Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jeroen C.W. Rijk"'
Autor:
Michiel Alexander de Raaf, Marieke Meijer, Manon Beekhuijzen, Jeroen C.W. Rijk, Sylvia M.G.J. Pelgrom
Publikováno v:
Reproductive Toxicology. 88:56-66
Recently several OECD test guidelines were updated to include thyroid hormone measurements for assessing endocrine disruptor potency, which led to an imperative need to align interpretation of these results by the different stakeholders. We therefore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3667cea63818ad5487d106c99e8a9ad5
https://doi.org/10.1016/j.reprotox.2019.07.014
https://doi.org/10.1016/j.reprotox.2019.07.014
Autor:
Walter M.A. Westerink, Jeroen C.W. Rijk, Sylvia M.G.J. Pelgrom, Simon U. Jonis, Helma M. Barentsen, Jeannette J.C. Paulussen
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 106
From October 2016 the REACH Regulation requires an alternative testing strategy for skin sensitization. The current paper describes our experience when putting into practice the REACH alternative testing strategy with a modification for 50 industrial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7d8fee1937df33a45141240c22a8a51
https://pubmed.ncbi.nlm.nih.gov/31112721
https://pubmed.ncbi.nlm.nih.gov/31112721
Autor:
Saskia S. Sterk, Mario Thevis, Eva de Rijke, Leendert A. van Ginkel, Martien L. Essers, Toine F H Bovee, Jeroen C.W. Rijk
Publikováno v:
Food Additives & Contaminants. Pt. A, Chemistry, Analysis, Control, Exposure & Risk Assessment, 30(9), 1517-1526
Food Additives & Contaminants. Pt. A, Chemistry, Analysis, Control, Exposure & Risk Assessment 30 (2013) 9
Food Additives & Contaminants. Pt. A, Chemistry, Analysis, Control, Exposure & Risk Assessment 30 (2013) 9
For future targeted screening in National Residue Control Programmes, the metabolism of seven SARMs, from the arylpropionamide and the quinolinone classes, was studied in vitro using S9 bovine liver enzymes. Metabolites were detected and identified w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1231437f9e51f5522d93188fc37934c
https://doi.org/10.1080/19440049.2013.810346
https://doi.org/10.1080/19440049.2013.810346
Autor:
Jeroen C.W. Rijk, Marco Blokland, Toine F.H. Bovee, Ad A. C. M. Peijnenburg, Ron L.A.P. Hoogenboom, Arjen Lommen
Publikováno v:
Chemical Research in Toxicology 25 (2012) 8
Chemical Research in Toxicology, 25(8), 1720-1731
Chemical Research in Toxicology, 25(8), 1720-1731
The recently OECD validated H295R steroidogenesis assay provides an in vitro alternative to evaluate the potential interference of exogenous compounds with endogenous steroid hormone synthesis. Currently, this assay is used for a simple negative-posi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c5f91c152468f81a2adeac28bb9565c
https://doi.org/10.1021/tx3001779
https://doi.org/10.1021/tx3001779
Autor:
Toine F.H. Bovee, Jeroen C.W. Rijk, Carlos Van Peteghem, Michel W. F. Nielen, Ilse Becue, Christof Van Poucke
Publikováno v:
Analytical and Bioanalytical Chemistry 396 (2010) 2
Analytical and Bioanalytical Chemistry, 396(2), 799-808
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
Analytical and Bioanalytical Chemistry, 396(2), 799-808
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
DHEA (3 beta-hydroxy-androst-5-en-17-one) is a natural steroid prohormone. Despite a lack of information on the effect, DHEA and other prohormones are frequently used as a food supplement by body-builders. DHEA is suspected for growth promoting abuse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c1396c66ffe4099308efb91424d74c3
https://doi.org/10.1007/s00216-009-3265-z
https://doi.org/10.1007/s00216-009-3265-z
Autor:
