Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Jeremy Segal"'
Real world predictors of response and 24-month survival in high-grade TP53-mutated myeloid neoplasms
Autor:
Amandeep Kaur, Alexandra E. Rojek, Emily Symes, Mariam T. Nawas, Anand A. Patel, Jay L. Patel, Payal Sojitra, Barina Aqil, Madina Sukhanova, Megan E. McNerney, Leo P. Wu, Aibek Akmatbekov, Jeremy Segal, Melissa Y. Tjota, Sandeep Gurbuxani, Jason X. Cheng, Su-Yeon Yeon, Harini V. Ravisankar, Carrie Fitzpatrick, Angela Lager, Michael W. Drazer, Caner Saygin, Pankhuri Wanjari, Panagiotis Katsonis, Olivier Lichtarge, Jane E. Churpek, Sharmila B. Ghosh, Ami B. Patel, Madhu P. Menon, Daniel A. Arber, Peng Wang, Girish Venkataraman
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Current therapies for high-grade TP53-mutated myeloid neoplasms (≥10% blasts) do not offer a meaningful survival benefit except allogeneic stem cell transplantation in the minority who achieve a complete response to first line therapy (CR1
Externí odkaz:
https://doaj.org/article/c0e050742d8c498c9f4fc3640be68aa0
Autor:
Jacobi B. Hines, MD, Benjamin C. Bowar, PharmD, Margaret Colleton, MMS, Lydia Chelala, MD, Peng Wang, MD, Angad A. Chadha, MD, Jeremy Segal, MD, Christine M. Bestvina, MD
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 11, Pp 100724- (2024)
RET fusions are present in 1% to 2% of NSCLCs. Although RET inhibitors like selpercatinib are effective, resistance inevitably develops. We present the case of a 28-year-old female with recurrent NSCLC and a CCDC6::RET fusion treated with selpercatin
Externí odkaz:
https://doaj.org/article/dc5a5a8ec8b44c4a9204b2a1fb65c01b
Autor:
Namrata Setia, Daniela delGaudio, Priscilla Kandikatla, Kelly Arndt, Melissa Tjota, Peng Wang, Jeremy Segal, Mir Alikhan, John Hart
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 10, Iss 1, Pp n/a-n/a (2024)
Abstract A whole exome sequencing (WES)‐driven approach to uncover the etiology of unexplained inflammatory gastritides has been underutilized by surgical pathologists. Here, we discovered the pathobiology of an unusual chronic atrophic gastritis i
Externí odkaz:
https://doaj.org/article/dc744fe0cfff41f181cfcc1fb4492a2e
Autor:
Peng Wang, Jeremy Segal, Michael W. Drazer, Girish Venkataraman, Daniel A. Arber, Sandeep Gurbuxani
Publikováno v:
eJHaem, Vol 3, Iss 3, Pp 962-965 (2022)
Externí odkaz:
https://doaj.org/article/7afa32af25924f69b70d28bb7d82c861
Autor:
Mustafa Fatih Abasiyanik, Blake Flood, Jing Lin, Sefika Ozcan, Sherin J. Rouhani, Athalia Pyzer, Jonathan Trujillo, Chaojie Zhen, Ping Wu, Stephen Jumic, Andrew Wang, Thomas F. Gajewski, Peng Wang, Madeline Hartley, Bekim Ameti, Rachael Niemiec, Marian Fernando, Vasudha Mishra, Peter Savage, Bulent Aydogan, Cindy Bethel, Scott Matushek, Kathleen G. Beavis, Nishant Agrawal, Jeremy Segal, Savaş Tay, Evgeny Izumchenko
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Saliva has significant advantages as a test medium for detection of SARS-CoV-2 infection in patients, such as ease of collection, minimal requirement of supplies and trained personnel, and safety. Comprehensive validation in a large cohort o
Externí odkaz:
https://doaj.org/article/10e5c7f5048c47d29112a27e324f9fe8
