Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Jeroen Poodt"'
1
Akademický článek
Single nucleotide polymorphism (SNP)-based loss of heterozygosity (LOH) testing by real time PCR in patients suspect of myeloproliferative disease.
Autor: Cornelis J J Huijsmans, Jeroen Poodt, Jan Damen, Johannes C van der Linden, Paul H M Savelkoul, Johannes F M Pruijt, Mirrian Hilbink, Mirjam H A Hermans
Publikováno v: PLoS ONE, Vol 7, Iss 7, p e38362 (2012)
During tumor development, loss of heterozygosity (LOH) often occurs. When LOH is preceded by an oncogene activating mutation, the mutant allele may be further potentiated if the wild-type allele is lost or inactivated. In myeloproliferative neoplasms
Externí odkaz: https://doaj.org/article/f6bd04fcddb546c6ae5676fa5dd5df14
Zobrazit plný text záznamu
2
Sensitive Detection and Quantification of the JAK2V617F Allele by Real-Time PCR
Autor: Paul H. M. Savelkoul, Cornelis J. J. Huijsmans, Mirjam H. A. Hermans, Jeroen Poodt
Publikováno v: The Journal of Molecular Diagnostics. 13:558-564
A single G-to-T missense mutation in the gene for the JAK2 tyrosine kinase, leading to a V617F amino acid substitution, is commonly found in several myeloproliferative neoplasms. Reliable quantification of this mutant allele is of increasing clinical
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::25addac48b51e872adf677c116fda969
https://doi.org/10.1016/j.jmoldx.2011.04.002
Zobrazit plný text záznamu
3
A sensitive and reliable semi-quantitative real-time PCR assay to detectJAK2 V617F in blood
Autor: Mirjam H. A. Hermans, Jeroen Poodt, Rob Fijnheer, I B B Walsh
Publikováno v: Hematological Oncology. 24:227-233
Diagnosis of the myeloproliferative disorders, polycythemia vera (PV), essential thrombocythemia (ET) and idiopathic myelofibrosis (IMF) is difficult due to lack of diagnostic markers. Recently, the acquisition of a mutation in the Janus kinase 2 (JA
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::448d3c3204eded3d47b46705d88599cc
https://doi.org/10.1002/hon.800
Zobrazit plný text záznamu
4
A Newly Identified Deletion of 970 bp at the α-Globin Locus That Removes the Promoter Region of the α1 Gene
Autor: Jeroen Poodt, Mirjam H. A. Hermans, Ita B.B. Walsh, Henk A.M. Martens, Bente Felix-Schollaart
Publikováno v: Hemoglobin. 30:471-477
The most common causes of alpha-thalassemia (thal) are deletions that remove a part, or one or both of the functional alpha-globin genes. These deletions cause diminished expression of the alpha-globin protein, which may result in relatively low hemo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::175b10f73e3fe8bd5ea4897670e255c9
https://doi.org/10.1080/03630260600868113
Zobrazit plný text záznamu
5
Allelic Imbalance at the HER2/TOP2A Locus in Breast Cancer
Autor: Cornelis J. J. Huijsmans, Mirjam H. A. Hermans, Johannes C van der Linden, Paul H. M. Savelkoul, Henny Rigter, Adriaan J. C. van den Brule, Jeroen Poodt, Mirrian Hilbink
Publikováno v: Diagnostic Pathology
Diagnostic Pathology, 10:56. BioMed Central
Huijsmans, C J J, van den Brule, A J C, Rigter, H, Poodt, J, van der Linden, J C, Savelkoul, P H M, Hilbink, M & Hermans, M H A 2015, ' Allelic imbalance at the HER2/TOP2A locus in breast cancer ', Diagnostic pathology, vol. 10, 56 . https://doi.org/10.1186/s13000-015-0289-x
Annals of Oncology, 24. Oxford University Press
Diagnostic pathology, 10:56. BioMed Central
Huijsmans, C J J, Rigter, H, van den Brule, A J, Poodt, J, van der Linden, J C, Savelkoul, P H M, Hilbink-Smolders, M & Hermans, M H A 2013, ' Allelic Imbalance at the HER2/TOP2A Locus in Breast Cancer ', Annals of Oncology, vol. 24, pp. iii29 . https://doi.org/10.1093/annonc/mdt084.14
Background Breast cancer is a heterogeneous disease with various histological features and molecular markers. These are utilized for the prediction of clinical outcome and therapeutic decision making. In addition to well established markers such as H
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed8ad57861d5ac4c0e4ac123f10607d6
https://doi.org/10.1093/annonc/mdt084.14
Zobrazit plný text záznamu
6
Sensitive detection and quantification of the JAK2V617F allele by real-time PCR blocking wild-type amplification by using a peptide nucleic acid oligonucleotide
Autor: Cornelis J J, Huijsmans, Jeroen, Poodt, Paul H M, Savelkoul, Mirjam H A, Hermans
Publikováno v: The Journal of molecular diagnostics : JMD. 13(5)
A single G-to-T missense mutation in the gene for the JAK2 tyrosine kinase, leading to a V617F amino acid substitution, is commonly found in several myeloproliferative neoplasms. Reliable quantification of this mutant allele is of increasing clinical
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c3dc96ab04d347584f5dd43fbfaa2ece
https://pubmed.ncbi.nlm.nih.gov/21723417
Zobrazit plný text záznamu
8
[Resistance to coumarin derivatives due to mutated vitamin-K enzyme]
Autor: Mirjam H A, Hermans, Jeroen, Poodt, J H H Anke, van Geest-Daalderop, Nathalie C, Péquériaux, Jean M H, Conemans
Publikováno v: Nederlands tijdschrift voor geneeskunde. 153
In 2006 a case report was published in this journal describing partial acenocoumarol- and phenprocoumon resistance in a 78-year-old man. A mutation in the VKORC1 gene was suggested to be the cause of the observed resistance. We examined the patient a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::285d6c958f8e9c914f1413213d6a06b5
https://pubmed.ncbi.nlm.nih.gov/19857286
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje