Zobrazeno 1 - 5 of 5 pro vyhledávání: '"Jerod Denton"'
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Akademický článek
Characterization of four structurally diverse inhibitors of SUR2-containing KATP channels
Autor: Kangjun Li, Vaishali Satpute Janve, Jerod Denton
Publikováno v: Channels, Vol 18, Iss 1 (2024)
Vascular smooth muscle ATP-sensitive potassium (KATP) channels play critical roles in modulating vascular tone and thus represent important drug targets for diverse cardiovascular pathologies. Despite extensive research efforts spanning several decad
Externí odkaz: https://doaj.org/article/e5a4d005f8a84498b4a79a932f8b0c3d
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4
A selective inhibitor of the sperm-specific potassium channel SLO3 impairs human sperm function
Autor: Maximilian Lyon, Ping Li, Juan J. Ferreira, Roman M. Lazarenko, Sujay V. Kharade, Meghan Kramer, Samantha J. McClenahan, Emily Days, Joshua A. Bauer, Brittany D. Spitznagel, C. David Weaver, Aluet Borrego Alvarez, Lis C. Puga Molina, Pascale Lybaert, Saayli Khambekar, Alicia Liu, Craig W. Lindsley, Jerod Denton, Celia M. Santi
Publikováno v: Proceedings of the National Academy of Sciences. 120
To fertilize an oocyte, the membrane potential of both mouse and human sperm must hyperpolarize (become more negative inside). Determining the molecular mechanisms underlying this hyperpolarization is vital for developing new contraceptive methods an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ede63a72f24deecc4d9bbc9e46c1f884
https://doi.org/10.1073/pnas.2212338120
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Plný text Recenzováno Digitální knihovna AV ČR
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