Autor:
Kristina Doytcheva, Alexander J. Gallan, Peng Wang, Pankhuri Wanjari, Jeremy Segal, Tatjana Antic
Publikováno v:
Human Pathology. 136:25-33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6454e86a7c8c1af1a79fa7e96d4b2bba
https://doi.org/10.1016/j.humpath.2023.03.008
https://doi.org/10.1016/j.humpath.2023.03.008
Autor:
Faiza Siddiqui, Vanessa Perez Silos, Kennosuke Karube, Suleyman Yasin Goksu, Srinath Nandakumar, Caner Saygin, Oluwakemi Onajin, Swetha S. Prabu, Sandeep Gurbuxani, Daniel A. Arber, Melissa Tjota, Jeremy Segal, Sonali M. Smith, Carlos A. Murga-Zamalloa, Girish Venkataraman
Publikováno v:
Human Pathology. 125:48-58
Normal T cells express high levels of B-cell lymphoma-2 (BCL2) protein, and data regarding BCL2 expression status and its diagnostic utility in T-cell lymphoma are scarce. We evaluated BCL2 expression in a series of mature T-cell lymphoproliferations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bd7f51adca209d4e204acf1c69d5eb1
https://doi.org/10.1016/j.humpath.2022.04.002
https://doi.org/10.1016/j.humpath.2022.04.002
Autor:
Heather I-Hsuan Chen-Yost, Melissa Y Tjota, Guimin Gao, Owen Mitchell, Hedy Kindler, Jeremy Segal, Aliya N Husain, Jeffrey Mueller, Jefree J Schulte
Publikováno v:
American Journal of Clinical Pathology.
Objectives Mesothelioma is a lethal disease that arises from the serosal lining of organ cavities. Several recurrent alterations have been observed in pleural and peritoneal mesotheliomas, including in BAP1, NF2, and CDKN2A. Although specific histo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d48fea76d31c6e551e5fb945f6d9cbea
https://doi.org/10.1093/ajcp/aqad041
https://doi.org/10.1093/ajcp/aqad041
Autor:
Michael Wang, Y. Lynn Wang, Qing Yi, Laura Lam, Yiping Shao, Steven Y. Huang, Selvi Thirumurthi, Makhdum Ahmed, Maria Badillo, Lei Li, Jacqueline Wang, Bingliang Fang, Jack Wang, Carrie Li, Wenjing Tao, Zhihong Chen, Hui Guo, Shengjian Huang, Yang Liu, Onyekachukwu Oriabure, Wendy Chen, Shruti Sharma, Shawana Richard, David Santos, Shouhao Zhou, Shaoying Li, Jeremy Segal, Sabah Kadri, Lan Pham, Taylor Bell, Hui Zhang, Krystle Nomie, Leo Zhang
A, Schematic describing the primary B-cell lymphoma PDX SCID/NSG-hu mouse model. Six-to 8-week-old male NSG or CB-17 SCID mice were implanted with human fetal bone. Approximately 4 to 6 weeks following bone implantation, one injection of 5 Ã- 106 pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56f40caed24f874830da4da33c8347e6
https://doi.org/10.1158/1078-0432.22467500.v1
https://doi.org/10.1158/1078-0432.22467500.v1
Autor:
Pamela B. Conley, John T. Curnutte, Glenn Michelson, Y. Lynn Wang, Jeremy Segal, Pin Lu, Sabah Kadri, Kenneth Der, Janet M. Leeds, Matt Birrell, Anjali Pandey, Andreas Betz, Jiajia Feng, Greg P. Coffey
Purpose:Preclinical studies suggest SYK and JAK contribute to tumor-intrinsic and microenvironment-derived survival signals. The pharmacodynamics of cerdulatinib, a dual SYK/JAK inhibitor, and associations with tumor response were investigated.Patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::718a86465004bc70185ecc77b0994502
https://doi.org/10.1158/1078-0432.c.6526856
https://doi.org/10.1158/1078-0432.c.6526856