Evasion of immunosurveillance by genomic alterations of PPARγ/RXRα in bladder cancer

Autor: Morgan E. Roberts, Pete Smith, Manav Korpal, Markus Warmuth, Mark Matijevic, Bernhard Kiss, Ming-Hong Hao, Jesse Chow, Zhenhua Jeremy Wu, Ryan Henry, Jian Zou, Peter Fekkes, Nicholas A. Larsen, Pavan Kumar, Mads Daugaard, Lihua Yu, Kristjan Bloudoff, Allison Davis, Victoria Rimkunas, Jaya Julie Joshi, Sean Irwin, Michael Seiler, Craig Furman, Namita Kumar, Laura Corson, Xiaoling Puyang, Peter C. Black, Htoo Zarni Oo, V. Subramanian, Davide Tortora, Anand Selvaraj, Galina Kuznetsov, Hua Yang, Ladan Fazli, Jacob Feala, Chris K. Wang, Roland Seiler, James Douglas, Ping Zhu

Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Korpal, Manav; Puyang, Xiaoling; Jeremy Wu, Zhenhua; Seiler, Roland; Furman, Craig; Oo, Htoo Z; Seiler, Michael; Irwin, Sean; Subramanian, Vanitha; Julie Joshi, Jaya; Wang, Chris K; Rimkunas, Victoria; Tortora, Davide; Yang, Hua; Kumar, Namita; Kuznetsov, Galina; Matijevic, Mark; Chow, Jesse; Kumar, Pavan; Zou, Jian; ... (2017). Evasion of immunosurveillance by genomic alterations of PPARγ/RXRα in bladder cancer. Nature communications, 8(1), p. 103. Nature Publishing Group 10.1038/s41467-017-00147-w
Nature Communications

Muscle-invasive bladder cancer (MIBC) is an aggressive disease with limited therapeutic options. Although immunotherapies are approved for MIBC, the majority of patients fail to respond, suggesting existence of complementary immune evasion mechanisms

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d94e51cb1110677a123f30a37beb148
https://doi.org/10.1038/s41467-017-00147-w