Zobrazeno 1 - 10 of 56 pro vyhledávání: '"Jeroen, van Bergen"'
1
Akademický článek
Multiantigen pan-sarbecovirus DNA vaccines generate protective T cell immune responses
Autor: Jeroen van Bergen, Marcel G.M. Camps, Iris N. Pardieck, Dominique Veerkamp, Wing Yan Leung, Anouk A. Leijs, Sebenzile K. Myeni, Marjolein Kikkert, Ramon Arens, Gerben C. Zondag, Ferry Ossendorp
Publikováno v: JCI Insight, Vol 8, Iss 21 (2023)
SARS-CoV-2 is the third zoonotic coronavirus to cause a major outbreak in humans in recent years, and many more SARS-like coronaviruses with pandemic potential are circulating in several animal species. Vaccines inducing T cell immunity against broad
Externí odkaz: https://doaj.org/article/aaf8e2ad065a44ffa855a479af325901
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2
Akademický článek
Potential impact of celiac disease genetic risk factors on T cell receptor signaling in gluten-specific CD4+ T cells
Autor: Olivier B. Bakker, Aarón D. Ramírez-Sánchez, Zuzanna A. Borek, Niek de Klein, Yang Li, Rutger Modderman, Yvonne Kooy-Winkelaar, Marie K. Johannesen, Filomena Matarese, Joost H. A. Martens, Vinod Kumar, Jeroen van Bergen, Shuo-Wang Qiao, Knut E. A. Lundin, Ludvig M. Sollid, Frits Koning, Cisca Wijmenga, Sebo Withoff, Iris H. Jonkers
Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Celiac disease is an auto-immune disease in which an immune response to dietary gluten leads to inflammation and subsequent atrophy of small intestinal villi, causing severe bowel discomfort and malabsorption of nutrients. The major instigat
Externí odkaz: https://doaj.org/article/66b9019aaac7432d846ad8c14c396c51
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3
Akademický článek
Dominant Antiviral CD8+ T Cell Responses Empower Prophylactic Antibody-Eliciting Vaccines Against Cytomegalovirus
Autor: Iris N. Pardieck, Suzanne van Duikeren, Dominique M. B. Veerkamp, Dena J. Brasem, Anke Redeker, Jeroen van Bergen, Wanda Han, Ferry Ossendorp, Gerben Zondag, Ramon Arens
Publikováno v: Frontiers in Immunology, Vol 13 (2022)
Human cytomegalovirus (HCMV) is an ubiquitous herpesvirus that can cause serious morbidity and mortality in immunocompromised or immune-immature individuals. A vaccine that induces immunity to CMV in these target populations is therefore highly neede
Externí odkaz: https://doaj.org/article/a5de808e927c4a01b312233c537f6907
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5
Akademický článek
A poly-neoantigen DNA vaccine synergizes with PD-1 blockade to induce T cell-mediated tumor control
Autor: Elena Tondini, Tsolere Arakelian, Koen Oosterhuis, Marcel Camps, Suzanne van Duikeren, Wanda Han, Ramon Arens, Gerben Zondag, Jeroen van Bergen, Ferry Ossendorp
Publikováno v: OncoImmunology, Vol 8, Iss 11 (2019)
The combination of immune-stimulating strategies has the potency to improve immunotherapy of cancer. Vaccination against neoepitopes derived from patient tumor material can generate tumor-specific T cell immunity, which could reinforce the efficacy o
Externí odkaz: https://doaj.org/article/a0f12396a0b84eb88bdbdd0e67d0bb3a
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6
Pyroptosis-inducing active caspase-1 as a genetic adjuvant in anti-cancer DNA vaccination
Autor: Tsolere Arakelian, Koen Oosterhuis, Elena Tondini, Mandy Los, Jana Vree, Mariska van Geldorp, Marcel Camps, Bram Teunisse, Iris Zoutendijk, Ramon Arens, Gerben Zondag, Ferry Ossendorp, Jeroen van Bergen
Publikováno v: Vaccine, 40(13), 2087-2098. ELSEVIER SCI LTD
Pyroptosis is a recently discovered form of inflammatory programmed necrosis characterized by caspase1-mediated and gasdermin D-dependent cell death leading to the release of pro-inflammatory cytokines such as Interleukin-1 beta (IL-18). Here, we eva
