Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jermaine Khumalo"'
Publikováno v:
JCI Insight, Vol 5, Iss 20 (2020)
Impaired tolerance to innocuous particles during allergic asthma has been linked to increased plasticity of FoxP3+ regulatory T cells (Tregs) reprogramming into pathogenic effector cells, thus exacerbating airway disease. However, failure of toleranc
Externí odkaz:
https://doaj.org/article/61532bb05a0449818c421afe982cf861
Autor:
Jermaine Khumalo, Mark Nicol, Diana Hardie, Rudzani Muloiwa, Phindile Mteshana, Colleen Bamford
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173948 (2017)
INTRODUCTION:Accurate etiological diagnosis of meningitis is important, but difficult in resource-limited settings due to prior administration of antibiotics and lack of viral diagnostics. We aimed to develop and validate 2 real-time multiplex PCR (R
Externí odkaz:
https://doaj.org/article/bab0dab65b96490d9de23ff82509bffa
Publikováno v:
Onderstepoort Journal of Veterinary Research, Vol 81, Iss 1, Pp e1-e6 (2014)
With the extensive use of antibiotics in livestock production, surveillance revealed an increase in Salmonella resistance to the commonly used antimicrobials in veterinary and public health. This serious threat to health care is further exacerbated b
Externí odkaz:
https://doaj.org/article/cd1d29fc7f39442c9d4610e5677156c0
Autor:
Chia, Julius E, Faye, Martin, Jermaine, Khumalo, Tesfaye, Brook, Modjirom, Ndoutabe, Ahmed, Jamal, Anfumbom, Kfutwah
Publikováno v:
In The Lancet 26 October-1 November 2024 404(10463):1637-1637
Autor:
Sabelo Hadebe, Jermaine Khumalo, Martyna Scibiorek, Sandisiwe Mangali, Anca F. Savulescu, Amkele Ngomti, Frank Brombacher, Katelyn Jones, Javan Okendo, Nontobeko Mthembu
Allergic asthma is a disease driven by T helper 2 (Th2) cells, eosinophilia, airway hyperresponsiveness (AHR) and IgE-secreting B cells. Asthma is largely controlled by corticosteroids and β2 adregenic receptor agonists that target and relax airway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aeefd3130c1db1840e614bb1825d2a57
https://doi.org/10.21203/rs.3.rs-891683/v1
https://doi.org/10.21203/rs.3.rs-891683/v1
Publikováno v:
Allergy
Background Allergic asthma is a chronic inflammatory airway disease driven predominantly by a TH2 immune response to environmental allergens. IL‐4Rα‐signaling is essential for driving TH2‐type immunity to allergens. Anti‐TH2 therapies have t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8c9c193ed5de5d468ea74193dd0448a
https://doi.org/10.1111/all.14137
https://doi.org/10.1111/all.14137
Autor:
Sandisiwe Mangali, Martyna Scibiorek, Frank Kirstein, Amkele Ngomti, Jermaine Khumalo, Sabelo Hadebe, Frank Brombacher, Hlumani Ndlovu, Nontobeko Mthembu
Publikováno v:
The Journal of Allergy and Clinical Immunology
Background B cells play an important role in allergies through secretion of IgE. IL-4 receptor α (IL-4Rα) is key in allergic asthma and regulates type 2 cytokine production, IgE secretion, and airway hyperresponsiveness. IL-4 activation of B cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ad3ec83f4328c2fc8eb949e8974ffd7
https://doi.org/10.1016/j.jaci.2020.12.635
https://doi.org/10.1016/j.jaci.2020.12.635
Autor:
Sabelo Hadebe, Jermaine Khumalo, Amkele Ngomti, Sandisiwe Mangali, Martyna Scibiorek, Frank Brombacher
Publikováno v:
The Journal of Immunology. 204:65.23-65.23
Allergic asthma is a disease driven by T helper 2 (TH2)-type cells secreting interleukin (IL-) 4, 5 and 13. It is characterized by eosinophils, airway hyperesponsiveness (AHR) and IgE secreting B cells. B cells play a role in allergic asthma in an al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07188568286770037811417a03c2929f
https://doi.org/10.4049/jimmunol.204.supp.65.23
https://doi.org/10.4049/jimmunol.204.supp.65.23
Autor:
Diana Hardie, Rudzani Muloiwa, Jermaine Khumalo, Phindile Mteshana, Mark P. Nicol, Colleen Bamford
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173948 (2017)
PLoS ONE
PLoS ONE
Introduction Accurate etiological diagnosis of meningitis is important, but difficult in resource-limited settings due to prior administration of antibiotics and lack of viral diagnostics. We aimed to develop and validate 2 real-time multiplex PCR (R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aebd49e57ca2bf3b01b9ce5032b728de
http://europepmc.org/articles/PMC5367690?pdf=render
http://europepmc.org/articles/PMC5367690?pdf=render