Výsledky vyhledávání - "Jeremy T. Rahkola"

Akademický článek

Ena/VASP Protein-Mediated Actin Polymerization Contributes to Naïve CD8+ T Cell Activation and Expansion by Promoting T Cell–APC Interactions In Vivo

Autor: Monique M. Waldman, Jeremy T. Rahkola, Ashton L. Sigler, Jeffrey W. Chung, Benjamin A. S. Willett, Ross M. Kedl, Rachel S. Friedman, Jordan Jacobelli

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

Naïve T cell activation in secondary lymphoid organs such as lymph nodes (LNs) occurs upon recognition of cognate antigen presented by antigen presenting cells (APCs). T cell activation requires cytoskeleton rearrangement and sustained interactions

Externí odkaz: https://doaj.org/article/2f94a80c66674531848e898f60d561a1

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Akademický článek

Hematopoietic stem cells produce intermediate lineage adipocyte progenitors that simultaneously express both myeloid and mesenchymal lineage markers in adipose tissue

Autor: Kathleen M. Gavin, Timothy M. Sullivan, Joanne K. Maltzahn, Jeremy T. Rahkola, Alistair S. Acosta, Wendy M. Kohrt, Susan M. Majka, Dwight J. Klemm

Publikováno v: Adipocyte, Vol 10, Iss 1, Pp 394-407 (2021)

Some adipocytes are produced from bone marrow hematopoietic stem cells. In vitro studies previously indicated that these bone marrow-derived adipocytes (BMDAs) were generated from adipose tissue macrophage (ATM) that lose their hematopoietic markers

Externí odkaz: https://doaj.org/article/4714b14b96094ba6b06e0710b06ad688

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Akademický článek

Elevated Detection of Dual Antibody B Cells Identifies Lupus Patients With B Cell-Reactive VH4-34 Autoantibodies

Autor: Jacob N. Peterson, Susan A. Boackle, Sophina H. Taitano, Allison Sang, Julie Lang, Margot Kelly, Jeremy T. Rahkola, Anjelica M. Miranda, Ryan M. Sheridan, Joshua M. Thurman, V. Koneti Rao, Raul M. Torres, Roberta Pelanda

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

About 5% of B cells in healthy mice and humans are allelically or isotypically included and hence co-express two different antibodies. In mice, dual antibody B cells (B2R) expand with systemic autoimmunity, co-express autoreactive and non-autoreactiv

Externí odkaz: https://doaj.org/article/5f1afc36ba8f45bcab70e6f4f8f6adb2

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Impact of HIV-1 Infection and Antigen Class on T Follicular Helper Cell Responses to Pneumococcal Polysaccharide–Protein Conjugate Vaccine-13

Autor: Edward M. Gardner, Lindsay K. Nicholson, Edward N. Janoff, James Scott, Vibha Jha, Jordan Jacobelli, Jeremy T Rahkola, Mandy Borgeson, Harsh Pratap

Publikováno v: The Journal of Immunology. 206:2402-2411

Pneumococcal infections are common and serious complications of HIV-1 disease. Prevention has been compromised by the limited magnitude and quality of Ab responses to T cell–independent type 2 pneumococcal capsular polysaccharides (PPS). The pneumo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7da4b633bbd4eead67935b0ac2cb8de
https://doi.org/10.4049/jimmunol.2001133

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Hematopoietic stem cells produce intermediate lineage adipocyte progenitors that simultaneously express both myeloid and mesenchymal lineage markers in adipose tissue

Autor: Susan M. Majka, Alistair S Acosta, Kathleen M. Gavin, Wendy M. Kohrt, Timothy M Sullivan, Dwight J. Klemm, Joanne K Maltzahn, Jeremy T Rahkola

Publikováno v: Adipocyte, Vol 10, Iss 1, Pp 394-407 (2021)
Adipocyte
article-version (VoR) Version of Record

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65070fbf808acccb282484863729c2b8
https://doaj.org/article/4714b14b96094ba6b06e0710b06ad688

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Akademický článek

Mother-to-Child HIV-1 Transmission Events Are Differentially Impacted by Breast Milk and Its Components from HIV-1-Infected Women.

Autor: Ruizhong Shen, Jenna Achenbach, Yue Shen, Jana Palaia, Jeremy T Rahkola, Heidi J Nick, Lesley E Smythies, Michelle McConnell, Mary G Fowler, Phillip D Smith, Edward N Janoff

Publikováno v: PLoS ONE, Vol 10, Iss 12, p e0145150 (2015)

Breast milk is a vehicle of infection and source of protection in post-natal mother-to-child HIV-1 transmission (MTCT). Understanding the mechanism by which breast milk limits vertical transmission will provide critical insight into the design of pre

Externí odkaz: https://doaj.org/article/14a8ae869a6046ccbf4a3ffb0f89c72a

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Ena/VASP protein-mediated actin polymerization contributes to naive CD8+ T cell activation and expansion by promoting T cell-APC interactions in vivo

Autor: Monique M Waldman, Jeremy T. Rahkola, Benjamin A.S. Willett, Jeffrey W. Chung, Ashton L. Sigler, Rachel S. Friedman, Ross M. Kedl, Jordan Jacobelli

Publikováno v: The Journal of Immunology. 208:110.17-110.17

Naive T cell activation in secondary lymphoid organs such as lymph nodes (LNs) occurs upon recognition of cognate antigens presented by antigen presenting cells (APCs). T cell activation requires cytoskeleton rearrangement and sustained interactions

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aedee84f12eed03b8883ac05b0cb24af
https://doi.org/10.4049/jimmunol.208.supp.110.17

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Mechanism and inhibition of Streptococcus pneumoniae IgA1 protease

Autor: Todd Holyoak, Norman Tran, Jeremy T Rahkola, Zhiming Wang, Ying-Chih Chi, Edward N. Janoff, Elan Z. Eisenmesser, Jasmina S. Redzic, Hongjin Zheng

Publikováno v: Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)

Opportunistic pathogens such as Streptococcus pneumoniae secrete a giant metalloprotease virulence factor responsible for cleaving host IgA1, yet the molecular mechanism has remained unknown since their discovery nearly 30 years ago despite the poten

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74ce133dbdf012ae5771dbb5dae87c69
https://pubmed.ncbi.nlm.nih.gov/33247098

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