Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jeremy Schreiner"'
Autor:
Yeongjun Jang, Liana Fasching, Taejeong Bae, Livia Tomasini, Jeremy Schreiner, Anna Szekely, Thomas V Fernandez, James F Leckman, Flora M Vaccarino, Alexej Abyzov
Publikováno v:
Nucleic Acids Research.
Mosaic mutations can be used to track cell ancestries and reconstruct high-resolution lineage trees during cancer progression and during development, starting from the first cell divisions of the zygote. However, this approach requires sampling and a
Autor:
Simone Tomasi, James F. Leckman, Flora M. Vaccarino, Nikolaos Vasmatzis, Taejeong Bae, Anna Szekely, Melanie V. Brady, Yeongjun Jang, Yifan Wang, Vivekananda Sarangi, Thomas V. Fernandez, Liana Fasching, Alexej Abyzov, Livia Tomasini, Jeremy Schreiner
Publikováno v:
Science
Post-zygotic mosaic mutations can be used to track cell lineages in humans. By using cell cloning and induced pluripotent cell lines, we analyzed early cell lineages in two living individuals (a patient and a control), and a postmortem human specimen