Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Jeremy S Duncan"'
Autor:
Yuhki Saito, Soledad Miranda-Rottmann, Matteo Ruggiu, Christopher Y Park, John J Fak, Ru Zhong, Jeremy S Duncan, Brian A Fabella, Harald J Junge, Zhe Chen, Roberto Araya, Bernd Fritzsch, A J Hudspeth, Robert B Darnell
Publikováno v:
eLife, Vol 5 (2016)
The neuron specific RNA-binding proteins NOVA1 and NOVA2 are highly homologous alternative splicing regulators. NOVA proteins regulate at least 700 alternative splicing events in vivo, yet relatively little is known about the biologic consequences of
Externí odkaz:
https://doaj.org/article/53a008d0115a4c659aae01c373fb5e9f
Autor:
Jeremy S Duncan, Bernd Fritzsch
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62046 (2013)
Hair cells of the developing mammalian inner ear are progressively defined through cell fate restriction. This process culminates in the expression of the bHLH transcription factor Atoh1, which is necessary for differentiation of hair cells, but not
Externí odkaz:
https://doaj.org/article/1290b143873a41b19d172a4f0b1bdc29
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30358 (2012)
Atonal homolog1 (Atoh1) is a bHLH transcription factor essential for inner ear hair cell differentiation. Targeted expression of Atoh1 at various stages in development can result in hair cell differentiation in the ear. However, the level and duratio
Externí odkaz:
https://doaj.org/article/07a788d298a44ece8edfbe6361529630
Autor:
Israt Jahan, Ning Pan, Jennifer Kersigo, Lilian E Calisto, Ken A Morris, Benjamin Kopecky, Jeremy S Duncan, Kirk W Beisel, Bernd Fritzsch
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30853 (2012)
In the mammalian inner ear neurosensory cell fate depends on three closely related transcription factors, Atoh1 for hair cells and Neurog1 and Neurod1 for neurons. We have previously shown that neuronal cell fate can be altered towards hair cell fate
Externí odkaz:
https://doaj.org/article/cff64dae99d54709bfb0e9461f700dd9
Autor:
Paige V. Blinkiewicz, Makayla R. Long, Zachary A. Stoner, Elizabeth M. Ketchum, Sydney N. Sheltz-Kempf, Jeremy S. Duncan
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract It has previously been shown that the zinc-finger transcription factor Gata3 has dynamic expression within the inner ear throughout embryonic development and is essential for cochlear neurosensory development. However, the temporal window fo
Externí odkaz:
https://doaj.org/article/c885cfe35fc24172938eaddb81ba6ebf
Publikováno v:
Evolution of Neurosensory Cells and Systems ISBN: 9781003092810
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ffea4052c50a36a632ce3700a2a0d0b
https://doi.org/10.1201/9781003092810-7
https://doi.org/10.1201/9781003092810-7
Publikováno v:
The Senses: A Comprehensive Reference ISBN: 9780128054093
Synopsis This article provides an overview of the molecular development of the vestibular system, beginning at the otic placode stage and ending with the formation of the sensory organs and their components. In addition, a brief overview of the evolu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e27a98da41075fb15412501aa81f855e
https://doi.org/10.1016/b978-0-12-809324-5.23913-8
https://doi.org/10.1016/b978-0-12-809324-5.23913-8
Autor:
Brandon C. Cox, Jeremy S. Duncan
Publikováno v:
The Senses: A Comprehensive Reference
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b470c3033d7a839fb4e264120b379f54
https://doi.org/10.1016/b978-0-12-809324-5.24161-8
https://doi.org/10.1016/b978-0-12-809324-5.24161-8
Autor:
Jeremy S. Duncan, Fadel Tissir, Andrew F. Francl, Michael R. Deans, Danelle Devenport, Michelle L. Stoller
Publikováno v:
Developmental Biology, Vol. 423, p. 126-137 (2017)
Vestibular hair cells of the inner ear are specialized receptors that detect mechanical stimuli from gravity and motion via the deflection of a polarized bundle of stereocilia located on their apical cell surfaces. The orientation of stereociliary bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b760b8696a1b9d83152cb34b97c4f5b
https://doi.org/10.1016/j.ydbio.2017.01.020
https://doi.org/10.1016/j.ydbio.2017.01.020
Autor:
Bernd Fritzsch, Michael R. Deans, Jeremy S. Duncan, Douglas W. Houston, Elizabeth M. Ketchum, Karen L. Elliott, Jennifer Kersigo
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports
Scientific Reports
Inner ear sensory afferent connections establish sensory maps between the inner ear hair cells and the vestibular and auditory nuclei to allow vestibular and sound information processing. While molecular guidance of sensory afferents to the periphery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b44becad0d542640a24c4561a0eef1a8
https://doi.org/10.1038/s41598-019-46553-6
https://doi.org/10.1038/s41598-019-46553-6