Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Jeremy W. Chambers"'
Autor:
Yunke Wang, Samantha Rakela, Jeremy W. Chambers, Zi-Chun Hua, Mark T. Muller, John L. Nitiss, Yuk-Ching Tse-Dinh, Fenfei Leng
Publikováno v:
ACS Omega, Vol 4, Iss 19, Pp 18413-18422 (2019)
Externí odkaz:
https://doaj.org/article/160a7ee6f656476ca20d7340cea6570e
Autor:
Wenjie Wang, Monica Rodriguez-Silva, Arlet M. Acanda de la Rocha, Aizik L. Wolf, Yanhao Lai, Yuan Liu, William C. Reinhold, Yves Pommier, Jeremy W. Chambers, Yuk-Ching Tse-Dinh
Publikováno v:
Cancers, Vol 11, Iss 10, p 1416 (2019)
Glioblastoma (GBM) patients have an estimated survival of ~15 months with treatment, and the standard of care only modestly enhances patient survival. Identifying biomarkers representing vulnerabilities may allow for the selection of efficacious chem
Externí odkaz:
https://doaj.org/article/cea55c7fd8d747758aa75196939f7bb3
Autor:
Eddy E. Alfonso, Zifang Deng, Daniel Boaretto, Becky L. Hood, Stefan Vasile, Layton H. Smith, Jeremy W. Chambers, Prem Chapagain, Fenfei Leng
Publikováno v:
ACS Pharmacology & Translational Science. 5:932-944
Bacterial DNA gyrase, a type IIA DNA topoisomerase that plays an essential role in bacterial DNA replication and transcription, is a clinically validated target for discovering and developing new antibiotics. In this article, based on a supercoiling-
Autor:
Brian C. Bales, Victoria Cotero, Dan E. Meyer, Jeannette C. Roberts, Monica Rodriguez-Silva, Tiberiu M. Siclovan, Jeremy W. Chambers, Michael J. Rishel
Publikováno v:
ACS medicinal chemistry letters. 13(10)
The c-Jun N-terminal kinase 3 (JNK3) is a stress-activated kinase primarily expressed in the brain and implicated as an early mediator of neuronal apoptosis. We sought to develop a PET tracer to visualize pathological JNK3 activation. Because regiona
Autor:
Stefan Vasile, Fenfei Leng, Sabrina Battista, Juliano Freitas, Jeremy W. Chambers, Alyssa Garabedian, Federica D'Alessio, Miriam Romano, Prem P. Chapagain, Linjia Su, Francisco Fernandez-Lima, Alfredo Fusco, Layton H. Smith, Nadezda Bryan, Fabiana Falanga, Lidia Kos
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
The mammalian high mobility group protein AT-hook 2 (HMGA2) is a multi-functional DNA-binding protein that plays important roles in tumorigenesis and adipogenesis. Previous results showed that HMGA2 is a potential therapeutic target of anticancer and
Autor:
Somaiyeh Azmoun, Yenny Fariñas Diaz, Cheuk Y. Tang, Megan Horton, Sean A.P. Clouston, Ben J. Luft, Evelyn J. Bromet, Sam Gandy, Donatella Placidi, Claudia Ambrosi, Lorella Mascaro, Carlo Rodella, Barbara Paghera, Roberto Gasparotti, Jeremy W. Chambers, Kim Tieu, Daniele Corbo, Roberto G. Lucchini
Publikováno v:
Advances in Neurotoxicology ISBN: 9780128191767
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e2ff4e4fc960c632ae8d543693d94b2
https://hdl.handle.net/11379/574605
https://hdl.handle.net/11379/574605
Autor:
Lakshmini, Balachandar, Karla A, Montejo, Eleane, Castano, Melissa, Perez, Carolina, Moncion, Jeremy W, Chambers, J Luis, Lujan, Jorge Riera, Diaz
Publikováno v:
Curr Protoc Neurosci
Astrocytes are actively involved in a neuroprotective role in the brain, which includes scavenging reactive oxygen species to minimize tissue damage. They also modulate neuroinflammation and reactive gliosis prevalent in several brain disorders like
Autor:
Jeremy W. Chambers, Carolina Moncion, Melissa Perez, Karla A. Montejo, Eleane Castano, J. Luis Lujan, Lakshmini Balachandar, Jorge Riera Diaz
Publikováno v:
Current Protocols in Neuroscience. 94
Astrocytes are actively involved in a neuroprotective role in the brain, which includes scavenging reactive oxygen species to minimize tissue damage. They also modulate neuroinflammation and reactive gliosis prevalent in several brain disorders like
Autor:
Meredith K. Loth, Diane B. Re, Tomás R. Guilarte, Sara R. Guariglia, Jennifer L. Dziedzic, Juan Perez, Vanessa Nunes de Paiva, Diana J. Azzam, Jeremy W. Chambers
Publikováno v:
Molecular Neurobiology
In the brain neuropil, translocator protein 18 kDa (TSPO) is a stress response protein that is upregulated in microglia and astrocytes in diverse central nervous system pathologies. TSPO is widely used as a biomarker of neuroinflammation in preclinic
Autor:
Federica D'Alessio, Nadezda Bryan, Sabrina Battista, Jeremy W. Chambers, Prem P. Chapagain, Alfredo Fusco, Linjia Su, Miriam Romano, Fenfei Leng, Francisco Fernandez-Lima, Juliano Freitas, Lidia Kos, Stefan Vasile, Layton H. Smith, Alyssa Garabedian, Fabiana Falanga
The mammalian high mobility group protein AT-hook 2 (HMGA2) is a multi-functional DNA-binding protein which plays important roles in tumorigenesis and adipogenesis. Previous results showed that HMGA2 is a potential therapeutic target of anticancer an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba43c3fddc84510d63ff46cdc6e21479