Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Jeroen J M A Hendrikx"'
Autor:
Daphne M V de Vries-Huizing, Michelle W J Versleijen, Michiel Sinaasappel, Iris Walraven, Martine M Geluk-Jonker, Margot E T Tesselaar, Jeroen J M A Hendrikx, Berlinda J de Wit-van der Veen, Marcel P M Stokkel
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0260073 (2021)
BackgroundMainly severe (CTCAE grade 3-4) haematotoxicity during peptide receptor radionuclide therapy (PRRT) is reported in literature due to major clinical impact, however moderate (CTCAE grade 2) haematotoxicity is common and could affect therapy
Externí odkaz:
https://doaj.org/article/49f0ebf26a2d4259ac04d82f4bf2bdd1
Autor:
Hinke Siebinga, Berlinda J. de Wit-van der Veen, Daphne M. V. de Vries-Huizing, Wouter V. Vogel, Jeroen J. M. A. Hendrikx, Alwin D. R. Huitema
Publikováno v:
EJNMMI Physics, Vol 11, Iss 1, Pp 1-24 (2024)
Abstract Background There is an unmet need for prediction of treatment outcome or patient selection for [177Lu]Lu-PSMA therapy in patients with metastatic castration-resistant prostate cancer (mCRPC). Quantification of the tumor exposure–response r
Externí odkaz:
https://doaj.org/article/8fff240eb4dd480799fca12f85a0fb21
Autor:
Elke A. van Brandwijk, Else A. Aalbersberg, Arman S. Hosseini, Alwin D. R. Huitema, Jeroen J. M. A. Hendrikx
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-12 (2024)
Abstract Background Steps have been taken by pharmaceutical companies to obtain marketing authorisation of PSMA ligands in the European Union. Since December 2022, Locametz® (PSMA-11, gozetotide) is licensed as kit for manual radiolabelling with gal
Externí odkaz:
https://doaj.org/article/d1af9e6243bf4d65b83e51713dbb1b7c
Autor:
Hinke Siebinga, Berlinda J. de Wit-van der Veen, Jos H. Beijnen, Marcel P. M. Stokkel, Thomas P. C. Dorlo, Alwin D. R. Huitema, Jeroen J. M. A. Hendrikx
Publikováno v:
EJNMMI Physics, Vol 10, Iss 1, Pp 1-18 (2023)
Abstract Background Prediction of [177Lu]Lu-HA-DOTATATE kidney and tumor uptake based on diagnostic [68Ga]Ga-HA-DOTATATE imaging would be a crucial step for precision dosing of [177Lu]Lu-HA-DOTATATE. In this study, the population pharmacokinetic (PK)
Externí odkaz:
https://doaj.org/article/7d39074066094585b56c1d2b07482192
Autor:
Hinke Siebinga, Bastiaan M. Privé, Steffie M. B. Peters, James Nagarajah, Thomas P. C. Dorlo, Alwin D. R. Huitema, Berlinda J. deWit‐van der Veen, Jeroen J. M. A. Hendrikx
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 8, Pp 1060-1071 (2023)
Abstract Studies to evaluate and optimize [177Lu]Lu‐PSMA treatment focus primarily on individual patient data. A population pharmacokinetic (PK) dosimetry model was developed to explore the potential of using imaging data as input for population PK
Externí odkaz:
https://doaj.org/article/8669aa79881c42eab0d580af6a0f9877
Autor:
Hinke Siebinga, Jeroen J. M. A. Hendrikx, Alwin D. R. Huitema, Berlinda J. de Wit-van der Veen
Publikováno v:
EJNMMI Research, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Background Folate intake might reduce [68Ga]Ga-PSMA-11 uptake in tissues due to a competitive binding to the PSMA receptor. For diagnostic imaging, this could impact decision making, while during radioligand therapy this could affect treatme
Externí odkaz:
https://doaj.org/article/3a9b811c4b1b4b72a3fe199276077d71
Autor:
Hinke Siebinga, Berlinda J. de Wit-van der Veen, Jos H. Beijnen, Thomas P. C. Dorlo, Alwin D. R. Huitema, Jeroen J. M. A. Hendrikx
Publikováno v:
EJNMMI Research, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Background Little is known about parameters that have a relevant impact on (dis)similarities in biodistribution between various 68Ga-labeled somatostatin analogues. Additionally, the effect of tumor burden on organ uptake remains unclear. Th
Externí odkaz:
https://doaj.org/article/76713150121a44bea16f200db7235fbf
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 7, Iss 1, Pp 1-10 (2022)
Abstract Background [177Lu]Lu-PSMA is used for the treatment of metastatic castration-resistant prostate cancer. For in-house productions, quality control methods are essential for ensuring product quality, and thus patient safety. During HPLC method
Externí odkaz:
https://doaj.org/article/fd3405ea37b84d6cba7021bd4f5ef4bc
Autor:
Else A. Aalbersberg, Lotte van Andel, Martine M. Geluk-Jonker, Jos H. Beijnen, Marcel P. M. Stokkel, Jeroen J. M. A. Hendrikx
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 5, Iss 1, Pp 1-11 (2020)
Abstract Background Lymph node dissection is a therapeutic option for prostate cancer patients with a high risk of- or proven lymph node metastases. Radioguided surgery after intravenous injection of [99mTc]Tc-PSMA could improve the selectivity of ly
Externí odkaz:
https://doaj.org/article/da61c274600b40ceaab947e2e1cf7302
Autor:
Chayenne H. A. M. Veerman, Hinke Siebinga, Daphne M. V. de Vries-Huizing, Margot E. T. Tesselaar, Jeroen J. M. A. Hendrikx, Marcel P. M. Stokkel, Else A. Aalbersberg
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 50:1434-1441