Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jeremy W. Winkler"'
Autor:
Nicholas Wourms, Xavier de la Rosa, Brian E. Sansbury, Gregory S. Keyes, Jeremy W. Winkler, Nan Chiang, David Fichtner, Paul C. Norris, Stephania Libreros, Matthew Spite, Charles N. Serhan
Publikováno v:
Journal of Leukocyte Biology. 103:995-1010
Local production and downstream metabolism of specialized proresolving lipid mediators (SPMs) are pivotal in regulating their biological actions during resolution of inflammation. Resolvin D4 (RvD4: 4S,5R,17S-trihydroxydocosa-6E,8E,10Z,13Z,15E,19Z he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a7b3181a41a5e26dfe834e0196d3942
https://doi.org/10.1002/jlb.3mi0617-254r
https://doi.org/10.1002/jlb.3mi0617-254r
Autor:
Yuhai Zhao, Frederic Calon, Carl Julien, Jeremy W Winkler, Nicos A Petasis, Walter J Lukiw, Nicolas G Bazan
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e15816 (2011)
Neuroprotectin D1 (NPD1) is a stereoselective mediator derived from the omega-3 essential fatty acid docosahexaenoic acid (DHA) with potent inflammatory resolving and neuroprotective bioactivity. NPD1 reduces Aβ42 peptide release from aging human br
Externí odkaz:
https://doaj.org/article/29284e9ca86646f4998ee89a6a7662ec
Autor:
Souheil El-Chemaly, Jesmond Dalli, Jennifer K. Colby, Nicos A. Petasis, Romain A. Colas, Jason Hellmann, Bruce D. Levy, Charles N. Serhan, Matthew Spite, Ye Cui, Raja-Elie E. Abdulnour, Jeremy W. Winkler, Blenda Wong, Ho Pan Sham
Publikováno v:
The American Journal of Pathology. 186:1801-1813
Acute lung injury is a life-threatening condition caused by disruption of the alveolar-capillary barrier leading to edema, influx of inflammatory leukocytes, and impaired gas exchange. Specialized proresolving mediators biosynthesized from essential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0efc025ad6060c8c887749f981c2b11a
https://doi.org/10.1016/j.ajpath.2016.03.011
https://doi.org/10.1016/j.ajpath.2016.03.011
Autor:
Jeremy W, Winkler, Stephania, Libreros, Xavier, De La Rosa, Brian E, Sansbury, Paul C, Norris, Nan, Chiang, David, Fichtner, Gregory S, Keyes, Nicholas, Wourms, Matthew, Spite, Charles N, Serhan
Publikováno v:
Journal of leukocyte biology.
Local production and downstream metabolism of specialized proresolving lipid mediators (SPMs) are pivotal in regulating their biological actions during resolution of inflammation. Resolvin D4 (RvD4: 4S,5R,17S-trihydroxydocosa-6E,8E,10Z,13Z,15E,19Z he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ce9216ec23e8481f7395d485e4b9ac2b
https://pubmed.ncbi.nlm.nih.gov/29377345
https://pubmed.ncbi.nlm.nih.gov/29377345
Publikováno v:
Organic Letters. 15:1424-1427
The first total synthesis of stereochemically pure resolvin D3 and aspirin-triggered resolvin D3 is reported. These enzymatic metabolites of docosahexaenoic acid (DHA) have potent anti-inflammatory and pro-resolving actions. The convergent synthetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f92eb59033bb44c29ba1f5bc3d620e5
https://doi.org/10.1021/ol400484u
https://doi.org/10.1021/ol400484u
Autor:
Chien-Yee C. Cheng, Jesmond Dalli, Nicos A. Petasis, Romain A. Colas, Nan Chiang, Hildur Arnardottir, Jeremy W. Winkler, Charles N. Serhan
Publikováno v:
Chemistry & Biology. 20(2):188-201
SummaryResolvins are a family of n-3 lipid mediators initially identified in resolving inflammatory exudates that temper inflammatory responses to promote catabasis. Here, temporal metabololipidomics with self-limited resolving exudates revealed that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94703fff705e0eacbb1abcf07a3a0b61
Autor:
Julia M. Sanger, Charles N. Serhan, Jeremy W. Winkler, Jesmond Dalli, Chien-Yee C. Cheng, Nan Chiang, Sarah K. Orr, Nicos A. Petasis
Publikováno v:
Scientific Reports
Resolvins of the D-series are specialized pro-resolving lipid mediators that regulate cellular response by orchestrating resolution networks involved in host responses to injury and infection. Here, endogenous resolvin D4 was identified in human tiss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2871b949ea4c8a84a2d58e1c05cbfff5
Autor:
Charles N. Serhan, Yan Lu, Changde Zhang, Nicolas G. Bazan, Min Zhu, Kristal D. Atkins, Tiffany N. Eady, Gabrielle Fredman, Andre Obenaus, Jeremy W. Winkler, Larissa Khoutorova, Nicos A. Petasis, Song Hong, Ludmila Belayev, Bokkyoo Jun
Publikováno v:
Experimental Neurology. 236:122-130
Acute ischemic stroke triggers complex neurovascular, neuroinflammatory and synaptic alterations. Aspirin and docosahexaenoic acid (DHA), an omega-3 essential fatty acid family member, have beneficial effects on cerebrovascular diseases. DHA is the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1db8edca626e0777cd2d9d51751c0ad7
https://doi.org/10.1016/j.expneurol.2012.04.007
https://doi.org/10.1016/j.expneurol.2012.04.007
Autor:
Caleb E. Finch, Todd E. Morgan, Zhi Ning, Jiu-Chiuan Chen, David A. Davis, Yu-Tien Hsu, Michel Baudry, Jeremy W. Winkler, David C. Snyder, Constantinos Sioutas, Winnie Kam, Nahoko Iwata, Nicos A. Petasis, Jeremy A. Tanner
Publikováno v:
Environmental Health Perspectives
Background: Inhalation of airborne particulate matter (PM) derived from urban traffic is associated with pathology in the arteries, heart, and lung; effects on brain are also indicated but are less documented. Objective: We evaluated rodent brain res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dfc4ae1dda238dc6c9645e7621cd496
https://doi.org/10.1289/ehp.1002973
https://doi.org/10.1289/ehp.1002973
Autor:
Sesquile Ramon, Charles N. Serhan, Jørn Eivind Tungen, Julia M. Sanger, Jesmond Dalli, Marius Aursnes, Jeremy W. Winkler, Trond Vidar Hansen
Publikováno v:
The American journal of pathology. 186(4)
Inflammation and its natural resolution are host-protective responses triggered by infection or injury. The resolution phase of inflammation is regulated by enzymatically produced specialized pro-resolving mediators. We recently identified a new clas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::102f4791b66e25d6f3d64d15afb67a37
https://pubmed.ncbi.nlm.nih.gov/26878209
https://pubmed.ncbi.nlm.nih.gov/26878209