Decoupling copolymer, lipid and carbon nanotube interactions in hybrid, biomimetic vesicles

Autor: Jeremy Sanborn, Jonathan R. I. Lee, Aleksandr Noy, Helgi I. Ingólfsson, Tony van Buuren, Thomas M. Weiss, Timothy S. Carpenter, Ramya H. Tunuguntla, Joshua A. Hammons, Yun Chiao Yao

Publikováno v: Nanoscale. 12:6545-6555

Bilayer vesicles that mimic a real biological cell can be tailored to carry out a specific function by manipulating the molecular composition of the amphiphiles. These bio-inspired and bio-mimetic structures are increasingly being employed for a numb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9bc5aec05ae1b7a69ec0ce266280ec7
https://doi.org/10.1039/c9nr09973e

Carbon Nanotube Porins in Amphiphilic Block Copolymers as Fully Synthetic Mimics of Biological Membranes

Autor: Aleksandr Noy, Christina C. Newcomb, Jeremy Sanborn, Anthony van Buuren, James J. De Yoreo, Joshua A. Hammons, Atul N. Parikh, Ramya H. Tunuguntla, Xi Chen, Jennifer A. Soltis, Yun Chiao Yao, Yuliang Zhang

Publikováno v: Advanced materials (Deerfield Beach, Fla.). 30(51)

Biological membranes provide a fascinating example of a separation system that is multifunctional, tunable, precise, and efficient. Biomimetic membranes, which mimic the architecture of cellular membranes, have the potential to deliver significant im

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6948b836ce2e71fec501e32dc6dfb66
https://pubmed.ncbi.nlm.nih.gov/30368926

Transient pearling and vesiculation of membrane tubes under osmotic gradients

Autor: Jeremy Sanborn, Kamila Oglęcka, Atul N. Parikh, Rachel Kraut

Publikováno v: Faraday Discuss.. 161:167-176

We report the experimental observation of osmotically induced transient pearling instabilities in vesicular membranes. Giant phospholipid vesicles subjected to negative osmotic gradient, which drives the influx of water in to the vesicular interior,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::096a3992e50d937da4aa95e87e220265
https://doi.org/10.1039/c2fd20116j

Protein receptor-independent plasma membrane remodeling by HAMLET:a tumoricidal protein-lipid complex

Autor: Aftab Nadeem, Stine F. Pedersen, Ho C S James, Catharina Svanborg, Atul N. Parikh, Matti Lam, Douglas L. Gettel, Viviane N. Ngassam, Jeremy Sanborn, Thomas Kjær Klausen, Anna Rydström

Publikováno v: Nadeem, A, Sanborn, J, Gettel, D L, Ho C.S., J, Rydström, A, Ngassam, V N, Klausen, T K, Pedersen, S H F, Lam, M, Parikh, A N & Svanborg, C 2015, ' Protein receptor-independent plasma membrane remodeling by HAMLET : a tumoricidal protein-lipid complex ', Scientific Reports, vol. 5, 16432 . https://doi.org/10.1038/srep16432
Scientific Reports
Scientific reports, vol 5, iss 1

A central tenet of signal transduction in eukaryotic cells is that extra-cellular ligands activate specific cell surface receptors, which orchestrate downstream responses. This ‘’protein-centric” view is increasingly challenged by evidence for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::649326e26f50e5f205e548ff14bb7b01
https://curis.ku.dk/portal/da/publications/protein-receptorindependent-plasma-membrane-remodeling-by-hamlet(4622294d-6eb5-415e-9b50-9ce9455b163a).html

Mixing, diffusion, and percolation in binary supported membranes containing mixtures of lipids and amphiphilic block copolymers

Autor: Mira A. Patel, Douglas L. Gettel, Bo Liedberg, Madhavan Nallani, Atul N. Parikh, Hans-Peter M. de Hoog, Jeremy Sanborn

Publikováno v: Journal of the American Chemical Society. 136(29)

Substrate-mediated fusion of small polymersomes, derived from mixtures of lipids and amphiphilic block copolymers, produces hybrid, supported planar bilayers at hydrophilic surfaces, monolayers at hydrophobic surfaces, and binary monolayer/bilayer pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca1bc13e09a7f4ed9add871d640859c4
https://pubmed.ncbi.nlm.nih.gov/25003585