Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jeremy Yethon"'
Autor:
Leah E. Cole, Jinrong Zhang, Jeremy Yethon, Harry Kleanthous, Natalie G. Anosova, Hubert Lam, Augustus Kesselly
Publikováno v:
Infection and Immunity
Staphylococcus epidermidis is normally a commensal colonizer of human skin and mucus membranes, but, due to its ability to form biofilms on indwelling medical devices, it has emerged as a leading cause of nosocomial infections. Bacteremia or bloodstr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::378319c68be5f89ee1ceb59ff2e43355
https://doi.org/10.1128/iai.01472-15
https://doi.org/10.1128/iai.01472-15
Autor:
Nachum Kaplan, Judd Berman, Elias Bardouniotis, Jeremy Yethon, Barry Hafkin, Donald E. Awrey, Pauls Henry W
Publikováno v:
Journal of Chemotherapy (Florence, Italy)
AFN-1252 is a novel inhibitor of FabI, an essential enzyme in fatty acid biosynthesis in Staphylococcus spp. AFN-1252 exhibits typical MIC(90) values of ≤0·015 μg/ml against diverse clinical isolates of S. aureus, oral absorption, long eliminatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5889345e61026271de1bbf717c7c5a9
https://doi.org/10.1179/1973947812y.0000000063
https://doi.org/10.1179/1973947812y.0000000063
Autor:
Elias Bardouniotis, Nachum Kaplan, Molly B. Schmid, Judd Berman, Donald E. Awrey, Rosanne Thalakada, Mandy Dorsey, Barry Hafkin, Monique Albert, Teresa E. Clarke, Jeremy Yethon, Vladimir Romanov, Pauls Henry W, Jaillal Ramnauth
Publikováno v:
Antimicrobial Agents and Chemotherapy. 56:5865-5874
The mechanism of action of AFN-1252, a selective inhibitor of Staphylococcus aureus enoyl-acyl carrier protein reductase (FabI), which is involved in fatty acid biosynthesis, was confirmed by using biochemistry, macromolecular synthesis, genetics, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e1234a5b194110a296575384bd9fe6c
https://doi.org/10.1128/aac.01411-12
https://doi.org/10.1128/aac.01411-12
Autor:
Omid C. Farokhzad, Mario Perro, Robert Langer, Jeremy Yethon, Andrew M. Tager, Andrew J. Olive, Pamela Basto, Aleksandar F. Radovic-Moreno, Vladimir Vrbanac, Michael N. Starnbach, Georg Stary, Ulrich H. von Andrian, David Alvarez, David C. Gondek, Jinjun Shi
Publikováno v:
Science (New York, N.Y.). 348(6241)
The right combination for protection Despite its prevalence, no vaccine exists to protect against infection with the sexually transmitted bacterium Chlamydia trachomatis . Stary et al. now report on one potential vaccine candidate (see the Perspectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9624759361c512c1cef5782801980b8
https://pubmed.ncbi.nlm.nih.gov/26089500
https://pubmed.ncbi.nlm.nih.gov/26089500
Publikováno v:
Infection and immunity. 82(9)
Biofilm formation on central lines or peripheral catheters is a serious threat to patient well-being. Contaminated vascular devices can act as a nidus for bloodstream infection and systemic pathogen dissemination. Staphylococcal biofilms are the most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e42bf06db55c68f26179a08ae3b0a36
https://pubmed.ncbi.nlm.nih.gov/25878162
https://pubmed.ncbi.nlm.nih.gov/25878162
Pneumolysin (PLY) is a cholesterol-binding, pore-forming protein toxin. It is an important virulence factor of Streptococcus pneumoniae and a key vaccine target against pneumococcal disease. We report a systematic structure-driven approach that solve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::199811ee1759fe1dac3594e3b25c4daa
https://europepmc.org/articles/PMC3069417/
https://europepmc.org/articles/PMC3069417/
Autor:
Svetlana Stegalkina, Hubert Lam, Raymond P. Oomen, Robert L. Charlebois, Harold Kleanthous, Augustus Kesselly, Jeremy Yethon
Publikováno v:
Infection and Immunity. 83:2197-2197
Volume 82, no. 9, p. [3764–3774][1], 2014. Page 3764: The byline and affiliation lines should read as given above. Page 3773, column 1, Acknowledgments. Lines 39–41 should read as follows. “We thank P. D. Fey for strains and plasmids, J. Switze
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdf3d2a5814fb743e37d498a876fa278
https://doi.org/10.1128/iai.00285-15
https://doi.org/10.1128/iai.00285-15