Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jeremy S. Haley"'
Autor:
Kelvin C. de Andrade, Natasha T. Strande, Jung Kim, Jeremy S. Haley, Jessica N. Hatton, Megan N. Frone, Payal P. Khincha, Gretchen M. Thone, Uyenlinh L. Mirshahi, Cynthia Schneider, Heena Desai, James T. Dove, Diane T. Smelser, Arnold J. Levine, Kara N. Maxwell, Douglas R. Stewart, David J. Carey, Sharon A. Savage
Publikováno v:
HGG Advances, Vol 5, Iss 1, Pp 100242- (2024)
Summary: Pathogenic or likely pathogenic (P/LP) germline TP53 variants are the primary cause of Li-Fraumeni syndrome (LFS), a hereditary cancer predisposition disorder characterized by early-onset cancers. The population prevalence of P/LP germline T
Externí odkaz:
https://doaj.org/article/addc5e489bb345e3861d80415655e2ce
Autor:
Hannah S. Mirshahi, Jeremy S. Haley, Diane T. Smelser, Evan J. Ryer, James R. Elmore, David J. Carey
Publikováno v:
JVS - Vascular Science, Vol 4, Iss , Pp 100164- (2023)
Externí odkaz:
https://doaj.org/article/2591899d4dc045ec8290887647fda5ab
Autor:
Kathleen M. Kokolus, Jeremy S. Haley, Emily J. Koubek, Raghavendra Gowda, Saketh S. Dinavahi, Arati Sharma, David F. Claxton, Klaus F. Helm, Joseph J. Drabick, Gavin P. Robertson, Jeffrey D. Neighbors, Raymond J. Hohl, Todd D. Schell
Publikováno v:
OncoImmunology, Vol 8, Iss 2 (2019)
Metastatic melanoma is a significant clinical problem with a 5-year survival rate of only 15–20%. Recent approval of new immunotherapies and targeted inhibitors have provided much needed options for these patients, in some cases promoting dramatic
Externí odkaz:
https://doaj.org/article/5046be52e262417b833f22a08b249b8a
Autor:
David B. Beck, Dale L. Bodian, Vandan Shah, Uyenlinh L. Mirshahi, Jung Kim, Yi Ding, Natasha T. Strande, Anna Cantor, Jeremy S. Haley, Adam Cook, Wesley Hill, Peter C. Grayson, Marcela A. Ferrada, Daniel L. Kastner, David J. Carey, Douglas R. Stewart
ImportanceVEXAS (vacuoles, E1-ubiquitin-activating enzyme, X-linked, autoinflammatory, somatic) syndrome is a disease with rheumatologic and hematologic features caused by somatic variants in UBA1. Pathogenic variants are associated with a broad spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::542c4a839bac26c694dd2056948f155f
https://doi.org/10.1101/2022.07.27.22277962
https://doi.org/10.1101/2022.07.27.22277962
Autor:
Esteban Astiazaran-Symonds, Jung Kim, Jeremy S. Haley, Sun Young Kim, H. Shanker Rao, Regeneron Genetics Center, David J. Carey, Douglas R. Stewart, Alisa M. Goldstein
Publikováno v:
Cancers; Volume 14; Issue 13; Pages: 3257
Patients with germline pathogenic variants (GPV) in cancer predisposition genes are at increased risk of pancreatic ductal adenocarcinoma (PDAC), the most common type of pancreatic cancer. The genes most frequently found to harbor GPV in unselected P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2bdf1f05237bf8b9bc77957a30a1218
https://pubmed.ncbi.nlm.nih.gov/35805029
https://pubmed.ncbi.nlm.nih.gov/35805029
Autor:
David B. Beck, Dale L. Bodian, Vandan Shah, Uyenlinh L. Mirshahi, Jung Kim, Yi Ding, Samuel J. Magaziner, Natasha T. Strande, Anna Cantor, Jeremy S. Haley, Adam Cook, Wesley Hill, Alan L. Schwartz, Peter C. Grayson, Marcela A. Ferrada, Daniel L. Kastner, David J. Carey, Douglas R. Stewart
Publikováno v:
JAMA. 329:318
ImportanceVEXAS (vacuoles, E1-ubiquitin-activating enzyme, X-linked, autoinflammatory, somatic) syndrome is a disease with rheumatologic and hematologic features caused by somatic variants in UBA1. Pathogenic variants are associated with a broad spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46f16a08d797c482e79246f367253ce8
https://doi.org/10.1001/jama.2022.24836
https://doi.org/10.1001/jama.2022.24836
Autor:
Diane T. Smelser, Jeremy S. Haley, Evan J. Ryer, James R. Elmore, Adam M. Cook, David J. Carey
Publikováno v:
Journal of Vascular Surgery: Venous and Lymphatic Disorders. 10:382-389.e2
The present study sought to determine whether protein-truncating variants (PTVs) in PIEZO1 and CASZ1 genes, previously shown to be associated with varicose veins, were associated with an altered risk of varicose veins.An exome sequence database of 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18f6b1288dfef3ec0a8a8d26db1af2bc
https://doi.org/10.1016/j.jvsv.2021.07.007
https://doi.org/10.1016/j.jvsv.2021.07.007
Publikováno v:
Cancer
BACKGROUND Increased levels of inflammation are associated with many diseases, including cancer. Physical activity can lower breast cancer risk as well as levels of inflammation. The Women In Steady Exercise Research (WISER) Sister trial was a random
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a1b52fd1d22cdcbd9036ac852416749
https://europepmc.org/articles/PMC6952574/
https://europepmc.org/articles/PMC6952574/
Autor:
Kris Ann P. Schultz, Andrew J. Bauer, Jessica N Hatton, Philip S. Rosenberg, David J. Carey, Laura A. Harney, Kandamurugu Manickam, Jeremy S. Haley, Zongming E. Chen, Jung Kim, Amanda Field, Douglas R. Stewart, D. Ashley Hill, Ana F. Best, Alicia Golden, Uyenlinh L. Mirshahi, Ying Hu, Ann G. Carr, Michael F. Murray, Richard Stahl
Publikováno v:
JAMA Network Open
Key Points Question What are the prevalence, risk, and phenotypic spectrum of individuals with a germline putative loss-of-function (pLOF) variant in DICER1 according to a genome-first approach in a population-scale cohort? Findings In this cohort st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c75d5220ab22b4746997ce38dd7f9d59
https://doi.org/10.1001/jamanetworkopen.2021.0112
https://doi.org/10.1001/jamanetworkopen.2021.0112
Autor:
Giampaolo Talamo, Todd D. Schell, Rogerio I. Neves, Jihua Cheng, Joseph J. Drabick, Jeffrey Sivik, Edward J Wyluda, Heath B. Mackley, Jeremy S. Haley, Gavin P. Robertson, Carol Mallon
Publikováno v:
Cancer Biology & Therapy
We report 3 cases of durable complete response (CR) in patients with BRAF-mutated metastatic melanoma who were initially treated unsuccessfully with sequential immunotherapies (high dose interleukin 2 followed by ipilimumab with or without concurrent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b82dc9da2741faac8815d76a809d88f
https://doi.org/10.1080/15384047.2015.1026507
https://doi.org/10.1080/15384047.2015.1026507