Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Jeroen S van Zon"'
Autor:
Guizela Huelsz-Prince, Rutger Nico Ulbe Kok, Yvonne Goos, Lotte Bruens, Xuan Zheng, Saskia Ellenbroek, Jacco Van Rheenen, Sander Tans, Jeroen S van Zon
Publikováno v:
eLife, Vol 11 (2022)
During renewal of the intestine, cells are continuously generated by proliferation. Proliferation and differentiation must be tightly balanced, as any bias toward proliferation results in uncontrolled exponential growth. Yet, the inherently stochasti
Externí odkaz:
https://doaj.org/article/585b9959996249058c8c4dae60548621
Autor:
Joleen JH Traets, Servaas N van der Burght, Suzanne Rademakers, Gert Jansen, Jeroen S van Zon
Publikováno v:
eLife, Vol 10 (2021)
Cell fate is maintained over long timescales, yet molecular fluctuations can lead to spontaneous loss of this differentiated state. Our simulations identified a possible mechanism that explains life-long maintenance of ASE neuron fate in Caenorhabdit
Externí odkaz:
https://doaj.org/article/5d75689c480545208e8b7a52030a3fb3
Autor:
Rutger N U Kok, Laetitia Hebert, Guizela Huelsz-Prince, Yvonne J Goos, Xuan Zheng, Katarzyna Bozek, Greg J Stephens, Sander J Tans, Jeroen S van Zon
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0240802 (2020)
Time-lapse microscopy is routinely used to follow cells within organoids, allowing direct study of division and differentiation patterns. There is an increasing interest in cell tracking in organoids, which makes it possible to study their growth and
Externí odkaz:
https://doaj.org/article/8ed989329cd1438d88015140c15e88ae
Autor:
Dimitris Katsanos, Sneha L Koneru, Lamia Mestek Boukhibar, Nicola Gritti, Ritobrata Ghose, Peter J Appleford, Maria Doitsidou, Alison Woollard, Jeroen S van Zon, Richard J Poole, Michalis Barkoulas
Publikováno v:
PLoS Biology, Vol 15, Iss 11, p e2002429 (2017)
Biological systems are subject to inherent stochasticity. Nevertheless, development is remarkably robust, ensuring the consistency of key phenotypic traits such as correct cell numbers in a certain tissue. It is currently unclear which genes modulate
Externí odkaz:
https://doaj.org/article/6277508cb47d427395d2628aabc8f068
Publikováno v:
Molecular Systems Biology, Vol 5, Iss 1, Pp 1-12 (2009)
Abstract Phagocytosis is the process by which cells internalize particulate material, and is of central importance to immunity, homeostasis and development. Here, we study the internalization of immunoglobulin G‐coated particles in cells transfecte
Externí odkaz:
https://doaj.org/article/80372237a9a8478e92b23ed38f0c780a
Autor:
Philippe Nghe, Sarah Boulineau, Sebastian Gude, Pierre Recouvreux, Jeroen S van Zon, Sander J Tans
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75537 (2013)
The ability to spatially confine living cells or small organisms while dynamically controlling their aqueous environment is important for a host of microscopy applications. Here, we show how polyacrylamide layers can be patterned to construct simple
Externí odkaz:
https://doaj.org/article/b01735605ede47e58dacc1e10a2d0fc5
Autor:
Guizela Huelsz-Prince, Rutger Nico Ulbe Kok, Yvonne Goos, Lotte Bruens, Xuan Zheng, Saskia Ellenbroek, Jacco Van Rheenen, Sander Tans, Jeroen S van Zon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b442c54a005d8795d7cb94268c46c639
https://doi.org/10.7554/elife.80682.sa2
https://doi.org/10.7554/elife.80682.sa2
Autor:
Xuan Zheng, Max A. Betjes, Yvonne J. Goos, Guizela Huelsz-Prince, Hans Clevers, Jeroen S. van Zon, Sander J. Tans
Elucidating the dynamics of cellular differentiation in space and time is key to advancing organoid biology and technology. Direct visualization of differentiation patterns is challenging, however, in part because of the difficulty of simultaneously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb9b19824341a3a2635b03f309e7dcad
https://doi.org/10.1101/2022.06.27.497728
https://doi.org/10.1101/2022.06.27.497728
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(26)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c38fb2241fd9c506a09838d8b5055559
https://pubmed.ncbi.nlm.nih.gov/35733269
https://pubmed.ncbi.nlm.nih.gov/35733269
Self-renewing tissues require that a constant number of proliferating cells is maintained over time. This maintenance can be ensured at the single-cell level or the population level. Maintenance at the population level leads to fluctuations in the nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e125609ebef180fc950a066b27fbaa1
https://doi.org/10.1101/2022.03.10.483777
https://doi.org/10.1101/2022.03.10.483777