Harrie Besselink, Si Wang, Jeroen C.W. Rijk, Toine F.H. Bovee, Ivonne M.C.M. Rietjens, René Houtman, Abraham Brouwer, Ad A. C. M. Peijnenburg
Publikováno v:
Toxicological sciences 141 (2014) 1
Toxicological sciences, 141(1), 78-89
Toxicological sciences, 141(1), 78-89
In the present study, a previously established integrated testing strategy (ITS) for in vitro estrogenicity testing was extended with additional in vitro assays in order to broaden its sensitivity to different modes of action resulting in apparent es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6f96259c5d9d1483239c503196cf87a
https://research.wur.nl/en/publications/extending-an-in-vitro-panel-for-estrogenicity-testing-the-added-v
https://research.wur.nl/en/publications/extending-an-in-vitro-panel-for-estrogenicity-testing-the-added-v
Autor:
Jeroen C.W. Rijk, Ron L.A.P. Hoogenboom, Peter J.M. Hendriksen, Marit Reitsma, Toine F.H. Bovee, Ad A. C. M. Peijnenburg
Publikováno v:
Toxicological sciences 132 (2013) 1
Toxicological sciences, 132(1), 64-74
Toxicological sciences, 132(1), 64-74
Photoinitiators used in food packaging ink, such as 2-isopropylthioxanthone (2-ITX), have been shown to migrate into food and beverages. Recently, several studies indicated that 2-ITX might be an endocrine disrupting chemical. In the present work, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e77bc0eea6a8d37759d1b7e6889ea19
https://research.wur.nl/en/publications/endocrine-disrupting-effects-of-thioxanthone-photoinitiators
https://research.wur.nl/en/publications/endocrine-disrupting-effects-of-thioxanthone-photoinitiators
Autor:
Martin van den Berg, Jeroen C.W. Rijk, Majorie B.M. van Duursen, Sandra M. Nijmeijer, Evelien E.J.W. Smeets
Publikováno v:
Toxicology and Applied Pharmacology, 269(2), 132-140
Toxicology and Applied Pharmacology 269 (2013) 2
Toxicology and Applied Pharmacology 269 (2013) 2
Breast cancer treatment by the aromatase inhibitor Letrozole (LET) or Selective Estrogen Receptor Modulator Tamoxifen (TAM) can result in the onset of menopausal symptoms. Women often try to relieve these symptoms by taking menopausal supplements con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a84071e2aa43555bd8182138d6254e00
https://research.wur.nl/en/publications/phytoestrogens-in-menopausal-supplements-induce-er-dependent-cell
https://research.wur.nl/en/publications/phytoestrogens-in-menopausal-supplements-induce-er-dependent-cell
Autor:
M.J. Groot, Jan S Ossenkoppele, Ad A. C. M. Peijnenburg, Peter J.M. Hendriksen, Ewa Szalowska, Geert Stoopen, Si Wang, Jeroen C.W. Rijk
Publikováno v:
Toxicology in Vitro, 27(5), 1513-1524
Toxicology in Vitro 27 (2013) 5
Toxicology in Vitro 27 (2013) 5
Precision cut liver slices (PCLSs) are widely used as a model to study hepatotoxicity. For culturing of PCLS diverse protocols are used which could affect slices viability and results. We aimed to identify the most optimal culture protocol for mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18f90df0746095dbd2d1fe2d50b06e2f
https://pubmed.ncbi.nlm.nih.gov/23531554
https://pubmed.ncbi.nlm.nih.gov/23531554
Autor:
Toine F.H. Bovee, Marieke J. Pen, Ad A. C. M. Peijnenburg, Ivonne M.C.M. Rietjens, Jeroen C.W. Rijk, Jac M.M.J.G. Aarts, Si Wang
Publikováno v:
Analytical Biochemistry, 435(1), 83-92
Analytical Biochemistry 435 (2013) 1
Analytical Biochemistry 435 (2013) 1
In the current study, a set of 12 reference compounds was tested in a low-density DNA microchip that contains probes for 11 different estrogen-responsive marker genes. Our results show that the seven most informative marker genes on the chip resulted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bfb3d433c48589b3aa4d0b63f6717b4
https://pubmed.ncbi.nlm.nih.gov/23296041
https://pubmed.ncbi.nlm.nih.gov/23296041