Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jeremy Ratiu"'
Autor:
William H. Tomaszewski, Jessica Waibl-Polania, Molly Chakraborty, Jonathan Perera, Jeremy Ratiu, Alexandra Miggelbrink, Donald P. McDonnell, Mustafa Khasraw, David M. Ashley, Peter E. Fecci, Luigi Racioppi, Luis Sanchez-Perez, Michael D. Gunn, John H. Sampson
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Responses to immune checkpoint blockade (ICB) in patients with glioblastoma are limited. Here the authors show that Calmodulin-Dependent Kinase Kinase 2 (CaMKK2) is expressed in tumor associated macrophages and neurons and is associated with resistan
Externí odkaz:
https://doaj.org/article/d2bad1bc29a045f7afdb7b2e7787b8de
Autor:
Paulina M. Wojnarowicz, Marta Garcia Escolano, Yun-Han Huang, Bina Desai, Yvette Chin, Riddhi Shah, Sijia Xu, Saurabh Yadav, Sergey Yaklichkin, Ouathek Ouerfelli, Rajesh Kumar Soni, John Philip, David C. Montrose, John H. Healey, Vinagolu K. Rajasekhar, William A. Garland, Jeremy Ratiu, Yuan Zhuang, Larry Norton, Neal Rosen, Ronald C. Hendrickson, Xi Kathy Zhou, Antonio Iavarone, Joan Massague, Andrew J. Dannenberg, Anna Lasorella, Robert Benezra
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-17 (2021)
Abstract ID proteins are helix-loop-helix (HLH) transcriptional regulators frequently overexpressed in cancer. ID proteins inhibit basic-HLH transcription factors often blocking differentiation and sustaining proliferation. A small-molecule, AGX51, t
Externí odkaz:
https://doaj.org/article/fcc94ce778e043e9991e8da7d30777e4
Autor:
Amaan Bapoo, Jeremy Ratiu
Publikováno v:
Journal of Student Research. 12
Rheumatoid Arthritis (RA) is a chronic, systemic auto-inflammatory disease that targets peripheral joints causing bone erosion, worsened mobility, and lower quality of life. RA is a complex autoimmune disease that develops through the combined action
Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes
Autor:
Matthew C. Funsten, Leonid A. Yurkovetskiy, Andrey Kuznetsov, Derek Reiman, Camilla H.F. Hansen, Katharine I. Senter, Jean Lee, Jeremy Ratiu, Shiva Dahal-Koirala, Dionysios A. Antonopoulos, Gary M. Dunny, Ludvig M. Sollid, David Serreze, Aly A. Khan, Alexander V. Chervonsky
Publikováno v:
Cell Host & Microbe. 31:213-227.e9
Diet and commensals can affect the development of autoimmune diseases like type 1 diabetes (T1D). However, whether dietary interventions are microbe-mediated was unclear. We found that a diet based on hydrolyzed casein (HC) as a protein source protec
Autor:
Jeremy Ratiu, William Barclay, Qun Wang, Sebastian Wellford, Naren Mehta, Melissa Harnois, Devon DiPalma, Sumedha Roy, Alejandra Contreras, Mari Shinohara, David Wiest, Yuan Zhuang
Production of a diverse peripheral T cell compartment requires massive expansion of the bone marrow progenitors that seed the thymus. There are two main phases of expansion during T cell development, following T lineage commitment at the DN2 stage an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ea44ecc5dea50b3c93e348368944c3b
https://doi.org/10.21203/rs.3.rs-1226201/v1
https://doi.org/10.21203/rs.3.rs-1226201/v1
Autor:
Caroline McPhee Leeth, Muneer Hasham, Jeremy Ratiu, Jing Zhu, Harry Chapman, Jane Branca, Kevin Mills, David Serreze
Publikováno v:
The Journal of Immunology. 196:47.6-47.6
While CD4+ and CD8+ T lymphocytes are ultimately responsible for the destruction of insulin-producing beta cells resulting in clinical type 1 diabetes (T1D), B lymphocytes are also critical pathogenic players in T1D development in NOD mice and likely