Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Jeremy Troy Smith"'
Autor:
Da Young Oh, Kristen P. Tolson, Alexander S. Kauffman, Jeremy Troy Smith, Evelyn Walenta, Reanna B. Liaw, Andrew Wolfe, Rishi Savur, Julie Ann P. De Bond, Nuha Marooki, Shannon B. Z. Stephens
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, vol 34, iss 1
FASEB J
FASEB J
The peptide kisspeptin and its receptor, Kiss1r, act centrally to stimulate reproduction. Evidence indicates that kisspeptin signaling is also important for body weight (BW) and metabolism. We recently reported that Kiss1r KO mice develop obesity, al
Publikováno v:
Journal of the Endocrine Society
The neuropeptide kisspeptin, encoded by the Kiss1 gene, binds the G- protein-coupled receptor Kiss1r (also known as GPR54) and is a novel player in the delicate balance of energy intake and expenditure. Mice that have a dysfunctional gene for Kiss1r
Publikováno v:
Physiological Reports. 8
Expression of particular genes in hypothami of ewes was measured across the natural pubertal transition by in situ hybridization. The ewes were allocated to three groups (n = 4); prepubertal, postpubertal and postpubertally gonadectomized (GDX). Prep
Publikováno v:
Journal of thermal biology. 90
Kisspeptin, a neuropeptide that activates gonadotropin-releasing hormone (GnRH) neurons, has also been implicated as a regulator of energy balance. Kisspeptin receptor (Kiss1r) knockout (KO) mice display an obese phenotype in adulthood compared to wi
Publikováno v:
Journal of Endocrinology. 238:R173-R183
Kisspeptin is a neuropeptide with a critical role in the function of the hypothalamic–pituitary–gonadal (HPG) axis. Kisspeptin is produced by two major populations of neurons located in the hypothalamus, the rostral periventricular region of the
Autor:
Duane H. Keisler, Jeremy Troy Smith, Jay A Daniel, Casey C. Read, Brian K Whitlock, Arthur D. Zimmerman, Melaney A Jones, Iain J. Clarke, Theodore H. Elsasser, Chad D. Foradori, Barbara P Steele, James L. Sartin
Publikováno v:
Endocrinology. 158:3526-3539
Although kisspeptin is the primary stimulator of gonadotropin-releasing hormone secretion and therefore the hypothalamic-pituitary-gonadal axis, recent findings suggest kisspeptin can also regulate additional neuroendocrine processes including releas
Autor:
Jeremy Troy Smith, Lique M. Coolen, Michael N. Lehman, Iain J. Clarke, Robert L. Goodman, Peyton W. Weems
Publikováno v:
Endocrinology. 158:831-841
Seasonal reproduction in sheep is primarily due to a dramatic increase in the ability of estradiol (E2) to inhibit the pulsatile secretion of gonadotropin-releasing hormone (GnRH) during the nonbreeding season [anestrus (ANS)]. Recent findings sugges
Publikováno v:
Mol Cell Endocrinol
Kisspeptin and its receptor, Kiss1r, act in centrally to stimulate reproduction. Recent evidence indicates that kisspeptin is also important for body weight and metabolism, as whole-body Kiss1r KO mice, developed with gene trap technology, display ob
Autor:
Jeremy Troy Smith, Iain J. Clarke
Publikováno v:
Bioscientifica Proceedings.
Sheep are seasonal breeders and reproductive status is controlled by photoperiod. Recent recognition of the significant role for kisspeptin and gonadotropin inhibitory hormone (GnIH) in the regulation of gonadotropin releasing hormone (GnRH) cells ha
Autor:
Trina Jorre de St Jorre, P.A.R. Hawken, Dominique Blache, Graeme Martin, Christopher J. Scott, Jennifer Rodger, Jeremy Troy Smith, Tammi Esmaili
Publikováno v:
Reproduction, fertility, and development. 31(11)
The neuroendocrine response of female sheep to a novel male involves neural activation in the hypothalamus. However, if males are removed, the gonadotrophic signal declines, so the neural activity is likely to change. We examined Fos-immunoreactive (