washburn, Nagy Mekhail

Publikováno v: Cephalalgia. 32:1165-1179

Background: Chronic migraine (CM) is a debilitating neurological disorder with few treatment options. Peripheral nerve stimulation (PNS) of the occipital nerves is a potentially promising therapy for CM patients. Methods: In this randomized, controll

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ed776c84a6fd84ab30ac79497e683739
https://doi.org/10.1177/0333102412462642

Twelve-Month Tolerability and Efficacy Study of NP101, the Sumatriptan Iontophoretic Transdermal System

Autor: Stephen D. Silberstein, Richard P. Singer, Timothy R. Smith, Mark Pierce, Neil Pugach, Jerome Goldstein

Publikováno v: Headache: The Journal of Head and Face Pain. 52:612-624

Objective.— To assess the long-term tolerability and efficacy of NP101, a novel transdermal sumatriptan patch being developed for the acute treatment of migraine. Background.— Nausea (with or without vomiting) and gastroparesis have been characte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b026c9052acd2ec81844183602fc4980
https://doi.org/10.1111/j.1526-4610.2012.02094.x