Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Jeroen Verhoeven"'
Autor:
Sarah Piron, Jeroen Verhoeven, Jan Courtyn, Ken Kersemans, Benedicte Descamps, Leen Pieters, Anne Vral, Christian Vanhove, Filip De Vos
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract A wide variety of 18F-labeled PSMA-targeting PET radiotracers have been developed, including [18F]AlF-PSMA-11. As there is only limited data on the comparison with other 18F-labeled PSMA PET tracers, a comparative preclinical study between [
Externí odkaz:
https://doaj.org/article/60dbea091fa540a9b74d62f8413038ea
Impact of the molar activity and PSMA expression level on [18F]AlF-PSMA-11 uptake in prostate cancer
Autor:
Sarah Piron, Jeroen Verhoeven, Emma De Coster, Benedicte Descamps, Ken Kersemans, Leen Pieters, Anne Vral, Christian Vanhove, Filip De Vos
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract This two-part preclinical study aims to evaluate prostate specific membrane antigen (PSMA) as a valuable target for expression-based imaging applications and to determine changes in target binding in function of varying apparent molar activi
Externí odkaz:
https://doaj.org/article/e86245019d2c44038a8b1e90bc80cbd1
Autor:
Glenn Pauwelyn, Lise Vlerick, Robrecht Dockx, Jeroen Verhoeven, Andre Dobbeleir, Tim Bosmans, Kathelijne Peremans, Christian Vanhove, Ingeborgh Polis, Filip De Vos
Publikováno v:
BMC Veterinary Research, Vol 15, Iss 1, Pp 1-11 (2019)
Abstract Background Currently, [18F] altanserin is the most frequently used PET-radioligand for serotonin2A (5-HT2A) receptor imaging in the human brain but has never been validated in dogs. In vivo imaging of this receptor in the canine brain could
Externí odkaz:
https://doaj.org/article/6b3ee56da56f4b00980243c550bbd958
Autor:
Jeroen Verhoeven, Julie Bolcaen, Valerie De Meulenaere, Ken Kersemans, Benedicte Descamps, Sam Donche, Caroline Van den Broecke, Tom Boterberg, Jean-Pierre Kalala, Karel Deblaere, Christian Vanhove, Filip De Vos, Ingeborg Goethals
Publikováno v:
Radiation Oncology, Vol 14, Iss 1, Pp 1-11 (2019)
Abstract Background Glioblastoma (GB) is the most common primary malignant brain tumor. Standard medical treatment consists of a maximal safe surgical resection, subsequently radiation therapy (RT) and chemotherapy with temozolomide (TMZ). An accurat
Externí odkaz:
https://doaj.org/article/bb749da0579d4f8192dd7ee9a9aa7cde
Autor:
Charlotte Bouckaert, Emma Christiaen, Jeroen Verhoeven, Benedicte Descamps, Valerie De Meulenaere, Paul Boon, Evelien Carrette, Kristl Vonck, Christian Vanhove, Robrecht Raedt
Publikováno v:
Diagnostics, Vol 11, Iss 8, p 1311 (2021)
Magnetic resonance imaging (MRI) is frequently used for preclinical treatment monitoring in glioblastoma (GB). Discriminating between tumors and tumor-associated changes is challenging on in vivo MRI. In this study, we compared in vivo MRI scans with
Externí odkaz:
https://doaj.org/article/24b258a77633411ab9463362dc721f34
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Background and Purpose: Glioblastomas are the most aggressive of all gliomas. The prognosis of these gliomas, which are classified as grade IV tumors by the World Health Organization (WHO), is poor. Combination therapy, including surgery, radiotherap
Externí odkaz:
https://doaj.org/article/1635a127d5ff49aaacf26b7a90c0f2ac
Autor:
Glenn Pauwelyn, Lise Vlerick, Robrecht Dockx, Jeroen Verhoeven, Andre Dobbeleir, Kathelijne Peremans, Ingeborg Goethals, Tim Bosmans, Christian Vanhove, Filip De Vos, Ingeborgh Polis
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218237 (2019)
Numerous studies have shown that the serotonin1A (5-HT1A) receptor is implicated in the pathophysiology and treatment of several psychiatric and neurological disorders. Furthermore, functional imaging studies in a variety of species have demonstrated
Externí odkaz:
https://doaj.org/article/e7d4e26465c7459a93a282ec8749534b
Autor:
Valerie De Meulenaere, Ellen Bonte, Jeroen Verhoeven, Jean-Pierre Kalala Okito, Leen Pieters, Anne Vral, Olivier De Wever, Luc Leybaert, Ingeborg Goethals, Christian Vanhove, Benedicte Descamps, Karel Deblaere
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0224130 (2019)
PURPOSE:Even with an optimal treatment protocol, the median survival of glioblastoma (GB) patients is only 12-15 months. Hence, there is need for novel effective therapies that improve survival outcomes. Recent evidence suggests an important role for
Externí odkaz:
https://doaj.org/article/38a087f14e4e4377ab0cdae0fcf5152f
Autor:
Sam Donche, Jeroen Verhoeven, Benedicte Descamps, Julie Bolcaen, Karel Deblaere, Tom Boterberg, Caroline Van den Broecke, Christian Vanhove, Ingeborg Goethals
Publikováno v:
Frontiers in Medicine, Vol 6 (2019)
Glioblastoma is the most aggressive and malignant primary brain tumor in adults. Despite the current state-of-the-art treatment, which consists of maximal surgical resection followed by radiation therapy, concomitant, and adjuvant chemotherapy, progr
Externí odkaz:
https://doaj.org/article/ab72f42ef9564cdaa0d5c47f313a245e
Autor:
Charlotte Bouckaert, Charlotte Germonpré, Jeroen Verhoeven, Seon-Ah Chong, Lucas Jacquin, Georges Mairet-Coello, Véronique Marie André, Karine Leclercq, Christian Vanhove, Filip De Vos, Caroline Van den Broecke, Ingeborg Goethals, Benedicte Descamps, Sam Donche, Evelien Carrette, Wytse Wadman, Paul Boon, Kristl Vonck, Robrecht Raedt
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 19, p 6999 (2020)
Seizures are common in patients with high-grade gliomas (30–60%) and approximately 15–30% of glioblastoma (GB) patients develop drug-resistant epilepsy. Reliable animal models are needed to develop adequate treatments for glioma-related epilepsy.
Externí odkaz:
https://doaj.org/article/477dcffe04e7468e8c740ef11801806e