Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jerneja Opara"'
Publikováno v:
Drugs in R&D, Vol 23, Iss 3, Pp 211-220 (2023)
Abstract Background and Objectives Risk assessment related to bioequivalence study outcome is critical for effective planning from the early stage of drug product development. The objective of this research was to evaluate the associations between so
Externí odkaz:
https://doaj.org/article/b5bb7643332d44b7985aa5c0709f9467
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 48:241-255
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72f508a5dc1b24fdf9455439a812082c
https://doi.org/10.1007/s13318-023-00821-z
https://doi.org/10.1007/s13318-023-00821-z
Publikováno v:
Journal of Pharmaceutical Sciences. 110:3069-3081
The physiological properties of the gastrointestinal tract, such as pH, fluid volume, bile salt concentration, and gastrointestinal transit time, are highly variable in vivo. These properties can affect the dissolution and absorption of a drug, depen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b2c80dab882b915e1be3f8af5bb65e6
https://doi.org/10.1016/j.xphs.2021.04.007
https://doi.org/10.1016/j.xphs.2021.04.007
Autor:
Rebeka Jereb, Dejan Krajcar, Helena Vrbanac, Jerneja Opara, Bostjan Petek, Sandra Berglez, Igor Legen, Jurij Trontelj
Publikováno v:
European journal of pharmaceutics and biopharmaceutics, str. 113-120 : Ilustr., Vol. 149, 2020
COBISS-ID: 13176839
COBISS-ID: 13176839
The highly variable physiological conditions within the gastrointestinal tract can cause variable drug release and absorption from the orally administrated dosage forms. The emptying of the gastric content is one of the most critical physiological pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b910fd4d96543e526f154b703806d03
https://plus.cobiss.net/cobiss/si/en/bib/4884849
https://plus.cobiss.net/cobiss/si/en/bib/4884849
Publikováno v:
AAPS PharmSciTech. 21(1)
A physiologically based pharmacokinetic (PBPK) absorption model was developed in GastroPlus™ based on data on intravenous, immediate-release (IR), and modified-release (MR) drug products. The predictability of the model was evaluated by comparing p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3dc2e96055010f9f62ff442f2e70b02
https://pubmed.ncbi.nlm.nih.gov/31820131
https://pubmed.ncbi.nlm.nih.gov/31820131
Akademický článek
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Autor:
Igor Legen, Jerneja Opara
Publikováno v:
The AAPS Journal. 16:324-334
The usefulness of neuro-fuzzy (NF) models as an alternative in vitro-in vivo relationship (IVIVR) tool and as a support to quality by design (QbD) in generic drug development is presented. For drugs with complicated pharmacokinetics, immediate releas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa0df2b04f2b53959d757721f3f4fd90
https://doi.org/10.1208/s12248-014-9569-8
https://doi.org/10.1208/s12248-014-9569-8
Autor:
Jerneja Opara, Janez Kerc
Publikováno v:
International Journal of Pharmaceutics. 335:106-113
A new peroral amoxicillin/clavulanate therapeutic system composed of immediate release tablet and controlled release floating capsule was developed and evaluated by in vivo bioavailability study. Pharmacokinetic (PK) parameters for amoxicillin and cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99fe7fa819b7d04c2e9a7c5d7da9fc6a
https://doi.org/10.1016/j.ijpharm.2006.11.007
https://doi.org/10.1016/j.ijpharm.2006.11.007