Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Jeremy Tang"'
1
Akademický článek
Protein-lysine methyltransferases G9a and GLP1 promote responses to DNA damage
Autor: Vasudeva Ginjala, Lizahira Rodriguez-Colon, Bratati Ganguly, Prawallika Gangidi, Paul Gallina, Husam Al-Hraishawi, Atul Kulkarni, Jeremy Tang, Jinesh Gheeya, Srilatha Simhadri, Ming Yao, Bing Xia, Shridar Ganesan
Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Upon induction of DNA breaks, ATM activation leads to a cascade of local chromatin modifications that promote efficient recruitment of DNA repair proteins. Errors in this DNA repair pathway lead to genomic instability and cancer predispositi
Externí odkaz: https://doaj.org/article/4981bcc1f4d943a6816b9de984a70298
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4
Akademický článek
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6
Protein-lysine methyltransferases G9a and GLP1 promote responses to DNA damage
Autor: Ming Yao, Srilatha Simhadri, Atul Kulkarni, Paul Gallina, Vasudeva Ginjala, Lizahira Rodriguez-Colon, Bratati Ganguly, Prawallika Gangidi, Jeremy Tang, Husam Al-Hraishawi, Jinesh S. Gheeya, Shridar Ganesan, Bing Xia
Publikováno v: Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Upon induction of DNA breaks, ATM activation leads to a cascade of local chromatin modifications that promote efficient recruitment of DNA repair proteins. Errors in this DNA repair pathway lead to genomic instability and cancer predisposition. Here,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b863170c4eedd9239721cd8bef438375
https://doi.org/10.1038/s41598-017-16480-5
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7
Akademický článek
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8
Abstract A81: Identification of reversion mutation by next-generation sequencing in PARP-inhibitor resistant BRCA2 associated breast cancer: Defects in mis-match repair and acquired chemoresistance in breast cancer
Autor: Serena Wong, Lorna Rodriguez, Deborah Toppmeyer, Kim M. Hirshfield, Jinesh S. Gheeya, Jeremy Tang, Shridar Ganesan, Joseph Ho
Publikováno v: Molecular Cancer Therapeutics. 14:A81-A81
Women harboring germline mutations in BRCA2 have an increased risk of developing breast and ovarian cancers. The cancers that arise have undergone loss of the wildtype BRCA2 allele, consistent with BRCA2 functioning as a tumor suppressor. The DNA rep
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::63b8ebbb48270689a01597418f2bf2bd
https://doi.org/10.1158/1535-7163.targ-15-a81
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9
Abstract C133: Aresenic Trioxide as targeted therapy for cancers harboring TRIM33-RET -fusion proteins
Autor: Kim M. Hirshfield, Jeremy Tang, Shridar Ganesan, Lorna Rodriguez, Atul Kulkarni
Publikováno v: Molecular Cancer Therapeutics. 14:C133-C133
Chromosomal rearrangements are genomic events that can result in oncogenic gene fusions that are important drivers of tumerogenesis in multiple human cancers. Gene re-arrangements involving RET proto-oncogene were initially reported in papillary thyr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::97ddec185ab37d260b6fea0b12083013
https://doi.org/10.1158/1535-7163.targ-15-c133
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