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec80e0de40e2dfde584f79dc55f58ceb
https://doi.org/10.1016/j.vaccine.2022.02.028
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7
770 Personalized synthetic polyepitope DNA cancer vaccines encoding a novel pyroptotic adjuvant to generate effective anti-tumor T cell immunity
Autor: Kedar Moharana, Ferry Ossendorp, Jeroen van Bergen, Iris Zoutendijk, Ramon Arens, Gerben Zondag, Tsolere Arakelian, Marcel Camps, Bram Teunisse
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundAs every tumor carries its unique set of neoantigens distinguishing it from healthy tissue, cancer vaccines need to be produced quickly and on an individual basis to swiftly induce a broad immune response targeting multiple antigens. DNA pr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da19f8acf19c184615e2fcdc25f1f27e
https://doaj.org/article/e46de3bc419b4f84a8147e35f5c19ba6
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8
Potential impact of celiac disease genetic risk factors on T cell receptor signaling in gluten-specific CD4+ T cells
Autor: Frits Koning, Yang Li, Joost H.A. Martens, Aarón D. Ramírez-Sánchez, Olivier B. Bakker, Vinod Kumar, Rutger Modderman, Zuzanna Borek, Marie K. Johannesen, Ludvig M. Sollid, Yvonne Kooy-Winkelaar, Filomena Matarese, Knut E.A. Lundin, Iris Jonkers, Niek de Klein, Shuo-Wang Qiao, Cisca Wijmenga, Jeroen van Bergen, Sebo Withoff
Publikováno v: Scientific Reports, 11, 1
Scientific Reports, 11(1):9252, 1-15. Nature Publishing Group
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports, 11(1). NATURE RESEARCH
Scientific Reports, 11
Celiac disease is an auto-immune disease in which an immune response to dietary gluten leads to inflammation and subsequent atrophy of small intestinal villi, causing severe bowel discomfort and malabsorption of nutrients. The major instigating facto
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5f64629d645aa8a255bdaa5b3903393
https://doi.org/10.1038/s41598-021-86612-5
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9
Dominant Antiviral CD8
Autor: Iris N, Pardieck, Suzanne, van Duikeren, Dominique M B, Veerkamp, Dena J, Brasem, Anke, Redeker, Jeroen, van Bergen, Wanda, Han, Ferry, Ossendorp, Gerben, Zondag, Ramon, Arens
Publikováno v: Frontiers in immunology. 13
Human cytomegalovirus (HCMV) is an ubiquitous herpesvirus that can cause serious morbidity and mortality in immunocompromised or immune-immature individuals. A vaccine that induces immunity to CMV in these target populations is therefore highly neede
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ab795f0dcf5dfd1776efc44ebf3fb5cb
https://pubmed.ncbi.nlm.nih.gov/35154089
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10
Mass cytometry reveals innate lymphoid cell differentiation pathways in the human fetal intestine
Autor: Jeroen van Bergen, Nicola Pezzotti, Allan Thompson, Elmar Eisemann, Boudewijn P. F. Lelieveldt, Frits Koning, Na Li, Vincent van Unen, Anna Vilanova, Thomas Höllt, Susana M. Chuva de Sousa Lopes
Publikováno v: Journal of Experimental Medicine
The Journal of Experimental Medicine
Journal of Experimental Medicine, 215(5), 1383-1396
The Journal of Experimental Medicine, 215(5)
Li et al. apply mass cytometry to delineate the fetal gut innate lymphoid cell (ILC) population and utilize a t-SNE–based approach to predict potential differentiation trajectories. They identify an int-ILC subset that differentiates into NK cells
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47e82eef8a98084a3aeaa6c31ed82252
https://doi.org/10.1084/jem.20171934
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