Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Jernej Wagger"'
Autor:
Luka Vah, Tadej Medved, Uroš Grošelj, Marina Klemenčič, Črtomir Podlipnik, Bogdan Štefane, Jernej Wagger, Marko Novinec, Jurij Svete
Publikováno v:
Molecules, Vol 27, Iss 15, p 4764 (2022)
In silico evaluation of various regioisomeric 5- and 3-hydroxy-substituted alkyl 1-aryl-1H-pyrazole-4-carboxylates and their acyclic precursors yielded promising results with respect to their binding in the active site of dihydroorotate dehydrogenase
Externí odkaz:
https://doaj.org/article/e280863337764378a368bf50affeebc2
Publikováno v:
ARKIVOC, Vol 2012, Iss 3, Pp 49-65 (2011)
Externí odkaz:
https://doaj.org/article/d7c297a7517645c48bd7b2e85cb03c0b
Autor:
Jurij Svete, Helena Brodnik Žugelj, Uroš Grošelj, Lara Lavrenčič, Andraž Oštrek, Jernej Wagger, Dejan Slapšak, Marko Novinec, Nika Strašek, Marina Klemenčič
Publikováno v:
Bioorganic Chemistry. 89:102982
The reactions between 5-substituted pyrazolidine-3-ones, aldehydes, and methyl methacrylate provided tetrahydropyrazolo[1,2-a]pyrazole-1-carboxylates as mixtures of syn- and anti-diastereomers. Testing for inhibition of dihydroorotate dehydrogenase o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::962e50e2350bd38fc65cba631832fde2
https://doi.org/10.1016/j.bioorg.2019.102982
https://doi.org/10.1016/j.bioorg.2019.102982
Autor:
Jernej Wagger, Eric E. Swayze, Michael E. Østergaard, Robert D. Giacometti, Bradley L. Merner, Punit P. Seth, Stephen Hanessian
Publikováno v:
The Journal of Organic Chemistry. 78:9064-9075
A constrained tricyclic analogue of α-L-LNA (2), which contains dual modes of conformational restriction about the ribose sugar moiety, has been synthesized and characterized by X-ray crystallography. Thermal denaturation experiments of oligonucleot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c2e168e7dcac6f0a4869cd03ea34f77
https://doi.org/10.1021/jo401170y
https://doi.org/10.1021/jo401170y
Autor:
Reiner Beckert, Jernej Wagger, Jurij Svete, Branko Stanovnik, Georg Dahmann, David Kralj, Friedrich Schiller
Publikováno v:
ARKIVOC, Vol 2012, Iss 3, Pp 49-65 (2011)
Treatment of β-keto ester 8 with hydrazines 9a-g gave 1'-substituted tert-butyl 2-(5-hydroxy-1H- pyrazol-3-yl)ethylcarbamates 10a-e and 2-(5-oxo-2,5-dihydro-1H-pyrazol-3-yl)ethylcarbamates 11f,g. Acidolytic deprotection of 10b,c afforded the corresp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7098ec765a62feeac20ba6a673d9ea0
https://doi.org/10.3998/ark.5550190.0013.305
https://doi.org/10.3998/ark.5550190.0013.305
Publikováno v:
Tetrahedron: Asymmetry. 22:1364-1371
The effect of substituents on the chiral solvating properties of 13 different (S)-1,6-dialkylpiperazine-2,5-diones (S)-1a–m and five (3S,6S)-1,3,6-trialkyl analogues (S,S)-1n–r was studied by NMR in CDCl3 with methyl (RS)-N-benzoylleucinate (RS)-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dad4c63cfa802b625ec2efd1ce40cea1
https://doi.org/10.1016/j.tetasy.2011.07.019
https://doi.org/10.1016/j.tetasy.2011.07.019
Autor:
Jurij Svete, Črt Malavašič, Amalija Golobič, Katarina Stare, Jure Bezenšek, Uroš Grošelj, Branko Stanovnik, Jernej Wagger
Publikováno v:
Tetrahedron: Asymmetry. 22:629-640
Eleven (S)-1,6-dialkylpiperazine-2,5-diones and five (3S,6S)-1,3,6-trialkylpiperazine-2,5-diones were prepared in three steps from the corresponding (S)-α-amino acid esters comprising of reductive N-alkylation, N-acylation and cyclisation. The synth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f4b01acb1a462c982d2fe5511d16151
https://doi.org/10.1016/j.tetasy.2011.03.014
https://doi.org/10.1016/j.tetasy.2011.03.014
Autor:
Tanja Kolesa, Anton Meden, Jurij Svete, Jernej Wagger, Branko Stanovnik, Uroš Grošelj, Katarina Stare, Jure Bezenšek
Publikováno v:
Tetrahedron Letters. 51:3392-3397
Microwave-assisted [2+2] cycloaddition of (E)-3-dimethylamino-1-heteroaryl-prop-2-en-1-ones to dimethyl acetylenedicarboxylates gives (2E,3E)-dimethyl-2-[(dimethylamino)methylene]-3-(substituted)succinates in 8–91% yield. In the case of a 4,5-dihyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3347044aa7b120e9bea90713b6ae261f
https://doi.org/10.1016/j.tetlet.2010.04.106
https://doi.org/10.1016/j.tetlet.2010.04.106
Publikováno v:
Synlett. 2010:1197-1200
Two N-benzylated analogues of the antioxidant, radical scavenging, and neuroprotective alkaloid neoechinulin A were prepared. Since, according to SAR studies, stereochemistry does not play an important role, both analogues were prepared in racemic fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e196e832a57107ad7bf3e748cc04291
https://doi.org/10.1055/s-0029-1219812
https://doi.org/10.1055/s-0029-1219812
Autor:
Jernej Wagger, David Kralj, Miha Friedrich, Anton Meden, Jurij Svete, Uroš Grošelj, Sonja Kiraly-Potpara, Georg Dahmann, Branko Stanovnik
Publikováno v:
Tetrahedron. 65:7151-7162
A seven-step synthesis of 1-substituted 5-(2-acylaminoethyl)-1H-pyrazole-4-carboxamides 20 as the pyrazole analogues of histamine was developed. The synthesis starts with a three-step preparation of N(1)-substituted methyl 5-(2-tert-butoxycarbonylami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d070cf6c8e0b0ae8d8479be270c5a99b
https://doi.org/10.1016/j.tet.2009.06.021
https://doi.org/10.1016/j.tet.2009.06.021