Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Jeremy V Smedley"'
Autor:
Benjamin Varco-Merth, Morgan Chaunzwa, Derick M Duell, Alejandra Marenco, William Goodwin, Rachel Dannay, Michael Nekorchuk, Danica Shao, Kathleen Busman-Sahay, Christine M Fennessey, Lorna Silipino, Michael Hull, William J Bosche, Randy Fast, Kelli Oswald, Rebecca Shoemaker, Rachele Bochart, Rhonda MacAllister, Caralyn S Labriola, Jeremy V Smedley, Michael K Axthelm, Miles P Davenport, Paul T Edlefsen, Jacob D Estes, Brandon F Keele, Jeffrey D Lifson, Sharon R Lewin, Louis J Picker, Afam A Okoye
Publikováno v:
PLoS Pathogens, Vol 20, Iss 8, p e1012496 (2024)
Persistence of the rebound-competent viral reservoir (RCVR) within the CD4+ T cell compartment of people living with HIV remains a major barrier to HIV cure. Here, we determined the effects of the pan-lymphocyte-depleting monoclonal antibody (mAb) al
Externí odkaz:
https://doaj.org/article/98aa0bf5a0db40c1870449c56d1dca1f
Autor:
Whitney C Weber, Caralyn S Labriola, Craig N Kreklywich, Karina Ray, Nicole N Haese, Takeshi F Andoh, Michael Denton, Samuel Medica, Magdalene M Streblow, Patricia P Smith, Nobuyo Mizuno, Nina Frias, Miranda B Fisher, Aaron M Barber-Axthelm, Kimberly Chun, Samantha Uttke, Danika Whitcomb, Victor DeFilippis, Shauna Rakshe, Suzanne S Fei, Michael K Axthelm, Jeremy V Smedley, Daniel N Streblow
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 11, p e0011742 (2023)
Mayaro virus (MAYV) is a mosquito-transmitted alphavirus that causes debilitating and persistent arthritogenic disease. While MAYV was previously reported to infect non-human primates (NHP), characterization of MAYV pathogenesis is currently lacking.
Externí odkaz:
https://doaj.org/article/9deed2140f2e40a9aabdd1d8e7593a3d
Autor:
Nina Derby, Sreya Biswas, Sofiya Yusova, Cristina Luevano-Santos, Maria Cristina Pacheco, Kimberly A. Meyer, Brooke I. Johnson, Miranda Fischer, Katherine A. Fancher, Cole Fisher, Yohannes M. Abraham, Conor J. McMahon, Savannah S. Lutz, Jeremy V. Smedley, Benjamin J. Burwitz, Donald L. Sodora
Publikováno v:
Viruses, Vol 16, Iss 2, p 296 (2024)
Metabolic-dysfunction-associated fatty liver disease (MAFLD) is a major cause of morbidity and mortality in HIV-infected individuals, even those receiving optimal antiretroviral therapy. Here, we utilized the SIV rhesus macaque model and advanced lap
Externí odkaz:
https://doaj.org/article/cf243f8ab54e4cc8859bf12d3cd45809
Autor:
Rachele M. Bochart, Kimberly Armantrout, Hugh Crank, Rachael Tonelli, Christine Shriver-Munsch, Tonya Swanson, Miranda Fischer, Helen Wu, Michael Axthelm, Jonah Sacha, Jeremy V. Smedley
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Methicillin-resistant Staphylococcus aureus (MRSA) is a S. aureus strain with resistance to beta-lactam antibiotics, making it a global human and veterinary health concern. Specifically, immunosuppressed patients have a remarkably higher risk of clin
Externí odkaz:
https://doaj.org/article/100d9e5d6af848b19bf6aa76a0f55030
Autor:
Sreya Biswas, Lauren N. Rust, Jochen M. Wettengel, Sofiya Yusova, Miranda Fischer, Julien N. Carson, Josie Johnson, Lei Wei, Trason Thode, Mohan R. Kaadige, Sunil Sharma, Majd Agbaria, Benjamin N. Bimber, Thomas Tu, Ulrike Protzer, Alexander Ploss, Jeremy V. Smedley, Gershon Golomb, Jonah B. Sacha, Benjamin J. Burwitz
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Here, Biswas et al. present and characterize a second-generation model of HBV infection in rhesus macaques, showing that extended infection requires suppression of host immunity.
