Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Jeri-Anne Lyons"'
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67358 (2013)
BackgroundExperimental autoimmune encephalomyelitis (EAE) is the most commonly studied animal model of multiple sclerosis (MS), a chronic autoimmune demyelinating disorder of the central nervous system. Immunomodulatory and immunosuppressive therapie
Externí odkaz:
https://doaj.org/article/765fac836672469fb2a08f4ad0045aa9
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79002 (2013)
Ischemic stroke affects ∼795,000 people each year in the U.S., which results in an estimated annual cost of $73.7 billion. Calcium is pivotal in a variety of neuronal signaling cascades, however, during ischemia, excess calcium influx can trigger e
Externí odkaz:
https://doaj.org/article/af88263b7ce54a9ab905327b900cac30
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30655 (2012)
BackgroundThe approved immunomodulatory agents for the treatment of multiple sclerosis (MS) are only partially effective. It is thought that the combination of immunomodulatory and neuroprotective strategies is necessary to prevent or reverse disease
Externí odkaz:
https://doaj.org/article/0fc075aa5e884e11a21968ca0c29f637
Autor:
Nancy L Monson, Petra Cravens, Rehana Hussain, Christopher T Harp, Matthew Cummings, Maria de Pilar Martin, Li-Hong Ben, Julie Do, Jeri-Anne Lyons, Amy Lovette-Racke, Anne H Cross, Michael K Racke, Olaf Stüve, Mark Shlomchik, Todd N Eagar
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17103 (2011)
Recent clinical trials have established B cell depletion by the anti-CD20 chimeric antibody Rituximab as a beneficial therapy for patients with relapsing-remitting multiple sclerosis (MS). The impact of Rituximab on T cell responses remains largely u
Externí odkaz:
https://doaj.org/article/7eb457a109ad42ca8f3e5a28c0d1260d
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e12928 (2010)
A strong relationship exists between increased inflammatory cytokines and muscle insulin resistance in obesity. This study focused on identifying a relationship between metabolic propensity and myostatin expression in muscle and spleen cells in respo
Externí odkaz:
https://doaj.org/article/012dd47c48f345f0be5aabd5f26a4408
Publikováno v:
Medicine & Science in Sports & Exercise. 53:122-123
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30cf357b5d86151903fb89a6d3acc2a0
https://doi.org/10.1249/01.mss.0000760564.99937.e3
https://doi.org/10.1249/01.mss.0000760564.99937.e3
Publikováno v:
Medicine & Science in Sports & Exercise. 52:442-442
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34a15ad57ab458ca63634cdf747ad8b1
https://doi.org/10.1249/01.mss.0000678704.96673.37
https://doi.org/10.1249/01.mss.0000678704.96673.37
Publikováno v:
Medicine & Science in Sports & Exercise. 52:78-78
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d26158f90984addfe9eab12ec7983a49
https://doi.org/10.1249/01.mss.0000670892.38427.23
https://doi.org/10.1249/01.mss.0000670892.38427.23
Publikováno v:
The Journal of Immunology. 204:160.8-160.8
Multiple sclerosis (MS) is an autoimmune disease characterized by myelin destruction, neurodegeneration and mitochondrial dysfunction. High production of nitric oxide (NO) by iNOS contributes to the generation of reactive nitrogen species, leading to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::744ea0c45b394ab459cef1a212d5fc35
https://doi.org/10.4049/jimmunol.204.supp.160.8
https://doi.org/10.4049/jimmunol.204.supp.160.8