Externí odkaz:
https://doaj.org/article/6626a89b33b1442db7ec196681607c1f
Autor:
Rachele M Bochart, Kathleen Busman-Sahay, Stephen Bondoc, David W Morrow, Alexandra M Ortiz, Christine M Fennessey, Miranda B Fischer, Oriene Shiel, Tonya Swanson, Christine M Shriver-Munsch, Hugh B Crank, Kimberly M Armantrout, Aaron M Barber-Axthelm, Charlotte Langner, Cassandra R Moats, Caralyn S Labriola, Rhonda MacAllister, Michael K Axthelm, Jason M Brenchley, Brandon F Keele, Jacob D Estes, Scott G Hansen, Jeremy V Smedley
Publikováno v:
PLoS Pathogens, Vol 19, Iss 4, p e1011343 (2023)
[This corrects the article DOI: 10.1371/journal.ppat.1009565.].
Externí odkaz:
https://doaj.org/article/642da0372b874e13b89429f1a824dff1
Autor:
Françoise Haeseleer, Yoshinori Fukazawa, Haesun Park, Benjamin Varco-Merth, Blake J. Rust, Jeremy V. Smedley, Karsten Eichholz, Christopher W. Peterson, Rosemarie Mason, Hans-Peter Kiem, Mario Roederer, Louis J. Picker, Afam A. Okoye, Lawrence Corey
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 22, Iss , Pp 304-319 (2021)
Chimeric antigen receptor (CAR) T cell therapies are being investigated as potential HIV cures and designed to target HIV reservoirs. Monoclonal antibodies (mAbs) targeting the simian immunodeficiency virus (SIV) envelope allowed us to investigate th
Externí odkaz:
https://doaj.org/article/2e4204042ab849e8adedcd5d6bbb820e
Autor:
Cassandra Moats, Kimberly Cook, Kimberly Armantrout, Hugh Crank, Samantha Uttke, Kelly Maher, Rachele M. Bochart, George Lawrence, Michael K. Axthelm, Jeremy V. Smedley
Publikováno v:
PLoS ONE, Vol 17, Iss 4 (2022)
Surgical antimicrobial prophylaxis is indicated when performing contaminated surgeries, when specific surgical implants are placed, and for prolonged surgical procedures. Unnecessary prophylactic antibiotics are often utilized for macaque surgeries,
Externí odkaz:
https://doaj.org/article/37b00141267b4db9bd86f3d3a1066686
Autor:
Rachele M Bochart, Kathleen Busman-Sahay, Stephen Bondoc, David W Morrow, Alexandra M Ortiz, Christine M Fennessey, Miranda B Fischer, Oriene Shiel, Tonya Swanson, Christine M Shriver-Munsch, Hugh B Crank, Kimberly M Armantrout, Aaron M Barber-Axthelm, Charlotte Langner, Cassandra R Moats, Caralyn S Labriola, Rhonda MacAllister, Michael K Axthelm, Jason M Brenchley, Brandon F Keele, Jacob D Estes, Scott G Hansen, Jeremy V Smedley
Publikováno v:
PLoS Pathogens, Vol 17, Iss 5, p e1009565 (2021)
Here, we assessed the efficacy of a short-course multimodal therapy (enrofloxacin, azithromycin, fenbendazole, and paromomycin) to eliminate common macaque endemic pathogens (EPs) and evaluated its impact on gastrointestinal (GI) microbiota, mucosal
Externí odkaz:
https://doaj.org/article/992f54c157d640b18472778fff3dc3c7
Autor:
Helen L. Wu, Kathleen Busman-Sahay, Whitney C. Weber, Courtney M. Waytashek, Carla D. Boyle, Katherine B. Bateman, Jason S. Reed, Joseph M. Hwang, Christine Shriver-Munsch, Tonya Swanson, Mina Northrup, Kimberly Armantrout, Heidi Price, Mitch Robertson-LeVay, Samantha Uttke, Mithra R. Kumar, Emily J. Fray, Sol Taylor-Brill, Stephen Bondoc, Rebecca Agnor, Stephanie L. Junell, Alfred W. Legasse, Cassandra Moats, Rachele M. Bochart, Joseph Sciurba, Benjamin N. Bimber, Michelle N. Sullivan, Brandy Dozier, Rhonda P. MacAllister, Theodore R. Hobbs, Lauren D. Martin, Angela Panoskaltsis-Mortari, Lois M.A. Colgin, Robert F. Siliciano, Janet D. Siliciano, Jacob D. Estes, Jeremy V. Smedley, Michael K. Axthelm, Gabrielle Meyers, Richard T. Maziarz, Benjamin J. Burwitz, Jeffrey J. Stanton, Jonah B. Sacha
Publikováno v:
Immunity.